Pancreatic Cancer News and Research

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Pancreatic cancer is the fourth leading cause of all cancer deaths in the United States and the third leading cause of cancer deaths in individuals ages 40 to 60. Approximately 37,000 Americans are diagnosed with pancreatic cancer each year, and, each year, approximately the same number die from it. Often, pancreatic cancer is found too late for surgical intervention, and chemotherapy and radiation treatments have little effect.

Researchers identify protein that may represent a safer treatment target for pancreatic cancer

Researchers from Queen Mary University of London, have identified a protein that may represent a novel therapeutic target for the treatment of pancreatic cancer.

22 Jan 2021

Researchers develop ultra-small nanomedicines to target intractable cancers

Ultra-small nanomedicines of approximately 18 nm were fabricated by dynamic ion-pairing between Y-shaped block copolymers and nucleic acid drugs, such as siRNA and antisense drugs.

19 Jan 2021

New computational technique accurately differentiates between data from tumor cells and normal cells

In an effort to address a major challenge when analyzing large single-cell RNA-sequencing datasets, researchers from The University of Texas MD Anderson Cancer Center have developed a new computational technique to accurately differentiate between data from cancer cells and the variety of normal cells found within tumor samples.

18 Jan 2021

Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Reprogramming the rich connective tissue microenvironment of a liver cancer known as intrahepatic cholangiocarcinoma (ICC) inhibits its progression and resistance to standard chemotherapy in animal models, researchers from Massachusetts General Hospital have found.

12 Jan 2021

Master Regulator proteins control cancer transcriptional identity

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the Master Regulator proteins that control the cancer's transcriptional state were virtually identical, independent of the specific genetic mutations of each patient.

11 Jan 2021

Opioid use may increase the risk of pancreatic cancer

Researchers at Rush University Medical Center have found that opioid use might increase a person's risk of developing pancreatic cancer.

6 Jan 2021

Researchers develop α-emitting cancer therapy using a novel drug targeting LAT1

A cancer-specific L-type amino acid transporter 1 (LAT1) is highly expressed in cancer tissues.

4 Jan 2021

FDA authorizes first device to treat patients with walled-off pancreatic necrosis

Today, the U.S. Food and Drug Administration authorized marketing of the EndoRotor System to resect (cut out) and remove necrotic (dead) tissue for patients with walled-off pancreatic necrosis (WOPN), a potentially deadly condition which can occur several weeks after an episode of severe acute pancreatitis, often requiring tissue removal.

23 Dec 2020

Research could lead to potential new treatments for mutant RAS-driven cancers

Scientists have dedicated huge amounts of time and resources to better understanding the causes and mechanisms of cancer growth.

15 Dec 2020

Compound derived from thunder god vine could improve outcomes for pancreatic cancer patients

The results of a pre-clinical study led by researchers at the Translational Genomics Research Institute, an affiliate of City of Hope, suggest how a compound derived from the thunder god vine -- an herb used in China for centuries to treat joint pain, swelling and fever -- is able to kill cancer cells and potentially improve clinical outcomes for patients with pancreatic cancer.

14 Dec 2020

New combination therapy has potential to treat aggressive cancers with common mutations

Scientists have long known that therapies that target the cancer-driving MAPK pathway are only effective in a handful of cancers with specific mutations in a cancer gene called BRAF, and these cancers that initially respond to the therapy often end up developing resistance to the treatment, resulting in relapse for many patients.

14 Dec 2020

Imaging, morphologic metrics associated with pathologic response in pancreatic cancer patients

According to an open-access Editor's Choice article in ARRS' American Journal of Roentgenology (AJR), post-neoadjuvant therapy (NAT) changes in metabolic metrics from PET/MRI and morphologic metrics from CT were associated with pathologic response and overall survival in patients with pancreatic ductal adenocarcinoma (PDA).

9 Dec 2020

Pancreatic Cancer News and Research

Further Reading

Researchers identify protein that may represent a safer treatment target for pancreatic cancer

Researchers develop ultra-small nanomedicines to target intractable cancers

New computational technique accurately differentiates between data from tumor cells and normal cells

Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Master Regulator proteins control cancer transcriptional identity

Opioid use may increase the risk of pancreatic cancer

Researchers develop α-emitting cancer therapy using a novel drug targeting LAT1

FDA authorizes first device to treat patients with walled-off pancreatic necrosis

Research could lead to potential new treatments for mutant RAS-driven cancers

Compound derived from thunder god vine could improve outcomes for pancreatic cancer patients

New combination therapy has potential to treat aggressive cancers with common mutations

Imaging, morphologic metrics associated with pathologic response in pancreatic cancer patients

Researchers identify new way to disrupt process that promotes the growth of pancreatic cancers

Henry Ford Health System announces receipt of $16 million gift to Henry Ford Pancreatic Cancer Center

Researchers discover new functions of key cellular machine in cancer

Brain protein plays a major role in the development and growth of pancreatic cancer

JNCCN: Cost-effectiveness of olaparib for metastatic pancreatic cancer

Researchers develop novel chemo-immunotherapy agent to treat pancreatic tumors

Novel insights on a common protein could have broad biomedical applications

How COVID death counts become the stuff of conspiracy theories

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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