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New variant may not have changed COVID-19 pandemic course in UK, says study

A new study examines the effect of the new "Kent variant" of SARS-CoV-2 on the epidemic course within the UK.

19 Mar 2021

Study examines efficacy of Pfizer-BioNTech mRNA COVID-19 vaccine across demographic groups

A new study examines data from Israel's vaccination campaign to assess the efficacy of the Pfizer-BioNTech mRNA vaccine across different demographics.

19 Mar 2021

Study shows how ACE2 mutations influence SARS-CoV-2 spike binding in humans and animals

Researchers at the University of Wisconsin–Madison aimed to better understand how SARS-CoV-2 interacts with various mammalian angiotensin-converting enzyme 2 (ACE2) receptors. This way, they can identify the factors that influence intra- and cross-species virus transmission.

18 Mar 2021

SARS-CoV-2 vaccination should be carefully targeted towards certain groups, say researchers

Researchers in the UK have provided important insights into the impact that vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – may have on infection rates, disease prevalence and immune escape by the virus.

18 Mar 2021

New study provides comparative analysis of twelve COVID-19 vaccines

A new study by Novateur Ventures provides a comparative analysis of twelve COVID-19 Vaccines that had initiated or announced the Phase III clinical trial stage by early November 2020.

18 Mar 2021

Study highlights the importance of protecting elderly people from COVID-19 reinfection

Most people who have had COVID-19 are protected from catching it again for at least six months, but elderly patients are more prone to reinfection, according to research published in The Lancet.

18 Mar 2021

New evidence supports ivermectin use in children weighing less than fifteen kilograms

Millions of children weighing less than 15kg are currently denied access to Ivermectin treatment due to insufficient safety data being available to support a change to the current label indication.

18 Mar 2021

New high-throughput system for testing drug candidates to treat brain diseases

On the basis of a license agreement with the German Center for Neurodegenerative Diseases (DZNE) and the Leibniz Institute of Polymer Research Dresden (IPF), the Dresden-based start-up "Neuron-D GmbH" is developing a high-throughput system for testing drug candidates to treat neurodegenerative diseases.

18 Mar 2021

Progesterone therapy may improve clinical outcomes for male COVID-19 patients

COVID-19 disproportionately affects men compared with women, raising the possibility that a hormone like progesterone may improve clinical outcomes for certain hospitalized men with the disease.

18 Mar 2021

Using nanoparticles for efficient delivery of antimicrobial peptides to treat deep infections

Announcing a new article publication for BIO Integration journal. In this review article the authors Yingxue Deng, Rui Huang, Songyin Huang and Menghua Xiong from South China University of Technology, Guangzhou, Guangdong, P. R. China and Sun Yat-sen University, Guangzhou, Guangdong, P. R. China discuss how nanoparticles enable efficient delivery of antimicrobial peptides for the treatment of deep infections.

18 Mar 2021

Novel cancer-fighting gene therapy enters phase I clinical trial

Researchers from the MDC and Charité have developed a new gene therapy based around a special T-cell receptor that helps the immune system effectively recognize and fight cancer cells.

18 Mar 2021

SARS-CoV-2 variants with E484K mutation show mRNA vaccine-induced antibody evasion

A recent study found that the Pfizer-BioNTech mRNA vaccine had limited efficacy in identifying mutated receptor-binding domains (RBDs) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein similar to the B.1.351 and P.1 variants.

18 Mar 2021

How resistant is the SARS-CoV-2 Brazilian variant to antibodies?

Researchers based at the University of Oxford, UK, have shown that the P.1 Brazilian variant of SARS-CoV-2 is less resistant to natural or vaccine acquired antibody responses than the B.1.351, South African, variant, despite sharing convergent mutations.

18 Mar 2021

Can vaccine evading SARS-CoV-2 variants be restricted by prioritized vaccine rollout?

A new study discusses the question of how vaccine priority is affected by the possibility of vaccine escape.

18 Mar 2021

Do Artemisia annua L. compounds have SARS-CoV-2 antiviral potential?

Caused by SARS-CoV-2, the ongoing COVID-19 pandemic has led to over 121.2 million cases and over 2.6 million deaths worldwide. An interesting new study examines the potential antiviral activity of compounds present in the plant Artemisia annua L.

18 Mar 2021

GMP-Ready Helper Plasmids for AAV Production

Manufactured in dedicated clean-rooms with mandated changeovers before new production cycles - AMSBIO introduces new pHelper-Kan plasmid DNA optimized for Adeno-Associated Virus (AAV) manufacturing.

18 Mar 2021

New way to enhance treatment outcomes for breast cancer

Breast cancer is the most common cancer in women worldwide and the second most common cancer overall. Although it can now be treated with drugs, many of these drugs mysteriously stop working after some time, causing a relapse.

18 Mar 2021

Study characterizes shifting neoantigen burden between primary and metastatic tumors within HNSCC

Oncotarget published "Genomic and neoantigen evolution from primary tumor to first metastases in head and neck squamous cell carcinoma" which reported that prior work has characterized changes in the mutation burden between primary and recurrent tumors; however, little work has characterized the changes in neoantigen evolution.

18 Mar 2021

Vaccinating the elderly first for COVID-19 saves most lives

A short paper authored by Goldstein, Cassidy, and Wachter, recently published online in the journal Proceedings of the National Academy of Sciences of the United States of America (PNAS), demonstrates mathematically that vaccinating the oldest first, in fact, ultimately saves both the most lives and the most life-years.

17 Mar 2021

Air purification technologies to combat SARS-CoV-2

The onset of the COVID-19 pandemic had people sharing an array of strategies for disinfection and disease prevention.

17 Mar 2021

Efficacy News and Research

New variant may not have changed COVID-19 pandemic course in UK, says study

Study examines efficacy of Pfizer-BioNTech mRNA COVID-19 vaccine across demographic groups

Study shows how ACE2 mutations influence SARS-CoV-2 spike binding in humans and animals

SARS-CoV-2 vaccination should be carefully targeted towards certain groups, say researchers

New study provides comparative analysis of twelve COVID-19 vaccines

Study highlights the importance of protecting elderly people from COVID-19 reinfection

New evidence supports ivermectin use in children weighing less than fifteen kilograms

New high-throughput system for testing drug candidates to treat brain diseases

Progesterone therapy may improve clinical outcomes for male COVID-19 patients

Using nanoparticles for efficient delivery of antimicrobial peptides to treat deep infections

Novel cancer-fighting gene therapy enters phase I clinical trial

SARS-CoV-2 variants with E484K mutation show mRNA vaccine-induced antibody evasion

How resistant is the SARS-CoV-2 Brazilian variant to antibodies?

Can vaccine evading SARS-CoV-2 variants be restricted by prioritized vaccine rollout?

Do Artemisia annua L. compounds have SARS-CoV-2 antiviral potential?

GMP-Ready Helper Plasmids for AAV Production

New way to enhance treatment outcomes for breast cancer

Study characterizes shifting neoantigen burden between primary and metastatic tumors within HNSCC

Vaccinating the elderly first for COVID-19 saves most lives

Air purification technologies to combat SARS-CoV-2

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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