Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Study links oral microbiome to cognitive function in older adults

The microbial ecosystems within our mouths may affect our cognitive function as we age, according to a study. Interventions such as prebiotics, including dietary nitrate, have potential for delaying cognitive decline.

28 Jan 2025

New diagnostic guidelines aim to distinguish common memory disorder from Alzheimer’s

LATE-NC diagnostic criteria improve differentiation from Alzheimer's, addressing challenges in memory-loss syndromes and guiding therapeutic interventions.

28 Jan 2025

Hebrew SeniorLife's Wolk Center achieves level 2 Age-Friendly Health System status

Hebrew SeniorLife, New England's largest nonprofit provider of senior health care and living communities and the only senior care organization affiliated with Harvard Medical School, announces that its Deanna and Sidney Wolk Center for Memory Health has been recognized by the Institute of Healthcare Improvement (IHI) as an Age-Friendly Health System, level 2, Committed to Care Excellence.

27 Jan 2025

Crick researchers identify key Y chromosome genes influencing sperm development

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice.

23 Jan 2025

Diagnostic guidelines released for limbic-predominant age-related TDP-43 encephalopathy

New guidelines will help doctors identify patients with a common memory-loss syndrome that is often misdiagnosed as Alzheimer's disease in older adults.

22 Jan 2025

Childhood epilepsy linked to late-onset brain amyloid disorders

Researchers from the University of Turku and Åbo Akademi University in Finland and the University of Wisconsin in the United States demonstrated that individuals who had childhood epilepsy have an increased accumulation of brain amyloid later in life, potentially predisposing them to late-onset brain amyloid disorders, such as Alzheimer's disease.

22 Jan 2025

Breakthrough discovery sheds light on how brain cells activate learning genes

A breakthrough study published today in the Journal of Neuroscience sheds new light on how brain cells relay critical information from their extremities to their nucleus, leading to the activation of genes essential for learning and memory.

21 Jan 2025

New insights into how cells clean and recycle waste

A recent study from Tata Institute of Fundamental Research, Mumbai, India has revealed new details about how our cells clean up and recycle waste.

21 Jan 2025

CDC report reveals COPD as the sixth leading cause of death in the U.S.

Chronic lower respiratory diseases, including chronic obstructive pulmonary disease (COPD), are the sixth leading cause of death in the United States, according to the U.S. Centers for Disease Control and Prevention (CDC).

21 Jan 2025

Antibiotics, antivirals, vaccines and anti-inflammatory drugs associated with reduced dementia risk

Antibiotics, antivirals, vaccinations and anti-inflammatory medication are associated with reduced risk of dementia, according to new research that looked at health data from over 130 million individuals.

21 Jan 2025

Benefits and risks of popular weight-loss drugs revealed

Demand for weight-loss medications sold under brand names such as Ozempic and Wegovy continues to surge, with a recent study reporting one in eight Americans has taken or is currently using the drugs to treat diabetes, heart disease or obesity.

20 Jan 2025

New approach combines two methods to study disordered proteins

Researchers of Mainz University and EMBL Hamburg present a new approach to determine the form of disordered proteins by using two different methods simultaneously in a single sample.

20 Jan 2025

Study reveals brain aging in sickle cell patients

Individuals with sickle cell disease – a chronic illness where misshapen, sticky blood cells clump together, reducing oxygen delivery to organs – are at a higher risk for stroke and resulting cognitive disability.

17 Jan 2025

New probes offer insight into cholesterol's role in Alzheimer's disease

The search for answers to Alzheimer's disease and other neurodegenerative disorders remains one of the most pressing goals in brain research. Maciej J. Stawikowski, Ph.D., an assistant professor of chemistry and biochemistry at Florida Atlantic University's Charles E. Schmidt College of Science, believes the key may lie in understanding how cholesterol and other lipids move through cells and affect their communication.

17 Jan 2025

Early brain changes in Huntington’s disease detected two decades before symptoms

Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's disease, finds a new study led by UCL researchers.

17 Jan 2025

Air pollution amplifies dementia risk in cardiometabolic disease patients - healthy habits can help

CMD patients face a 2x higher risk of dementia and MCI, but healthier lifestyles can counter air pollution's impact and reduce these risks.

16 Jan 2025

Xenon gas offers potential neuroprotective effects for Alzheimer's patients

Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research from Mass General Brigham and Washington University School of Medicine in St. Louis points to a novel-and noble-approach: using Xenon gas.

16 Jan 2025

Eating greater quantities of red meat may increase risk of dementia

Red meat consumption is an established risk factor for chronic conditions, including cardiovascular disease and type 2 diabetes.

15 Jan 2025

Spear Bio secures FDA breakthrough device designation for its novel pTau 217 blood test, advancing scalable solutions for early Alzheimer's disease diagnosis

Spear Bio Inc., a biotechnology company pioneering next-generation ultra-sensitive immunoassays, today announced that its pTau 217 blood test has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration (FDA).

From Spear Bio 15 Jan 2025

Study uncovers mechanism for cognitive improvement in dementia

A University of the Basque Country (UPV/EHU) study proves that the WIN55.212-2 drug protects the brain and reverses the initial cognitive damage caused by dementia, and explains how it works

15 Jan 2025

Alzheimer's Disease News and Research

Further Reading

Study links oral microbiome to cognitive function in older adults

New diagnostic guidelines aim to distinguish common memory disorder from Alzheimer’s

Hebrew SeniorLife's Wolk Center achieves level 2 Age-Friendly Health System status

Crick researchers identify key Y chromosome genes influencing sperm development

Diagnostic guidelines released for limbic-predominant age-related TDP-43 encephalopathy

Childhood epilepsy linked to late-onset brain amyloid disorders

Breakthrough discovery sheds light on how brain cells activate learning genes

New insights into how cells clean and recycle waste

CDC report reveals COPD as the sixth leading cause of death in the U.S.

Antibiotics, antivirals, vaccines and anti-inflammatory drugs associated with reduced dementia risk

Benefits and risks of popular weight-loss drugs revealed

New approach combines two methods to study disordered proteins

Study reveals brain aging in sickle cell patients

New probes offer insight into cholesterol's role in Alzheimer's disease

Early brain changes in Huntington’s disease detected two decades before symptoms

Air pollution amplifies dementia risk in cardiometabolic disease patients - healthy habits can help

Xenon gas offers potential neuroprotective effects for Alzheimer's patients

Eating greater quantities of red meat may increase risk of dementia

Spear Bio secures FDA breakthrough device designation for its novel pTau 217 blood test, advancing scalable solutions for early Alzheimer's disease diagnosis

Study uncovers mechanism for cognitive improvement in dementia

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