Genome News and Research

RSS

Study points toward earlier and more accurate detection of ALS

A new study applying multi-omics techniques and machine learning identified 33 plasma proteins that differ significantly in patients with amyotrophic lateral sclerosis (ALS).

29 Sep 2025

AI tool accurately distinguishes between glioblastoma and primary central nervous system lymphoma

A Harvard Medical School–led research team has developed an AI tool that can reliably tell apart two look-alike cancers found in the brain but with different origins, behaviors, and treatments.

29 Sep 2025

Cancer cell nuclear hypertrophy can suppress metastasis

In tissue biopsies, cancer cells are frequently observed to have nuclei (the cell's genetic information storage) larger than normal.

29 Sep 2025

Study shows how early-life epigenetic 'memory' can influence adult brain inflammation

Why do some people remain healthy through childhood yet become more vulnerable to brain disorders such as dementia later in life? A KAIST (President Kwang Hyung Lee) -led team has uncovered a key part of the answer: a developmental 'switch' in astrocytes—the brain's most abundant support cells that shapes how strongly the brain's immune system reacts in adulthood.

25 Sep 2025

Study explains how genetics and lifestyle combined to keep a 117-year-old healthy

Scientists conducted a multiomics study of the world’s oldest verified person (117 years), uncovering protective genetic, immune, metabolic, microbiome, and epigenetic traits that supported her exceptional longevity. These findings highlight how aging and disease may, under rare circumstances, be decoupled.

25 Sep 2025

Alcohol raises dementia risk at every level of drinking, genetic study shows

Researchers using two major cohorts and Mendelian randomization found that alcohol consumption, whether light or heavy, raises the risk of dementia. Genetic evidence shows no safe level of drinking, challenging the belief that moderate intake protects brain health.

25 Sep 2025

Tiny DNA junctions provide feedback to control genetic crossovers

Every new life begins after a genetic shuffle. When organisms make eggs or sperm, maternal and paternal chromosomes pair up and swap pieces of DNA in a process called crossing over.

25 Sep 2025

Genetic modification enhances "living drugs" for blood cancers

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, with a "chimeric antigen receptor" (CAR) enables them to specifically recognize and attack cancer cells.

25 Sep 2025

Researchers uncover how chromosome crossovers protect fertility

When a woman becomes pregnant, the outcome of that pregnancy depends on many things - including a crucial event that happened while she was still growing inside her own mother's womb.

24 Sep 2025

Blocking iron-regulating enzyme triggers cancer cell death in multiple myeloma

Researchers at Duke University have shown that blocking an enzyme involved in iron regulation not only kills multiple myeloma cancer cells, but also increases the effectiveness of current therapies against the disease.

24 Sep 2025

Scientists outline how future therapies could change type 1 diabetes care

Researchers writing in The Lancet review breakthroughs in type 1 diabetes treatment, from immunotherapies that delay onset to stem-cell β-cell replacement and automated insulin delivery. They stress that equitable access, validated surrogate endpoints, and scalable technologies are crucial for lasting impact.

24 Sep 2025

New screening method boosts efficiency and accuracy of CAST genome editing

Natural systems such as CRISPR-associated transposons (CASTs) offer a targetable, one-step way to edit genomes.

23 Sep 2025

Drinking any amount of alcohol may raise dementia risk

Drinking any amount of alcohol likely increases the risk of dementia, suggests the largest combined observational and genetic study to date, published online in BMJ Evidence Based Medicine.

23 Sep 2025

Study reveals a new oncogenic role of NBL1 in ovarian cancer metastasis

Ovarian cancer (OC), one of the three most common gynecological malignancies, is characterized by low early detection rates and poor prognosis.

23 Sep 2025

Scientists uncover 53 genetic clues that shape math ability beyond IQ

Researchers uncovered 53 genetic loci linked to quantitative ability, distinguishing it from general intelligence and non-cognitive skills. The study highlights brain pathways in axon guidance, synaptic signaling, and mRNA splicing as biological underpinnings of math-related ability.

22 Sep 2025

UC Davis wins NSF grants to advance AI-driven protein engineering

Two projects at the University of California, Davis, that use artificial intelligence to design and engineer proteins for industrial and health applications have been funded by the U.S. National Science Foundation (NSF).

19 Sep 2025

Genetic study reveals how Anopheles funestus adapts to malaria control

New research into the genetics of Anopheles funestus (An. funestus), one of the most neglected but prolific malaria-transmitting mosquitoes in Africa, has revealed how this species is evolving in response to malaria control efforts.

18 Sep 2025

Innovative RNA editing offers hope beyond CRISPR

Genetic editing holds promise to treat incurable diseases, but the most popular method - CRISPR - sometimes does more harm than good.

18 Sep 2025

Enhanced Genomics extends Series A funding to USD $19 million to drive development of therapeutics pipeline

Enhanced Genomics ('Enhanced'), the biotechnology company pioneering 3D multi-omics to rapidly identify high-confidence, genetically validated drug targets for common diseases, today announced it has completed a financing round, extending its total Series A funding to $19 million.

17 Sep 2025

Researchers uncover how HIV-1 uses RNA:DNA hybrids to integrate into the genome

Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human genome.

16 Sep 2025