Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Ochsner Health study highlights benefits of combination therapy for cardiovascular risks

Ochsner Health Medical Director for Cardiac Rehabilitation and Preventive Cardiology, Carl J. "Chip" Lavie, Jr., MD, recently co-authored a groundbreaking research study featured in the prestigious Mayo Clinic Proceedings highlighting the comparative efficacy of lipid-lowering therapies for reducing cardiovascular risks and led by Maciej Banach, MD,PhD from Poland and leader of the International Lipid Expert Panel ( ILEP).

25 Mar 2025

Targeting PCSK9 and APOA4 for the treatment of TMAO-induced cholelithiasis

Cholesterol synthesis and gallstone formation are promoted by trimethylamine-N-oxide (TMAO), a derivative of trimethylamine, which is a metabolite of gut microbiota.

25 Mar 2025

Ketogenic diet reverses obesity-linked biological aging by over 6 years

Obesity speeds up biological aging at the molecular level, but this study finds that a very-low-calorie ketogenic diet (VLCKD) can significantly reverse this effect.

24 Mar 2025

A pecan a day keeps bad cholesterol away

Daily consumption of 57g of pecans for 12 weeks improved cholesterol profiles and diet quality in adults at risk of cardiometabolic disease, without affecting vascular health. Replacing typical snacks with pecans led to higher intake of healthy fats and fiber, and reduced carbohydrate consumption.

24 Mar 2025

Red wine lowers bad cholesterol but doesn’t improve overall heart health

Moderate red wine consumption is linked to a small but significant reduction in LDL cholesterol, according to a systematic review and meta-analysis of 33 studies. However, the study found no consistent effects on HDL, triglycerides, total cholesterol, or fibrinogen.

24 Mar 2025

Combination therapy could prevent thousands of cardiovascular deaths

The largest analysis to examine the best way to lower levels of 'bad' cholesterol in patients with blocked arteries shows that they should immediately be given a combination of a statin and another drug called ezetimibe, rather than statins alone.

24 Mar 2025

Sticking to Life’s Essential 8 slashes cancer risk, major study shows

Long-term adherence to the American Heart Association’s “Life’s Essential 8” lifestyle score significantly reduces the risk of overall and site-specific cancers. Stable high LE8 scores over four years were linked to notably lower risks of lung, breast, liver, and colorectal cancers in a large Chinese cohort study.

23 Mar 2025

Duke-NUS and NUS Medicine launch first-ever joint center to drive metabolomics research

In a strategic move for medical research and innovation, Duke-NUS Medical School and the National University of Singapore Yong Loo Lin School of Medicine (NUS Medicine) have launched the Systems Metabolomics Centre (SysMeC), their first-ever joint research center.

22 Mar 2025

Oophorectomy linked to higher risk of heart failure in women

Women of childbearing age who had both ovaries removed, in a procedure called bilateral oophorectomy, were more likely to develop heart failure later in life, according to a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

20 Mar 2025

Strawberries enhance brain speed and heart health, but cognitive benefits remain unclear

Strawberries may modestly enhance processing speed and lower systolic blood pressure in older adults, but they do not significantly improve overall cognitive function or vascular health.

19 Mar 2025

Australian scientists redefine dietary fiber classification for better health benefits

Australian food scientists have reclassified dietary fibers – beyond just soluble and insoluble – to better guide nutritional decisions and drive targeted health food products.

19 Mar 2025

Electronic cigarettes may pose lower cardiovascular risks for people with HIV

Electronic cigarettes use may pose lower cardiovascular risks in people living with HIV compared to tobacco cigarette use, new UCLA-led research shows.

19 Mar 2025

AI predicts biological aging using steroid pathways

Researchers discuss a novel method to predict biological aging using a deep neural network based on pathways of steroidogenesis.

19 Mar 2025

FDA-approved drug for chronic kidney disease may help mitigate antibiotic resistance

Increased antibiotic use can lead, seemingly paradoxically, to more problematic infections, as the bacteria evolve to resist the treatment.

18 Mar 2025

Lifestyle and health factors have greater impact on cardiovascular risk in women than men

Lifestyle and health factors that are linked with heart disease appear to have a greater impact on cardiovascular risk in women than men, according to a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

18 Mar 2025

Cannabis use found to raise heart attack risk among younger adults

Marijuana is now legal in many places, but is it safe? Two new studies add to mounting evidence that people who use cannabis are more likely to suffer a heart attack than people who do not use the drug, even among younger and otherwise healthy adults.

18 Mar 2025

Keto controversy? Experts say it’s here to stay

Low-carb and ketogenic diets offer sustainable solutions for chronic disease, enhancing metabolic health and supporting weight loss through dietary changes.

18 Mar 2025

Study shows impact of statins and aspirin on muscle health in smokers

For current and former smokers, statins may reduce the amount of chest muscle loss, while aspirin may contribute to increased chest muscle loss, according to a new study.

13 Mar 2025

How gut health shapes heart disease risk — and what you can do about it

A new review highlights how gut microbiome imbalances contribute to cardiovascular disease by altering short-chain fatty acids, TMAO, and inflammatory pathways. The study emphasizes the potential of prebiotics, probiotics, and dietary changes to restore gut health and reduce heart disease risk.

13 Mar 2025