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New insights reveal how Candida albicans settle and persist in the gut

About 80% of people have the fungus Candida albicans in their gut. Although most of the time it persists unnoticed for years causing no health problems, C. albicans can turn into a dangerous microbe that causes serious diseases in many organs, including the urinary tract, lungs and brain.

30 Jul 2025

Bacteria use amyloids as molecular armor against predators

Amyloids are perhaps best known as a key driver of Alzheimer's disease.

30 Jul 2025

New platform predicts antibiotic resistance before it hits the clinics

Multidrug resistant bacteria kill five million people each year, with newly resistant germs emerging faster than scientists can develop treatments.

30 Jul 2025

New genetic mutation linked to highly invasive Streptococcus pyogenes infections

A group of researchers led by The University of Osaka have identified a novel genetic mutation in Streptococcus pyogenes, a common bacterium which causes strep throat, significantly associated with severe invasive infections.

30 Jul 2025

Gut microbial metabolites restore hormone-producing cells in obesity

New research from scientists at the Marshall University Joan C. Edwards School of Medicine reveals that certain gut microbial byproducts may hold promise as a novel therapy for obesity-associated metabolic complications by restoring critical hormone-producing cells in the intestine.

29 Jul 2025

Centauri Therapeutics receives an additional $5.1 M from CARB-X to progress ABX-01 lead compound to first in human clinical trials

Centauri Therapeutics Limited ('Centauri'), an immunotherapy company with a unique and proprietary platform technology applicable across a wide range of therapeutic indications, announced today that CARB-X (Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator) has provided an additional $5.1 M in funding for the development of their lead compound.

29 Jul 2025

Gut mycobiota could help predict disability in multiple sclerosis

Gut fungal communities may impact multiple sclerosis severity, offering new insights into MS pathogenesis and potential microbiome-based treatment strategies.

29 Jul 2025

What’s better for your gut: lean beef or chicken? Science weighs in

A crossover trial in healthy young adults found that both lean chicken and beef diets reduced gut microbial richness, but only chicken caused significant diversity loss. The study highlights that lean local beef may have a milder impact on the gut microbiome than chicken.

29 Jul 2025

How a leaky gut could be putting your heart at risk

Researchers reviewed recent studies showing that gut dysbiosis contributes to heart failure by weakening the gut barrier, enabling harmful metabolites like TMAO to trigger inflammation and cardiac damage. The review highlights a bidirectional “gut-heart axis” and points to new avenues for dietary and microbial therapies.

28 Jul 2025

Study maps RNA shape-shifting mechanisms in human and bacterial cells

Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures.

28 Jul 2025

Bacterial self-defense may hold clues to tackling antibiotic resistance

Researchers at the University of Southampton have worked out how bacteria defend themselves against viruses called phages and the new insights could be key to tackling antibiotic resistance.

28 Jul 2025

New swallowable sensor pill reveals gut inflammation with a simple color change

Researchers have developed an ingestible biosensor pill (PRIM) that detects intestinal inflammation by releasing a blue dye in response to elevated reactive oxygen species, providing a simple, at-home visual indicator.

27 Jul 2025

Low-gluten diets disrupt gut health by depleting key bacteria

Long-term gluten reduction may disrupt gut microbiota balance, reducing beneficial bacteria and increasing ethanol, linked to inflammation and metabolic risks.

24 Jul 2025

Gut bacteria send direct signals to the brain to stop you from overeating

Researchers have discovered a novel gut-brain sensory circuit in mice where specialized colonic cells sense bacterial flagellin and rapidly suppress feeding via the vagus nerve. This "neurobiotic sense" operates independently of immune pathways, revealing a direct neural mechanism for microbiota-host communication.

24 Jul 2025