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Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

A recent viewpoint illustrated that evaluating T cell responses to COVID-19 is essential to inform public health initiatives.

29 Mar 2022

Results of Phase 3 Nanocovax SARS-CoV-2 vaccine trial suggest robust effectiveness

A new study presented the findings of the Phase 3 trial of the Nanocovax coronavirus disease 2019 (COVID-19) vaccine.

29 Mar 2022

Chaperone-mediated autophagy needed to protect against atherosclerosis

Revving up a process that slows down as we age may protect against atherosclerosis, a major cause of heart attacks and strokes.

28 Mar 2022

Durability and functionality of the humoral and T-cell response to SARS-CoV-2 and its variants in recovered patients

A recent study investigated the potency and functionality of T-cell and humoral responses against the SARS-CoV-2 wild-type strain and its variants.

28 Mar 2022

Study finds that Omicron variant preferentially uses the endosome pathway through mutation in the spike protein

A recent study assessed the role of the SARS-CoV-2 Omicron spike H655Y mutation on viral entry pathways.

24 Mar 2022

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

A recent study demonstrated that RNA interference could prophylactically protect against SARS-CoV-2.

24 Mar 2022

Importance of Numb-associated kinases in SARS-CoV-2 infection

A new study posted to the bioRxiv* preprint server has focussed on assessing four members of the NAK family that are associated with SARS-CoV-2 infection. These kininases could act as a target for the development of effective COVID-19 therapeutics.

23 Mar 2022

Scientists identify a promising strategy for stopping Ebola virus polymerase

To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase.

23 Mar 2022

Novel nanoparticle-based COVID vaccines induce long-term neutralizing antibody response

Researchers report the results for a new SARS-CoV-2 vaccine currently in Phase III clinical trial known as I53-50.

22 Mar 2022

Predatory bacterium can sculpt its own shape to fit inside the prey

Scientists have found that a predatory bacterium, capable of invading and consuming harmful bugs such as E.coli and Salmonella, can sculpt its own shape to fit inside its prey.

22 Mar 2022

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Researchers reported a hybrid approach comprising computational models and high throughput screening to discover allosteric ACE2 binders inhibiting viral replication without interrupting ACE2 renal, pulmonary, immune, and cardiovascular functions.

22 Mar 2022

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

In a new study, researchers aimed to determine if peptidyl-arginine deiminases inhibitors may be used as a novel class of host-targeting antivirals against human coronaviruses.

21 Mar 2022

Glycogen synthase kinase-3 inhibitors found to attenuate COVID-19-associated cytokine storm

In a new study, researchers investigated whether the SARS-CoV-2 spike protein and its S2 subunit induced the expression of C–X–C motif chemokine 10, a subset of cytokine.

21 Mar 2022

Study aimed to identify the direct pathway that associates integrins with vascular dysregulation during SARS-CoV-2 infection

Researchers demonstrated the role of integrin signaling in vascular dysfunction associated with SARS-CoV-2 infection.

21 Mar 2022

Study evaluates COVID-19 vaccination with recombinant accessory protein-deficient SARS-CoV-2

Researchers assessed the impact of recombinant accessory protein-deficient severe acute respiratory syndrome coronavirus 2 immunization against SARS-CoV-2 transmission and disease severity.

18 Mar 2022

Researchers find turbocharger for memory in the brain cells of mice

Scientists have long known that learning requires the flow of calcium into and out of brain cells. But researchers at Columbia's Zuckerman Institute have now discovered that floods of calcium originating from within neurons can also boost learning.

17 Mar 2022

Scientists discover mechanism that enables Listeria-infected cells to escape immune responses

Some "hypervirulent" strains of Listeria monocytogenes have a greater capacity to infect the central nervous system.

16 Mar 2022

Imaging reveals molecular process used by corals to control algal symbionts' subcellular environment

Researchers at UC San Diego's Scripps Institution of Oceanography have discovered a novel molecular process that corals use to control the subcellular environment of the algae that live inside them.

11 Mar 2022

Novel genetic relationships with severe SARS-CoV-2

Researchers discovered multiple novel genetic processes underpinning severe COVID-19 using genome-wide association studies and meta-analyses.

11 Mar 2022

Targeting regulation of subcellular architecture may hold opportunities to treat metabolic diseases

Cells use their molecular architecture to regulate their metabolic functions, and repairing diseased cells' architecture to a healthier state can also repair metabolism, according to a study led by Harvard T.H. Chan School of Public Health researchers.

10 Mar 2022

Intracellular News and Research

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

Results of Phase 3 Nanocovax SARS-CoV-2 vaccine trial suggest robust effectiveness

Chaperone-mediated autophagy needed to protect against atherosclerosis

Durability and functionality of the humoral and T-cell response to SARS-CoV-2 and its variants in recovered patients

Study finds that Omicron variant preferentially uses the endosome pathway through mutation in the spike protein

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

Importance of Numb-associated kinases in SARS-CoV-2 infection

Scientists identify a promising strategy for stopping Ebola virus polymerase

Novel nanoparticle-based COVID vaccines induce long-term neutralizing antibody response

Predatory bacterium can sculpt its own shape to fit inside the prey

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

Glycogen synthase kinase-3 inhibitors found to attenuate COVID-19-associated cytokine storm

Study aimed to identify the direct pathway that associates integrins with vascular dysregulation during SARS-CoV-2 infection

Study evaluates COVID-19 vaccination with recombinant accessory protein-deficient SARS-CoV-2

Researchers find turbocharger for memory in the brain cells of mice

Scientists discover mechanism that enables Listeria-infected cells to escape immune responses

Imaging reveals molecular process used by corals to control algal symbionts' subcellular environment

Novel genetic relationships with severe SARS-CoV-2

Targeting regulation of subcellular architecture may hold opportunities to treat metabolic diseases

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