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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Landmark study maps mutational landscape of triple-negative breast cancer in African American women

Triple-negative breast cancer (TNBC), the deadliest breast cancer subtype, disproportionately affects African American women – but until now, they were underrepresented in genomic studies aimed at identifying the genetic mutations driving the disease.

1 Sep 2025

Why metformin could protect the brain by rewiring mitochondria

Metformin boosts human oligodendrocyte differentiation and myelination across stem-cell, organoid, and chimera models. The study links these effects to mitochondrial metabolic shifts, supporting its potential as a therapy for multiple sclerosis.

1 Sep 2025

Phase II trial finds zilebesiran lowers systolic blood pressure in patients with uncontrolled hypertension

Among individuals with cardiovascular disease or high cardiovascular risk and uncontrolled hypertension on multiple anti-hypertensive agents, a single subcutaneous dose of zilebesiran 300 mg led to a 5-mmHg reduction in systolic blood pressure at Month 3 compared with placebo, a difference that did not reach statistical significance.

1 Sep 2025

Discovery of mitochondrial microprotein opens path to obesity and aging therapies

Like bees breathing life into gardens, providing pollen and making flowers blossom, little cellular machines called mitochondria breathe life into our bodies, buzzing with energy as they produce the fuel that powers each of our cells.

29 Aug 2025

Transcription factors SP5 and SP8 regulate primary cilia formation in embryos

Some might say it looks like a finger. Others might see a worm. Scientists in the field often liken it to an antenna.

29 Aug 2025

Exploring the untapped potential of DNA glycosylation

Recent advancements in glycobiology have challenged the traditional understanding of molecular interactions, and a new study published in Engineering titled "Can DNA be glycosylated?" by Wei Wang further explores this emerging field.

29 Aug 2025

Male and female bovine embryos show distinct development paths

Cornell researchers have uncovered the genetic triggers that cause male and female bovine embryos to develop differently, as early as seven to eight days after fertilization.

29 Aug 2025

Disrupting protein quality control slows tumor growth in pediatric rhabdomyosarcoma

A new research paper was published in Volume 16 of Oncotarget on August 29, 2025, titled "In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma."

29 Aug 2025

Signaling mechanisms driving olfactory neurogenesis in zebrafish

Cellular differentiation of stem cells into specialized cells requires many steps, including division, to create more cells; fate determination, which is a commitment to a specific lineage or developmental path; and migration, to integrate the cell into its final location.

29 Aug 2025

Stress in mothers causes eczema in newborn mice through immune cell changes

Maternal prenatal stress in mice disrupts fetal mast cell programming, triggering eczema-like skin inflammation and heightened sensitivity after birth. The findings reveal how corticosterone-driven immune and neuronal changes in utero may set the stage for pediatric eczema risk.

28 Aug 2025

Research sheds new light on depression’s biological roots

Researchers at McGill University and the Douglas Institute have identified two specific types of brain cells that are altered in people with depression.

28 Aug 2025

Researchers develop novel exosome-based therapeutic agent for treating traumatic CNS injuries

Traumatic injuries of the central nervous system (CNS)-such as traumatic brain injury (TBI) and traumatic spinal cord injury (SCI)-are characterized by oxidative damage and neuroinflammation.

28 Aug 2025

Single gene discovery reveals key sex difference in immune response

A new study has uncovered a key difference between the immune system of males and females - and it comes down to a single gene.

28 Aug 2025

Longitudinal study reveals how GLP-2 analog therapy transforms the intestinal environment

Researchers from Japan discover that glucagon-like peptide-2 (GLP-2) analogs can deeply and beneficially reshape the intestinal environment.

27 Aug 2025

Yale scientists boost mRNA vaccine power with new technology

Messenger RNA, or mRNA, vaccines entered the public consciousness when they were introduced during the COVID-19 pandemic, and both Pfizer-BioNTech and Moderna used the technology in developing their highly effective vaccines to fight the virus.

27 Aug 2025

AUF1 protein shown to suppress cellular senescence and altered metabolism

A new research paper was published in Volume 17, Issue 7 of Aging (Aging-US) on July 24, 2025, titled "RNA-binding protein AUF1 suppresses cellular senescence and glycolysis by targeting PDP2 and PGAM1 mRNAs."

27 Aug 2025

Shared gene signatures reveal metabolic dysfunction in liver cirrhosis and acute-on-chronic liver failure

Chronic liver cirrhosis (LC) and acute-on-chronic liver failure (ACLF) are interconnected hepatic disorders associated with substantial morbidity and mortality.

27 Aug 2025

Groundbreaking method captures microbial memory at the earliest stages of colony growth

Bacteria aren't just mindless microbes. New research from the Hebrew University of Jerusalem reveals that single bacterial cells can carry a "memory" of their past environments-passing it down through generations-before eventually forgetting.

26 Aug 2025

New method uncovers how extracellular vesicles impact immune response in cancer

Certain types of biochemical processes can impair the immune system's ability to recognize and kill cancer cells. Purdue University's W. Andy Tao and his associates have developed a new way to study these processes.

26 Aug 2025

Diabetes-altered blood particles suppress immune defense in breast cancer

People with type 2 obesity-driven diabetes tend to have more aggressive breast cancers, but no one knows exactly why.

26 Aug 2025

RNA News and Research

Further Reading

Landmark study maps mutational landscape of triple-negative breast cancer in African American women

Why metformin could protect the brain by rewiring mitochondria

Phase II trial finds zilebesiran lowers systolic blood pressure in patients with uncontrolled hypertension

Discovery of mitochondrial microprotein opens path to obesity and aging therapies

Transcription factors SP5 and SP8 regulate primary cilia formation in embryos

Exploring the untapped potential of DNA glycosylation

Male and female bovine embryos show distinct development paths

Disrupting protein quality control slows tumor growth in pediatric rhabdomyosarcoma

Signaling mechanisms driving olfactory neurogenesis in zebrafish

Stress in mothers causes eczema in newborn mice through immune cell changes

Research sheds new light on depression’s biological roots

Researchers develop novel exosome-based therapeutic agent for treating traumatic CNS injuries

Single gene discovery reveals key sex difference in immune response

Longitudinal study reveals how GLP-2 analog therapy transforms the intestinal environment

Yale scientists boost mRNA vaccine power with new technology

AUF1 protein shown to suppress cellular senescence and altered metabolism

Shared gene signatures reveal metabolic dysfunction in liver cirrhosis and acute-on-chronic liver failure

Groundbreaking method captures microbial memory at the earliest stages of colony growth

New method uncovers how extracellular vesicles impact immune response in cancer

Diabetes-altered blood particles suppress immune defense in breast cancer

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