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Researchers identify potential drug target that may improve cognition in people with mental illnesses

More than a dozen drugs are known to treat symptoms such as hallucinations, erratic behaviors, disordered thinking and emotional extremes associated with schizophrenia, bipolar disorder and other severe mental illnesses.

3 Dec 2020

Designed proteins assemble antibodies into modular nanocages

With cues from nature, designing functional molecules enables scientists to nanoengineer and customize for specific uses.

3 Dec 2020

Long-range allosteric influences on SARS-COV-2-ACE2 stability and detachment

The COVID-19 pandemic is caused by SARS-CoV-2, a novel beta-coronavirus which has numerous spike proteins on its membrane.

3 Dec 2020

N-Glycosylation sites may contribute to spike-mediated invasion by SARS-CoV-2

The sugar residues decorating the spike (S) protein of SARS-CoV-2 are essential to the viral-receptor binding.

3 Dec 2020

COVID-19 mutation mapping identifies escape mutations against therapeutic antibodies

A new study maps all known mutations in the SARS-CoV-2 virus, showing how each contributes to escape from individual antibodies.

3 Dec 2020

Pomegranate extract could inhibit the virus that causes COVID-19

Researchers have conducted a study demonstrating the potential antiviral effects of pomegranate extract against SAR-CoV-2.

3 Dec 2020

Novel “multitope” vaccine shows promise in the fight against COVID-19

Researchers have demonstrated the potential of a protein-peptide vaccine to protect against infection with SARS-CoV-2, the agent that causes COVID-19.

3 Dec 2020

Chronic kidney disease strongly associated with COVID-related hospitalization

An analysis of Geisinger's electronic health records has revealed chronic kidney disease to be the leading risk factor for hospitalization from COVID-19.

2 Dec 2020

Study finds potential target for the treatment of anxiety and obsessive-compulsive disorder

Anxiety disorders and obsessive-compulsive disorder (OCD) are disabling psychiatric conditions and the major contributors to global burden of nonfatal illness.

2 Dec 2020

Carrot-based Japanese herbal medicine may improve muscle complications associated with COPD

Chronic obstructive pulmonary disease (COPD) is a lung disease caused by long-term inhalation of harmful gases such as cigarette smoke.

2 Dec 2020

Spanish-originated SARS-CoV-2 variant A222V shows rapid spread in Lazio, Italy

A startling new study reports the rapid rise to dominance of a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain in Italy. This strain, termed the GV clade, is characterized by a single point mutation.

2 Dec 2020

Scientists detect a sarbecovirus phylogenetically related to SARS-CoV-2 from bats in Japan

A team of researchers at the University of Tokyo in Japan have detected a sarbecovirus, called Rc-o319, which is phylogenetically positioned in the same clade as SARS-CoV-2 in Rhinolophus cornutus bats in Japan.

2 Dec 2020

SARS-CoV-2 deletion mutations may have attenuated infectivity in some strains

A team of researchers at the University of Hong Kong has identified a panel of SARS-CoV-2 variants, called Del-mut, which contains a deletion in the S1/S2 junction. Upon investigating one of the deleted variants in animal models, they found that Del-mut-1 is attenuated in its ability to cause disease or pathological changes.

2 Dec 2020

Autoantigen may help prevent and treat cardiovascular disease

Mitochondrial protein ALDH4A1 has been identified as an autoantigen implicated in atherosclerosis.

2 Dec 2020

Improved understanding of exposome-drug interactions could help prescribe effective drug doses

According to scientific estimations, humans are exposed to at least 10,000 to 100,000 environmental and exogenous compounds in an individual lifetime, which are mainly absorbed through our dietary.

2 Dec 2020

POSTECH researchers solve the enigma to treating neurological diseases

Neurological diseases of the brain such as dementia, autism and schizophrenia are now a growing social problem. Nevertheless, studies on their definitive cause are still insufficient.

2 Dec 2020

Researchers describe cellular mediator that makes muscle adaptation to exercise possible

The onset of any physical exercise program causes muscle pain that can hinder movements as simple as getting up from a sofa. With time and a little persistence, the muscles become accustomed to the effort, developing more strength and endurance.

1 Dec 2020

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Dana-Farber Cancer Institute researchers will present more than 40 research studies at the virtual 62nd American Society of Hematology Annual Meeting on December 5-8, including two studies that were selected for inclusion in the official press program.

1 Dec 2020

Research suggests plant flavonols could serve as effective antivirals for SARS-CoV-2

Researchers in Algeria have reviewed some of the evidence suggesting that flavonols commonly found in many plants and vegetables could be used as a therapeutic approach to coronavirus disease 2019 (COVID-19).

1 Dec 2020

Does smoking increase risk of COVID-19 hospitalization?

A study conducted by UK researchers has found that patients hospitalized with coronavirus disease 2019 (COVID-19) were less likely to be current smokers than patients who had been admitted with other types of respiratory viral infections last year (2019).

1 Dec 2020

Receptor News and Research

Researchers identify potential drug target that may improve cognition in people with mental illnesses

Designed proteins assemble antibodies into modular nanocages

Long-range allosteric influences on SARS-COV-2-ACE2 stability and detachment

N-Glycosylation sites may contribute to spike-mediated invasion by SARS-CoV-2

COVID-19 mutation mapping identifies escape mutations against therapeutic antibodies

Pomegranate extract could inhibit the virus that causes COVID-19

Novel “multitope” vaccine shows promise in the fight against COVID-19

Chronic kidney disease strongly associated with COVID-related hospitalization

Study finds potential target for the treatment of anxiety and obsessive-compulsive disorder

Carrot-based Japanese herbal medicine may improve muscle complications associated with COPD

Spanish-originated SARS-CoV-2 variant A222V shows rapid spread in Lazio, Italy

Scientists detect a sarbecovirus phylogenetically related to SARS-CoV-2 from bats in Japan

SARS-CoV-2 deletion mutations may have attenuated infectivity in some strains

Autoantigen may help prevent and treat cardiovascular disease

Improved understanding of exposome-drug interactions could help prescribe effective drug doses

POSTECH researchers solve the enigma to treating neurological diseases

Researchers describe cellular mediator that makes muscle adaptation to exercise possible

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Research suggests plant flavonols could serve as effective antivirals for SARS-CoV-2

Does smoking increase risk of COVID-19 hospitalization?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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