Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

COVID-19 was initially described as lung inflammation, or pneumonia, in older adults. However, we now know that SARS-CoV-2 infections can cause a wide range of symptoms in people of all ages, ranging from no symptoms at all to systemic inflammation and even death.

27 May 2021

Researchers to conduct Phase 1 gene therapy trial to treat Alzheimer's disease

The National Institute on Aging (NIA), part of the National Institutes of Health, has awarded a $5 million grant to researchers at University of California San Diego School of Medicine to conduct a first-in-human Phase 1 clinical trial of a gene therapy for treating Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

26 May 2021

Newly identified small molecule can be used to rejuvenate the brain, counteract memory loss

Alzheimer's disease is the main cause of dementia and current therapeutic strategies cannot prevent, slow down or cure the pathology.

25 May 2021

Researchers use special "micro-grid" recording device to measure hippocampus activity

Researchers at UC San Francisco have observed a new feature of neural activity in the hippocampus - the brain's memory hub - that may explain how this vital brain region combines a diverse range of inputs into a multi-layered memories that can later be recalled.

17 May 2021

Study examines a pathway responsible for the formation of tau tangles in the brain

Since the discovery of Alzheimer's disease over a century ago, two hallmarks of the devastating illness have taken center stage.

12 May 2021

LLNL-developed thin-film electrodes generate never-before-seen recordings of brain activity

Thin-film electrodes developed at Lawrence Livermore National Laboratory have been used in human patients at the University of California, San Francisco, generating never-before-seen recordings of brain activity in the hippocampus, a region responsible for memory and other cognitive functions.

12 May 2021

New implantable system can manipulate brain signals and suppress pathological coupling

As researchers learn more about the brain, it has become clear that responsive neurostimulation is becoming increasingly effective at probing neural circuit function and treating neuropsychiatric disorders, such as epilepsy and Parkinson's disease.

10 May 2021

Brain imaging study reveals patterns in individuals with sensory processing sensitivity

You know that raw overwhelm people have been reporting after months of a pandemic, compounded by economic issues and social unrest? Does fatigue and compulsive social media scrolling strike a familiar chord?

5 May 2021

Researchers use gene therapy to prevent learning, memory loss in Alzheimer's mouse model

Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer's disease (AD), a key step toward eventually testing the approach in humans with the neurodegenerative disease.

5 May 2021

IBEC researchers discover the neural mechanism of autonomous learning

Thanks to the so-called deep learning, a subset of artificial intelligence (AI) algorithms inspired by the brain, machines can match human performance in perception and language recognition and even outperform humans in certain tasks. But do these synthetic biologically inspired systems learn in the same way that we do?

3 May 2021

High-powered MRI detects subtle differences in the hippocampus of people with Down syndrome

Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome (DS), researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals and other institutions detected subtle differences in the structure and function of the hippocampus--a region of the brain tied to memory and learning.

29 Apr 2021

Neural implant can help monitor activity in multiple brain regions at the same time

How do different parts of the brain communicate with each other during learning and memory formation? A new study by researchers at the University of California San Diego takes a first step at answering this fundamental neuroscience question.

27 Apr 2021

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer's disease in mice.

22 Apr 2021

Study identifies how SARS-CoV-2 enters and infects the brain

A recent preclinical study led by Anja Kipar of the University of Zurich and the University of Liverpool found evidence of the virus infecting and eventually provoking cell death in microglia and immune cells — but not neurons. The viral-induced apoptosis in these brain cells may explain why some long-haulers experience ‘brain fog’ months after recovery.

21 Apr 2021

Protein-coding gene may worsen tau protein tangles associated with Alzheimer's

In a new paper published in Nature Communications, Mayo Clinic researchers and collaborators report the protein-coding gene SERPINA5 may worsen tau protein tangles, which are characteristic of Alzheimer's disease, and advance disease.

19 Apr 2021

New study sheds light on complex brain process that helps learn and form new memories

Making memories involves more than seeing friends or taking photos. The brain constantly adapts to new information and stores memories by building connections among neurons, called synapses. How neurons do this--reaching out arm-like dendrites to communicate with other neurons--requires a ballet of genes, signaling molecules, cellular scaffolding and protein-building machinery.

19 Apr 2021

SARS-CoV-2 does not directly infect the brain but can inflict neurological damage

SARS-CoV-2, the virus that causes COVID-19, likely does not directly infect the brain but can still inflict significant neurological damage, according to a new study from neuropathologists, neurologists, and neuroradiologists at Columbia University Vagelos College of Physicians and Surgeons.

17 Apr 2021

Hippocampus News and Research

Further Reading

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

Researchers to conduct Phase 1 gene therapy trial to treat Alzheimer's disease

Newly identified small molecule can be used to rejuvenate the brain, counteract memory loss

Researchers use special "micro-grid" recording device to measure hippocampus activity

Study examines a pathway responsible for the formation of tau tangles in the brain

LLNL-developed thin-film electrodes generate never-before-seen recordings of brain activity

New implantable system can manipulate brain signals and suppress pathological coupling

Brain imaging study reveals patterns in individuals with sensory processing sensitivity

Researchers use gene therapy to prevent learning, memory loss in Alzheimer's mouse model

IBEC researchers discover the neural mechanism of autonomous learning

High-powered MRI detects subtle differences in the hippocampus of people with Down syndrome

Neural implant can help monitor activity in multiple brain regions at the same time

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Study identifies how SARS-CoV-2 enters and infects the brain

Protein-coding gene may worsen tau protein tangles associated with Alzheimer's

New study sheds light on complex brain process that helps learn and form new memories

SARS-CoV-2 does not directly infect the brain but can inflict neurological damage

Engaging in household chores may be beneficial for brain health in older adults

Study shows how alcohol may affect the brain, offers potential treatments for alcohol misuse

Stem cells of the nervous system age rapidly, shows study

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