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Metabolic syndrome affects nearly four in ten US adults as rates climb in older and Black populations

A large NHANES analysis found that nearly four in ten US adults met criteria for metabolic syndrome between 2013 and 2023, with no statistically significant change in overall prevalence. However, prevalence rose significantly among adults aged 60 years and older and among non-Hispanic Black individuals, alongside a significant non-linear increase in hypertriglyceridemia.

14 Dec 2025

Exploring melatonin therapeutic potential in systemic lupus erythematosus

A recent review published in Current Molecular Pharmacology explores the therapeutic potential of melatonin in systemic lupus erythematosus (SLE), a complex autoimmune disease affecting multiple organs.

12 Dec 2025

Autoimmune attack on CASPR2 drives nerve hyperexcitability and involuntary muscle activity

A scientific review on autoimmune neurological diseases reveals what occurs in our body when the immune system, by mistake, produces antibodies that target a protein essential for the normal functioning of nerves.

12 Dec 2025

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Learn how digital connectivity and the PathoVerse are improving pathology workflows and accelerating access to expert diagnostics.

From PathPresenter 12 Dec 2025

Massive genetics study shows what truly separates and unites 14 psychiatric disorders

This large-scale genomic analysis of 14 psychiatric disorders shows that most heritable risk is shared across five broad genetic factors, with only limited disorder-specific variation. The study maps where risks converge or diverge biologically, revealing distinct cell type signatures and developmental pathways that may guide future diagnostic and therapeutic frameworks.

12 Dec 2025

Internet gaming disorder affects one in ten boys

Do your kids play a lot of computer games? Some may end up gaming a little too obsessively. Researchers have identified the most important warning signs.

11 Dec 2025

Preoperative MRI offers no survival benefit for early-stage breast cancer patients

Patients with stage 1 or 2, hormone receptor (HR)-negative breast cancer had similar five-year rates of locoregional recurrence whether or not they underwent preoperative breast magnetic resonance imaging (MRI) in addition to diagnostic mammography to determine the extent of their cancer, according to results from the phase III Alliance A011104/ACRIN 6694 clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

11 Dec 2025

More AI explanations can reduce accuracy in cancer diagnosis

In recent years AI has emerged as a powerful tool for analyzing medical images. Thanks to advances in computing and large medical datasets from which AI can learn, it has proven to be a valuable aid in reading and analyzing patterns in X-rays, MRIs and CT scans, enabling doctors to make better and faster decisions, particularly in the treatment and diagnosis of life-threatening diseases like cancer.

11 Dec 2025

Study reveals shared genetic roots across multiple psychiatric disorders

Distinct psychiatric disorders have more in common biologically than previously believed, according to the largest and most detailed analysis to date of how genes influence mental illness.

11 Dec 2025

New molecular ruler enables precise measurement of toxic Tau fibrils in fluid samples

Researchers have developed a new tool, FibrilPaint combined with the FibrilRuler test, that allows scientists to directly measure the length of toxic Tau amyloid fibrils in tiny fluid samples, from the earliest aggregation stages to mature fibrils and even at very low concentrations.

11 Dec 2025

New CDC grant supports expansion of colorectal cancer screening across rural Pennsylvania

Increasing colorectal cancer screening rates among communities with the greatest need is the goal of a five-year, $4.2 million grant from the Centers for Disease Control and Prevention (CDC) to Penn State College of Medicine.

11 Dec 2025

AI-based tool may help personalize the treatment of patients with reduced coronary blood flow

Reduced coronary blood flow, measured with an artificial intelligence-based imaging tool, predicted future cardiovascular events in patients with suspected stable coronary artery disease.

11 Dec 2025

Researchers identify a distinct immuno-inflammatory biomarker across major psychiatric disorders

Individuals with psychiatric disorders exhibiting seemingly similar symptoms often respond very differently to the same treatment, suggesting that distinct biological processes are at work beneath the surface of similar clinical presentations.

11 Dec 2025

Shared genetic roots of 14 psychiatric disorders revealed

Researchers from the Psychiatric Genomics Consortium (PGC) report that most genetic influences on mental illness are shared across diagnostic categories, revealing a more interconnected biological landscape than traditional classifications suggest.

11 Dec 2025

New AAN guideline offers treatment strategies for functional seizures

To help neurologists, mental health clinicians and other clinicians determine the best ways to help people manage functional seizures, the American Academy of Neurology has issued a new guideline, published on December 10, 2025, in Neurology, the medical journal of the American Academy of Neurology.

10 Dec 2025

Screen time and ADHD: why social media stands out from gaming and TV

Over four years in a large US cohort, greater social media use was associated with small but consistent increases in inattention symptoms in children, while video games and television were not. Genetic risk for ADHD did not modify this inattention association, and analyses supported a directional link from social media use to later attention difficulties.

10 Dec 2025

Many arrested individuals in London may have undiagnosed ADHD or autism

Offering screening for neurodivergence to people detained by the police could help ensure access to appropriate support and fairer treatment in the criminal justice system, say Cambridge researchers, after a study suggests that one in two individuals arrested and detained in London may have undiagnosed attention-deficit/hyperactivity disorder (ADHD) and one in 20 may have undiagnosed autism.

10 Dec 2025

Early warning for diabetes: AI model identifies prediabetes risk with high accuracy

A Scientific Reports study developed a pattern neural network that integrates total antioxidant status with clinical and metabolic markers to predict prediabetes in Indian adults. The model achieved very high accuracy and highlighted oxidative stress and waist circumference as key predictors, supporting earlier detection before progression to type 2 diabetes.

10 Dec 2025

AI model improves recurrence risk stratification in HR-positive, HER2-negative breast cancer

An artificial intelligence (AI) model created by integrating clinical, molecular, and histopathological data significantly improved recurrence risk stratification in hormone receptor (HR)-positive, HER2-negative breast cancer, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

10 Dec 2025

Study offers a unified biological model to explain the causes of autism

A new University of California San Diego School of Medicine study offers a unified biological model to explain how genetic predispositions and environmental exposures converge to cause autism spectrum disorder (ASD).

10 Dec 2025

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Diagnostic News and Research

Metabolic syndrome affects nearly four in ten US adults as rates climb in older and Black populations

Exploring melatonin therapeutic potential in systemic lupus erythematosus

Autoimmune attack on CASPR2 drives nerve hyperexcitability and involuntary muscle activity

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Massive genetics study shows what truly separates and unites 14 psychiatric disorders

Internet gaming disorder affects one in ten boys

Preoperative MRI offers no survival benefit for early-stage breast cancer patients

More AI explanations can reduce accuracy in cancer diagnosis

Study reveals shared genetic roots across multiple psychiatric disorders

New molecular ruler enables precise measurement of toxic Tau fibrils in fluid samples

New CDC grant supports expansion of colorectal cancer screening across rural Pennsylvania

AI-based tool may help personalize the treatment of patients with reduced coronary blood flow

Researchers identify a distinct immuno-inflammatory biomarker across major psychiatric disorders

Shared genetic roots of 14 psychiatric disorders revealed

New AAN guideline offers treatment strategies for functional seizures

Screen time and ADHD: why social media stands out from gaming and TV

Many arrested individuals in London may have undiagnosed ADHD or autism

Early warning for diabetes: AI model identifies prediabetes risk with high accuracy

AI model improves recurrence risk stratification in HR-positive, HER2-negative breast cancer

Study offers a unified biological model to explain the causes of autism

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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