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Reprogramming T cells to overcome tumor challenges

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and their collaborators demonstrated a remarkable ability to boost the immune system's fight against cancer, showing promise for improving patient outcomes in difficult-to-treat malignancies.

10 Mar 2025

Eating ultra-processed foods harms your gut—here’s how inflammation takes hold

Ultra-processed foods disrupt gut microbiome balance, causing inflammation, reduced microbial diversity, and increased gut permeability. This microbiome imbalance contributes to chronic diseases including diabetes, IBD, cancer, and neurological disorders.

6 Mar 2025

St. Jude researchers improve brain disease diagnosis with PET imaging and ALS drug

Positron emission tomography (PET) is a nuclear imaging technique used to diagnose conditions such as cancer. An innovative advance from scientists at St. Jude Children's Research Hospital is enhancing the technique's ability to check for signs of neurological disease.

6 Mar 2025

Feeding strategies in preterm infants do not alter brain growth or cognition

Early nutrition in very preterm infants does not significantly impact brain growth or neurodevelopment when following standardized clinical guidelines, despite initial unadjusted associations.

5 Mar 2025

Exploring the relationship between non-coding RNAs and oxidative stress in cancer progression

A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that drive tumor development.

5 Mar 2025

Iron dysregulation linked to long COVID development

Problems with iron levels in the blood and the body's ability to regulate this important nutrient as a result of SARS-CoV-2 infection could be a key trigger for long COVID, new research has discovered.

5 Mar 2025

Millions suffer from lack of access to safe medical oxygen globally

Six out of every ten people globally lack access to safe medical oxygen, resulting in hundreds of thousands of preventable deaths each year and reducing quality of life for millions more, an international report co-authored by the University of Auckland has found.

4 Mar 2025

Targeting mitochondrial DNA integrity for cardiac protection after injury

Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury.

4 Mar 2025

Alpha particle therapy offers new hope for neuroendocrine tumors

In a comprehensive Genomic Press Viewpoint (review) article, researchers are shining a spotlight on a revolutionary approach to tackling neuroendocrine tumors (NETs), a rare but increasingly prevalent form of cancer.

4 Mar 2025

Study reveals key cause of ventilator-induced lung injury

A new study from Tulane University suggests that repeated collapse and reopening of tiny alveoli-air sacs in the lungs essential for breathing-during mechanical ventilation may cause microscopic tissue damage, playing a key role in ventilator-related injuries that contribute to thousands of deaths annually.

3 Mar 2025

Novel adipose tissue biofabrication approach paves the way for enhanced skin regeneration

The adipose tissue, which serves as an endocrine organ, releases various molecules that regulate the repair of other damaged tissues, including the skin.

3 Mar 2025

Pioneering the world’s first CRISPR medicine for sickle cell disease

When Vijay Sankaran was an MD-PhD student at Harvard Medical School in the mid-2000s, one of his first clinical encounters was with a 24-year-old patient whose sickle cell disease left them with almost weekly pain episodes.

3 Mar 2025

Early CPAP treatment may reduce Parkinson's disease risk in people with sleep apnea

People with obstructive sleep apnea have an increased risk of Parkinson's disease, but if started early enough, continuous positive airway pressure (CPAP) may reduce that risk, according to a preliminary study released today, March 2, 2025, that will be presented at the American Academy of Neurology's 77th Annual Meeting taking place April 5–9, 2025, in San Diego and online.

2 Mar 2025

Researchers uncover how brain tumors reprogram neutrophils to hinder cancer treatment

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling further tumor growth.

2 Mar 2025

Understanding the benefits and risks of hyperbaric oxygen therapy

Hyperbaric oxygen therapy is well known for treating scuba and deep-sea divers affected by the rapid change in pressure around them. But did you know that HBOT is also used to treat a variety of other health problems, including carbon monoxide poisoning and diabetic foot ulcers?

28 Feb 2025