Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Ceregene announces new data from CERE-120 clinical trial on Parkinson's

Ceregene Inc., a biotechnology company developing treatments for neurodegenerative diseases such as Parkinson's disease, will present new data demonstrating long-term, biologically-active expression of neurturin, a nervous system growth factor delivered to the degenerating dopamine nerves in patients with Parkinson's disease following treatment with CERE-120.

19 May 2012

Certain types of fat associated with worse memory and overall cognitive function

It has been known for years that eating too many foods containing "bad" fats, such as saturated fats or trans fats, isn't healthy for your heart. However, according to new research from Brigham and Women's Hospital (BWH), one "bad" fat-saturated fat-was found to be associated with worse overall cognitive function and memory in women over time. By contrast, a "good" fat-mono-unsaturated fat was associated with better overall cognitive function and memory.

19 May 2012

ACE Foundation, CRG partner to research into neurodegenerative diseases

The Centre for Genomic Regulation (CRG) and the ACE Foundation - Barcelona Alzheimer Treatment & Research Centre, have signed a collaboration agreement to carry out scientific projects related to neurodegenerative diseases.

19 May 2012

Large survey of genetic variation offers insights into human diseases

A large survey of human genetic variation, published today in the online version of the journal Science, shows that rare genetic variants are not so rare after all and offers insights into human diseases.

19 May 2012

Regular eating times, extended daily fasting may prevent diabetes, obesity

It turns out that when we eat may be as important as what we eat. Scientists at the Salk Institute for Biological Studies have found that regular eating times and extending the daily fasting period may override the adverse health effects of a high-fat diet and prevent obesity, diabetes and liver disease in mice.

18 May 2012

Avraham initiates ladostigil Phase 2 trial in MCI

Avraham Pharmaceuticals Ltd. announced today the commencement of a Phase 2 clinical trial to evaluate the safety and efficacy of ladostigil in patients diagnosed with mild cognitive impairment.

18 May 2012

Researchers identify novel base modification in RNA

Over the past decade, research in the field of epigenetics has revealed that chemically modified bases are abundant components of the human genome and has forced us to abandon the notion we've had since high school genetics that DNA consists of only four bases.

18 May 2012

Scientists investigate how ApoE4 gene contributes to Alzheimer's disease

A well-known genetic risk factor for Alzheimer's disease triggers a cascade of signaling that ultimately results in leaky blood vessels in the brain, allowing toxic substances to pour into brain tissue in large amounts, scientists report May 16 in the journal Nature.

17 May 2012

Damage to brain white matter connections may be the cause of Phineas Gage's behavioral changes

Poor Phineas Gage. In 1848, the supervisor for the Rutland and Burlington Railroad in Vermont was using a 13-pound, 3-foot-7-inch rod to pack blasting powder into a rock when he triggered an explosion that drove the rod through his left cheek and out of the top of his head. As reported at the time, the rod was later found, "smeared with blood and brains."

17 May 2012

Study reveals pathway that may help slow development of multiple myeloma

Researchers at NYU School of Medicine have identified a target for slowing the progression of multiple myeloma by using currently available drugs.

17 May 2012

Head impacts may worsen contact sport athletes’ ability to acquire new information

A new study suggests that head impacts experienced during contact sports such as football and hockey may worsen some college athletes' ability to acquire new information. The research is published in the May 16, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

17 May 2012

First Edition: May 16, 2012

Today's headlines highlight the growing partisan faultlines regarding budget issues, including spending cuts and entitlement reforms.

16 May 2012

HHS announcing finalized Alzheimer's plan

The plan, which includes an emphasis on research, sets 2025 as the target date for finding effective treatments for this disease.

16 May 2012

Ono, Scil Proteins partner to discover and develop new Affilin therapeutics

Scil Proteins GmbH, a private biotech company specializing in the research, development and production of recombinant proteins, today announced that it has signed a collaboration agreement with Ono Pharmaceutical Co., Ltd., for the joint discovery and development of new Affilin therapeutics to treat various diseases.

15 May 2012

Using storytelling to combat Alzheimer's; Health coverage changes prompt aging, disabled care concerns

NPR examines a new way to combat Alzheimer's -- with storytelling. In the meantime, health care changes to programs and budgets have some worried about how they will affect the aging and those with disabilities.

15 May 2012

First Edition: May 14, 2012

In today's headlines, a report about how the Ryan budget plan -- specifically, its Medicare changes -- is playing in congressional races.

14 May 2012

Phase II trial to examine effects of resveratrol on individuals with mild to moderate dementia

A national, phase II clinical trial examining the effects of resveratrol on individuals with mild to moderate dementia due to Alzheimer's disease has begun as more than two dozen academic institutions recruit volunteers in the coming months. R. Scott Turner, M.D., Ph.D., director of Georgetown University Medical Center's Memory Disorders Program, is the lead investigator for the national study.

14 May 2012

Excess brain activity contributes to amnestic mild cognitive impairment

A study led by a Johns Hopkins neuroscientist and published in the May 10 issue of the journal Neuron suggests a potential new therapeutic approach for improving memory and interrupting disease progression in patients with a form of cognitive impairment that often leads to full-blown Alzheimer's disease.

11 May 2012

Longer looks: More 20-30 somethings are taking care of elderly, dissecting solutions to obesity problem

At 30, Suzette Armijo cares for her widowed 86-year-old grandmother, a retired National Park Service ranger in the final stages of Alzheimer's disease, while holding down a fulltime job, a part-time job and raising a 4-year-old son. "This was nothing that I had planned for," says Armijo, who moved her grandmother Elizabeth Armijo into a nearby six-bed assisted living home because veterans' benefits "wouldn't pay for her to live with me."

11 May 2012

Resverlogix completes RVX-208 Phase 2b trial on CVD

Resverlogix Corp. is pleased to announce that dosing in SUSTAIN, a Phase 2b clinical trial to assess lipid trends and safety of RVX-208, has been completed on schedule.

10 May 2012

Alzheimer's Disease News and Research

Further Reading

Ceregene announces new data from CERE-120 clinical trial on Parkinson's

Certain types of fat associated with worse memory and overall cognitive function

ACE Foundation, CRG partner to research into neurodegenerative diseases

Large survey of genetic variation offers insights into human diseases

Regular eating times, extended daily fasting may prevent diabetes, obesity

Avraham initiates ladostigil Phase 2 trial in MCI

Researchers identify novel base modification in RNA

Scientists investigate how ApoE4 gene contributes to Alzheimer's disease

Damage to brain white matter connections may be the cause of Phineas Gage's behavioral changes

Study reveals pathway that may help slow development of multiple myeloma

Head impacts may worsen contact sport athletes’ ability to acquire new information

First Edition: May 16, 2012

HHS announcing finalized Alzheimer's plan

Ono, Scil Proteins partner to discover and develop new Affilin therapeutics

Using storytelling to combat Alzheimer's; Health coverage changes prompt aging, disabled care concerns

First Edition: May 14, 2012

Phase II trial to examine effects of resveratrol on individuals with mild to moderate dementia

Excess brain activity contributes to amnestic mild cognitive impairment

Longer looks: More 20-30 somethings are taking care of elderly, dissecting solutions to obesity problem

Resverlogix completes RVX-208 Phase 2b trial on CVD

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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