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Two genetic variants linked to breast cancer discovered in black South African women

Genetic factors contribute to some 30% of breast cancer cases in SA, necessitating investment in genomic research in African contexts.

15 May 2025

Air travel disrupts DNA repair in flight crew, raising cancer concerns

Researchers found that flight attendants show reduced DNA repair capacity and immune changes after air travel, which may help explain their higher cancer risk.

14 May 2025

Researchers unlock new paths toward treating stress-related psychiatric disorders

In a comprehensive Genomic Psychiatry review article published today, researchers from the University of Rochester Medical Center have synthesized decades of research on stress hormone systems in primate brains, potentially unlocking new paths toward treating stress-related psychiatric disorders.

13 May 2025

New brain network discovery could revolutionize depression diagnosis

In a comprehensive Genomic Press Commentary published today, researchers have identified what could be the first reliable biomarker for depression risk, potentially transforming how this devastating condition is identified and treated.

13 May 2025

‘Cell line atlas’ can help better understand biliary tract cancer biology

Advanced biliary tract cancer (BTC) includes cholangiocarcinoma, gallbladder carcinoma, and ampullary carcinoma. BTC is a rare and aggressive group of cancers, carrying one of the worst prognoses in all of oncology.

12 May 2025

Researchers uncover how Entamoeba histolytica evades the immune system

The single-celled parasite Entamoeba histolytica infects 50 million people each year, killing nearly 70,000. Usually, this wily, shape-shifting amoeba causes nothing worse than diarrhea.

12 May 2025

Newly identified gene mutation causes severe form of Fanconi anemia

Fanconi anemia is an aggressive, life-threatening disorder. Most individuals living with this rare genetic condition, characterized by bone marrow failure and cancer predisposition, survive into adulthood only with bone marrow transplantation and regular cancer screening.

11 May 2025

Machine learning model guides smarter gene selection in newborn screening

More than a decade ago, researchers launched the BabySeq Project, a pilot program to return newborn genomic sequencing results to parents and measure the effects on newborn care.

10 May 2025

Why your baby’s first steps may be written in their DNA

Researchers identified 11 genetic loci linked to the age at which infants start walking, revealing that this milestone is influenced by thousands of common genetic variants. These genetic factors also correlate with brain development, cognitive traits, and neurodevelopmental conditions like ADHD.

8 May 2025

Wildlife trade, not bats, likely moved the ancestors of SARS-CoV-2 to humans

New genetic analyses reveal that the bat virus ancestors of SARS-CoV-1 and SARS-CoV-2 likely circulated in Western China or Northern Laos just years before human outbreaks. Their rapid appearance thousands of kilometers away suggests wildlife trade, not bat migration, was the likely transmission path.

8 May 2025

Scientists build world's most accessible gut bacteria collection to unlock health and disease clues

Researchers have developed the Human Intestinal Bacteria Collection (HiBC), comprising 340 gut bacterial strains from 198 species, including 29 newly described taxa, made publicly available for functional microbiome research.

7 May 2025

Research reveals how psychedelics reshape communication between the brain and immune system

In a compelling Genomic Press interview published today, rising scientific star Dr. Michael Wheeler unveils revolutionary findings about how psychedelics reshape communication between the brain and immune system, potentially transforming treatments for psychiatric disorders and inflammatory diseases alike.

6 May 2025

MED13L Foundation funds groundbreaking study at Boston Children's Hospital

The MED13L Foundation today announced a nearly $250,000 grant to help launch an innovative natural history study at Boston Children's Hospital's Rosamund Stone Zander Translational Neuroscience Center (RSZ TNC).

5 May 2025

Gene-edited immune cells show promise against advanced GI cancers

Researchers at the University of Minnesota have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers.

3 May 2025

Clusterin identified as key marker for aging in blood stem cells

In recent years, there has been a growing trend of an aging patient population and an increasing prevalence of age-associated diseases, underscoring the need for advancing research into the biological mechanisms of aging.

30 Apr 2025

Tailored treatment guided by dual biopsy approach may improve outcomes for patients with advanced cancers

Patients with advanced solid tumors experienced significantly improved survival outcomes when receiving a tailored therapy based on the detection of the same genomic alteration in both tissue and liquid biopsies compared with both standard-of-care treatment and tailored therapy that was based on either biopsy on its own, according to results from the phase II, multicenter ROME trial presented at the American Association for Cancer Research (AACR) Annual Meeting 2025, held April 25-30.

29 Apr 2025

Researchers uncover how substance use accelerates brain aging

In a comprehensive Genomic Press Interview, researchers from UTHealth Houston have uncovered crucial evidence that substance use disorders (SUDs) accelerate biological aging in the brain through distinct molecular mechanisms.

29 Apr 2025

PET scans reveal early signs of Parkinson’s and Lewy body disorders

In a comprehensive Genomic Press perspective article published today, researchers from Fudan University and Shanghai University of Traditional Chinese Medicine have highlighted remarkable advances in the development of positron emission tomography (PET) tracers capable of visualizing α-synuclein aggregates in the brains of patients with Parkinson's disease and related disorders.

29 Apr 2025

Global Virus Network urges action to prevent H5N1 pandemic

Today, the Global Virus Network (GVN), representing eminent human and animal virologists from 80+ Centers of Excellence and Affiliates in 40+ countries, published a comprehensive analysis and call-to-action in The Lancet Regional Health-Americas on the North American avian influenza virus, or H5N1, outbreak. The GVN calls on world governments to address the threat of H5N1 avian influenza by enhancing surveillance, implementing biosecurity measures, and preparing for potential human-to-human transmission.

29 Apr 2025

Immunotherapy replaces surgery for early-stage dMMR cancers in landmark study

Neoadjuvant PD-1 blockade with dostarlimab achieved high rates of organ preservation in patients with early-stage mismatch repair-deficient (dMMR) solid tumors across multiple types. Most patients avoided surgery with durable disease control, reshaping potential cancer treatment pathways.

28 Apr 2025