Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Rural communities face higher rates of heart disease and risk factors

A research team funded by the National Institutes of Health (NIH) uncovered higher rates of heart disease and worse heart health affecting adults living in rural communities compared to urban areas and the factors that likely drive these differences.

1 Apr 2025

Study links low LDL-C levels to reduced risk of dementia

People with low levels of low-density lipoprotein cholesterol (LDL-C) in their blood have a lower risk of dementia, including lower risk of Alzheimer's disease related dementia, shows a study published online today in the Journal of Neurology Neurosurgery & Psychiatry.

1 Apr 2025

What blueberries do and don’t do for your microbiome and heart

Regular blueberry consumption for 12 weeks enriched Coriobacteriales incertae sedis in the gut microbiota of older overweight adults. However, this microbial shift was not linked to significant improvements in cardiometabolic biomarkers.

31 Mar 2025

Five lifestyle changes by 50 can add a decade to your life, global study finds

Study estimates the global lifetime risk and benefits of modifying cardiovascular risk factors like hypertension, smoking, and obesity by age 50, showing significant improvements in both life expectancy and quality of life. It highlights the importance of early intervention and midlife changes in preventing cardiovascular disease and mortality.

31 Mar 2025

AI-based imaging performs equally well as ultrasound in guiding heart procedures

Patients with narrowing of at least 50% in three major coronary arteries did equally well when treated with a minimally invasive stent placement guided either by ultrasound-based imaging or by a novel, artificial-intelligence-powered (AI), non-invasive imaging technique derived from angiography, researchers reported at the American College of Cardiology's Annual Scientific Session (ACC.25).

31 Mar 2025

Traditional Chinese medicine targets cholesterol metabolism for cancer treatment

Researchers explore how natural compounds in traditional Chinese medicine can modulate cholesterol metabolism to combat cancer.

31 Mar 2025

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

In sharp contrast to earlier studies, patients with severe triple-vessel heart disease fared equally well whether they underwent open-heart bypass surgery (CABG) or a less invasive procedure called PCI (percutaneous coronary intervention) at five years of follow-up, according to research presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

New trial shows oral semaglutide reduces cardiovascular events in diabetes patients

Both the injectable and oral forms of semaglutide, a glucagon-like peptide-1 receptor agonist, have gained recent attention for their effectiveness against weight gain, high blood sugar, and even alcohol cravings.

31 Mar 2025

Not all Chinese food is equal: study ranks cuisines by inflammatory potential

Researchers analyzed 980 dishes from eight major Chinese cuisines to evaluate their nutritional profiles and inflammatory potential using the Dietary Inflammatory Index (DII).

31 Mar 2025

WARRIOR trial finds no impact of intensive therapy on heart events in women

An intensive three-drug regimen of heart medications did not significantly impact the rate of serious cardiovascular events at five years in women who experienced signs and symptoms of ischemia, or insufficient blood flow to the heart muscle, but had no blockages in their heart's arteries, according to research presented at the American College of Cardiology's Annual Scientific Session.

29 Mar 2025

Semaglutide improves maximal walking distance in people with symptomatic PAD and Type 2 diabetes

Semaglutide, a glucagon-like peptide 1 (GLP-1) agonist, significantly improved maximal walking distance in people with symptomatic peripheral artery disease (PAD) and Type 2 diabetes in the first-of-its kind trial to evaluate the use of a GLP-1 agonist to manage PAD.

29 Mar 2025

Study aims to determine best method for statin prescription in coronary heart disease

A new study by researchers at Intermountain Health in Salt Lake City aims to determine the best method to screen and evaluate patients who are at risk of developing coronary heart disease and which patients would benefit from taking a statin medication to lower cholesterol.

29 Mar 2025

Zero coronary artery calcium score predicts low heart risk at any age

Having a coronary artery calcium (CAC) score of zero has generally been accepted as a marker of a very low risk of having a cardiac event within the next five years. However, age is a strong contributor to coronary risk, with risk increasing markedly as people age.

29 Mar 2025

Older Americans support insurance coverage for obesity medications

A large majority of older Americans feel that health insurance – including Medicare – should cover anti-obesity medications, according to a new University of Michigan study.

27 Mar 2025

Wearable technologies may improve exercise adherence in people with Type 2 Diabetes

Wearable mobile health technology could help people with Type 2 Diabetes (T2D) to stick to exercise regimes that help them to keep the condition under control, a new study reveals.

26 Mar 2025

Pass the (iodized) salt: Iodine deficiency drives frailty risk in people with diabetes

Lower iodine levels and use of non-iodized salt are linked to a higher risk of frailty in people with type 2 diabetes. This association is strongest in those with thyroid dysfunction, underscoring the importance of adequate iodine intake.

26 Mar 2025

This molecule links your diet to stroke and Alzheimer’s—here’s how to stop it

A new review explores how TMAO, a gut-derived metabolite from red meat and other foods, contributes to heart and brain diseases. It also highlights promising interventions—like plant-based diets, probiotics, and nutraceuticals—to lower TMAO levels and reduce health risks.

26 Mar 2025

Addressing cardiovascular risk factors in emerging adulthood

Many teenagers enter adulthood with significant risk factors for cardiovascular disease, and the transition from adolescence to adulthood is a key time to address these risk factors and reduce the risk of developing future cardiovascular disease, according to a new American Heart Association scientific statement published today in the Journal of the American Heart Association.

26 Mar 2025

New guidelines recommend 2 hours of weekly exercise for postpartum women

New mums should be strongly encouraged to begin clocking up at least two hours of moderate to vigorous intensity physical activity such as brisk walking and muscle strengthening exercises each week in the first three months after birth, when physically able, to improve health and well-being, say experts in a new guideline published by the British Journal of Sports Medicine.

26 Mar 2025

Epigenetic scores offer new insights into cardiometabolic disease prevention

A new study explores how epigenetic markers-chemical modifications that influence gene activity-can help predict the risk of developing cardiometabolic diseases and guide personalized prevention strategies.

25 Mar 2025

Cholesterol News and Research

Further Reading

Rural communities face higher rates of heart disease and risk factors

Study links low LDL-C levels to reduced risk of dementia

What blueberries do and don’t do for your microbiome and heart

Five lifestyle changes by 50 can add a decade to your life, global study finds

AI-based imaging performs equally well as ultrasound in guiding heart procedures

Traditional Chinese medicine targets cholesterol metabolism for cancer treatment

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

New trial shows oral semaglutide reduces cardiovascular events in diabetes patients

Not all Chinese food is equal: study ranks cuisines by inflammatory potential

WARRIOR trial finds no impact of intensive therapy on heart events in women

Semaglutide improves maximal walking distance in people with symptomatic PAD and Type 2 diabetes

Study aims to determine best method for statin prescription in coronary heart disease

Zero coronary artery calcium score predicts low heart risk at any age

Older Americans support insurance coverage for obesity medications

Wearable technologies may improve exercise adherence in people with Type 2 Diabetes

Pass the (iodized) salt: Iodine deficiency drives frailty risk in people with diabetes

This molecule links your diet to stroke and Alzheimer’s—here’s how to stop it

Addressing cardiovascular risk factors in emerging adulthood

New guidelines recommend 2 hours of weekly exercise for postpartum women

Epigenetic scores offer new insights into cardiometabolic disease prevention

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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