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Study characterizes anti-inflammatory effect of strawberry geranium on the skin

Strawberry geranium (Saxifraga stolonifera) has been used in Japan as a herbal medicine to treat wounds and swelling, and continues to be an ingredient in food and cosmetics.

23 Apr 2021

Contralateral esophagus sparing technique can prevent complication in lung cancer patients

For many patients with localized lung cancer (non-small-cell lung carcinoma and small cell lung carcinoma), high-dose radiation with concurrent chemotherapy is a potential cure. Yet this treatment can cause severe, acute inflammation of the esophagus (esophagitis) in about one in five patients, requiring hospitalization and placement of a feeding tube.

23 Apr 2021

Researchers perform cross-sectional analysis to understand the link between insomnia and anemia

A good night's sleep is essential for a healthy body and mind, for when we sleep is when the body resets, repairs, and refreshes itself. A lot of people, however, have trouble falling or staying asleep, a condition known as insomnia that affects up to 30% of the population.

23 Apr 2021

DNA vaccine candidate induces potent immunity, offers protective efficacy in non-human primate models

A synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV) developed at The Wistar Institute induced potent immune responses and afforded protective efficacy in non-human primate (NHP) models when given intradermally in abbreviated, low-dose immunization regimen.

23 Apr 2021

Celastrol shows potential anti-SARS-CoV-2 activity

A new study published on the bioRxiv* preprint server focuses on the in-silico predictions to repurpose existing drug compounds, that may have the ability to reverse the SARS-CoV-2 gene expression induced in host cells.

23 Apr 2021

Striking difference identified between mRNA vaccination vs. SARS-CoV-2 infection immune responses

A team of scientists from the United States has recently compared the immune response elicited by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vaccination. Their findings reveal that, unlike vaccination, natural SARS-CoV-2 infection is associated with a robust interferon response together with an induction of cytotoxic gene expression in peripheral blood lymphocytes. The study is currently available on the medRxiv* preprint server.

22 Apr 2021

Researchers discover molecule that provides dual protection against vascular inflammation

A multidisciplinary team of researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research (A*STAR) in Singapore discovered a new mitochondrial peptide called MOCCI that plays an important role in regulating inflammation of blood vessel and immunity.

22 Apr 2021

Clinical trial examines metabolic effects of natural compound NMN in people

A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to new research at Washington University School of Medicine in St. Louis.

22 Apr 2021

Changing the treatment paradigm for ‘cold’ tumors

Not all cancerous tumors are created equal. Some tumors, known as "hot" tumors, show signs of inflammation, which means they are infiltrated with T cells working to fight the cancer. Those tumors are easier to treat, as immunotherapy drugs can then amp up the immune response.

22 Apr 2021

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer's disease in mice.

22 Apr 2021

Developing nanoparticles to detect and kill multi-resistant pathogens

Multi-resistant pathogens are a serious and increasing problem in today's medicine. Where antibiotics are ineffective, these bacteria can cause life-threatening infections.

22 Apr 2021

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

Today, the U.S. Food and Drug Administration granted accelerated approval to Jemperli (dostarlimab) for treating patients with recurrent or advanced endometrial cancer that has progressed on or following prior treatment with a platinum-containing chemotherapy and whose cancers have a specific genetic feature known as dMMR (which contain abnormalities that affect the proper repair of DNA inside the cell), as determined by an FDA-approved test.

22 Apr 2021

UTHSC researchers receive $1.99 million to advance understanding of diabetes pathophysiology

The National Institute of Diabetes and Digestive and Kidney Diseases recently awarded a team of UTHSC researchers $1.99 million for their work to advance understanding of the pathophysiology of prediabetes, diabetes, and related complications.

22 Apr 2021

Doctors scramble to understand long Covid, but causes and prognosis are elusive

One night in March 2020, Joy Wu felt like her heart was going to explode. She tried to get up and fell down. She didn't recognize friends' names in her list of phone contacts. Remembering how to dial 9-1-1 took "quite a bit of time," she recalled recently.

22 Apr 2021

3D-printed anatomical finger model offers procedural guidance of trigger finger injections

Treatment of an injured or diseased joint may require precise insertion of a syringe needle -- musculoskeletal sonography can help guide clinicians as they drain fluid from arthritic knees or inject corticosteroids into trigger fingers.

22 Apr 2021

Study changes traditional views on atherosclerosis, offers new avenues for treatment

WHO Peter Libby, MD, cardiovascular medicine specialist at Brigham and Women's Hospital and the Mallinckrodt Professor of Medicine at Harvard Medical School; author of a new review paper published in Nature.

22 Apr 2021

Some COX inhibitors/NSAIDs increase COVID-19 severity

A startling new preprint research paper posted to the medRxiv server warns against the use of commonly used non-steroidal anti-inflammatory drugs (NSAIDs) belonging to the category of cyclooxygenase inhibitors (COX inhibitors) in patients with coronavirus disease 2019 (COVID-19).

22 Apr 2021

Metabolic testing of COVID-19 patients through skin imprints

There is, therefore, a great need to understand how the illness can be diagnosed using more convenient and inexpensive methods. A new study posted to the medRxiv preprint server reveals the potential role of skin imprints to test for biomarkers that indicate a diagnosis of COVID-19 in a non-invasive way.

22 Apr 2021

Pro-inflammatory diet may be associated with increased risk of testosterone deficiency in men

Consuming a diet high in pro-inflammatory foods - including foods that contain refined carbohydrates and sugar as well as polyunsaturated fats - may be associated with increased odds of developing testosterone deficiency among men, suggests a study in The Journal of Urology, Official Journal of the American Urological Association.

21 Apr 2021

AI-driven system for automatically detecting abnormalities on brain MRI could speed up care

An artificial intelligence-driven system that automatically combs through brain MRIs for abnormalities could speed care to those who need it most, according to a study published in Radiology: Artificial Intelligence.

21 Apr 2021

Inflammation News and Research

Study characterizes anti-inflammatory effect of strawberry geranium on the skin

Contralateral esophagus sparing technique can prevent complication in lung cancer patients

Researchers perform cross-sectional analysis to understand the link between insomnia and anemia

DNA vaccine candidate induces potent immunity, offers protective efficacy in non-human primate models

Celastrol shows potential anti-SARS-CoV-2 activity

Striking difference identified between mRNA vaccination vs. SARS-CoV-2 infection immune responses

Researchers discover molecule that provides dual protection against vascular inflammation

Clinical trial examines metabolic effects of natural compound NMN in people

Changing the treatment paradigm for ‘cold’ tumors

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Developing nanoparticles to detect and kill multi-resistant pathogens

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

UTHSC researchers receive $1.99 million to advance understanding of diabetes pathophysiology

Doctors scramble to understand long Covid, but causes and prognosis are elusive

3D-printed anatomical finger model offers procedural guidance of trigger finger injections

Study changes traditional views on atherosclerosis, offers new avenues for treatment

Some COX inhibitors/NSAIDs increase COVID-19 severity

Metabolic testing of COVID-19 patients through skin imprints

Pro-inflammatory diet may be associated with increased risk of testosterone deficiency in men

AI-driven system for automatically detecting abnormalities on brain MRI could speed up care

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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