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New evidence shows blood-brain barrier remains intact in Alzheimer's mouse model

A team of scientists at Texas Tech University Health Sciences Center (TTUHSC) has published new evidence suggesting that the brain's protective shield - known as the blood-brain barrier (BBB) - remains largely intact in a commonly used mouse model of Alzheimer's disease.

29 Sep 2025

Combining radiopharmaceuticals with targeted radiation improves progression-free survival in prostate cancer patients

A new clinical trial finds that people with a limited number of metastases from recurrent prostate cancer lived significantly longer without disease progression when they received a radiopharmaceutical drug before targeted radiation, compared with radiation alone.

29 Sep 2025

Novel biosensing platform provides quantitative graded evaluation of mild to severe liver injury

Real-time monitoring of key biomarkers is a critical prerequisite for early disease diagnosis and personalized therapy. Early detection of liver function impairment particularly relies on the measurement of serum alanine aminotransferase (ALT).

29 Sep 2025

Super-resolution imaging unlocks the role of transporter nanoclusters in tumor metabolism

Serine serves as a metabolic nexus in tumors, coordinating one-carbon metabolism, nucleotide synthesis, and redox regulation. In recent years, targeting the serine metabolic pathway, particularly the rate-limiting enzyme PHGDH, has attracted considerable attention as a promising anticancer strategy.

29 Sep 2025

IGF2BP3 protein drives leukemia growth by linking metabolism and RNA control

Cancer cells are relentless in their quest to grow and divide, often rewiring their metabolism and modifying RNA to stay one step ahead.

26 Sep 2025

Cumulative social advantage linked to slower biological aging and lower inflammation

The cumulative effect of social advantages across a lifetime – from parental warmth in childhood to friendship, community engagement and religious support in adulthood – may slow the biological processes of aging.

26 Sep 2025

Natural psychoactive molecule DMT reduces harmful effects of stroke in animal models

DMT, or dimethyltryptamine is a natural psychoactive molecule found in many plants and mammals. According to an article published in Science Advances, researchers from the HUN-REN BRC Institute of Biophysics and Semmelweis University Heart and Vascular Centre found that DMT reduces the harmful effects of stroke in animal models and cell culture experiments.

26 Sep 2025

Researchers develop tool to predict how patients will respond to common multiple sclerosis drug

Brazilian researchers, in partnership with French institutions, have developed a tool that can predict how patients will respond to natalizumab, one of the most commonly used drugs for treating multiple sclerosis.

25 Sep 2025

Analysis shows potential impact of deep NIH budget cuts on future drug development

Gleevec, a cancer drug first approved for sale in 2001, has dramatically changed the lives of people with chronic myeloid leukemia.

25 Sep 2025

Gladstone researchers expand mission to tackle emerging infectious threats

From influenza and COVID-19 to HIV, viruses continue to pose a serious danger to global health.

25 Sep 2025

Babies living with dogs show better lung function and reduced asthma rates

Babies exposed to dog allergens in the home have a lower risk of developing asthma by the age of five years, according to research that will be presented at the European Respiratory Society (ERS) Congress in Amsterdam, the Netherlands.

25 Sep 2025

Mount Sinai study maps protein networks driving Alzheimer’s disease pathogenesis

A new study led by the Icahn School of Medicine at Mount Sinai offers one of the most comprehensive views yet of how brain cells interact in Alzheimer's disease, mapping protein networks that reveal communication failures and point to new therapeutic opportunities.

25 Sep 2025

Targeting TGF-β signaling as a strategy to treat liver fibrosis

Liver fibrosis, a pathological scarring process resulting from chronic liver injury, represents a significant global health burden due to its potential progression to cirrhosis and hepatocellular carcinoma.

25 Sep 2025

Picoquant invests in Fluobrick Solutions to simplify access to single molecule research

PicoQuant GmbH announces its investment in FluoBrick Solutions GmbH, a newly founded Berlin-based start-up focused on giving life science researchers in academia and pharma diagnostics access to the power of single molecule techniques.

25 Sep 2025

Scientists map step-by-step activation of brain receptors

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, know that even slight changes in their activity level can mean the difference between normal function and serious neurological disorders.

24 Sep 2025

Influenza infection in pregnant mice linked to fetal brain exposure

A new study from the University of Illinois Urbana-Champaign shows, for the first time, that severe flu infection in pregnant mice leads to a breakdown in placental and brain barriers, leading to the accumulation of potentially harmful molecules in the fetal brain.

24 Sep 2025

Molecule News and Research

New evidence shows blood-brain barrier remains intact in Alzheimer's mouse model

Combining radiopharmaceuticals with targeted radiation improves progression-free survival in prostate cancer patients

Novel biosensing platform provides quantitative graded evaluation of mild to severe liver injury

Super-resolution imaging unlocks the role of transporter nanoclusters in tumor metabolism

IGF2BP3 protein drives leukemia growth by linking metabolism and RNA control

Cumulative social advantage linked to slower biological aging and lower inflammation

Natural psychoactive molecule DMT reduces harmful effects of stroke in animal models

Researchers develop tool to predict how patients will respond to common multiple sclerosis drug

Analysis shows potential impact of deep NIH budget cuts on future drug development

Gladstone researchers expand mission to tackle emerging infectious threats

Babies living with dogs show better lung function and reduced asthma rates

Mount Sinai study maps protein networks driving Alzheimer’s disease pathogenesis

Targeting TGF-β signaling as a strategy to treat liver fibrosis

Picoquant invests in Fluobrick Solutions to simplify access to single molecule research

Scientists map step-by-step activation of brain receptors

Influenza infection in pregnant mice linked to fetal brain exposure

AI-guided platform improves design and efficiency of therapeutic nanoparticles

NIH funds USC team to develop a selective Alzheimer’s drug for APOE4 carriers

GPR120 plays a key role in mediating the effects of n-3 fatty acids on mammary function

Study reveals how a key spinal circuit shapes the choreography of sex

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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