Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a growing global health concern, affecting millions worldwide. This complex liver disorder ranges from simple steatosis to more severe forms, including metabolic dysfunction-associated steatohepatitis (MASH), which may progress to fibrosis, cirrhosis, and even liver cancer.

11 Mar 2025

GLP-1 drugs may cut risk of leukemia and lymphoma in type 2 diabetes patients

Researchers found that GLP-1 receptor agonists (GLP-1RAs) significantly reduce the risk of several blood cancers in type 2 diabetes patients, especially compared to insulin. The study also highlights GLP-1RAs’ potential as a cancer-protective treatment, independent of glucose control.

9 Mar 2025

Understanding the role of LSD1 in cellular processes and disease

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes and its implications for human diseases.

8 Mar 2025

Research links kidney dysfunction to muscle weakness in myotonic dystrophy type 1

Thurman M. Wheeler, MD, of the Department of Neurology at Massachusetts General Hospital, is the senior author of a paper published in Nature Communications, "Analysis of human urinary extracellular vesicles reveals disordered renal metabolism in myotonic dystrophy type 1."

8 Mar 2025

High-fat diet could cause memory problems in older adults after just a few days

Just a few days of eating a diet high in saturated fat could be enough to cause memory problems and related brain inflammation in older adults, a new study in rats suggests.

6 Mar 2025

New research links early-life microbes to long-term metabolic health

The microbiome shapes development of insulin-producing cells in infancy, leading to long-term changes in metabolism and diabetes risk, new research in mice has found.

6 Mar 2025

Snoring regularly? Your diabetes risk jumps if you had gestational diabetes

Short sleep duration and frequent snoring significantly raise the risk of type 2 diabetes in women with prior gestational diabetes. Regular snoring is also linked to poorer glucose metabolism biomarkers.

6 Mar 2025

Eating ultra-processed foods harms your gut—here’s how inflammation takes hold

Ultra-processed foods disrupt gut microbiome balance, causing inflammation, reduced microbial diversity, and increased gut permeability. This microbiome imbalance contributes to chronic diseases including diabetes, IBD, cancer, and neurological disorders.

6 Mar 2025

Diabetes changes the biology of breast cancer, study shows

More than 120 million Americans suffer from diabetes or pre-diabetes. Triple-negative breast cancer (TNBC) is the most aggressive form of breast cancer, and TNBC patients with obesity-driven diabetes often have worse outcomes.

6 Mar 2025

Study finds Pacific children struggling with micronutrient intake and obesity

Children ages two to eight years across 11 Pacific jurisdictions (Alaska, American Samoa, Commonwealth of the Northern Mariana Islands, Federated States of Micronesia, Guam, Hawai'i, Marshall Islands, and Palau) are not meeting daily recommended intakes for key micronutrients, either consuming too much or too little.

6 Mar 2025

Naturally occurring molecule suppresses appetite and promotes weight loss

A naturally occurring molecule identified by Stanford Medicine researchers appears similar to semaglutide - also known as Ozempic - in suppressing appetite and reducing body weight.

6 Mar 2025

Feeding strategies in preterm infants do not alter brain growth or cognition

Early nutrition in very preterm infants does not significantly impact brain growth or neurodevelopment when following standardized clinical guidelines, despite initial unadjusted associations.

5 Mar 2025

Carbs aren’t the hunger culprit: New research overturns belief that glycemic index drives overeating

A Cell Metabolism study finds that while high-GI meals spike insulin and glucose, they don’t increase hunger or consistently drive overeating, challenging the carbohydrate-insulin model’s central claims about obesity.

5 Mar 2025

Study shows benefits of GLP-1 drugs for kidney transplant recipients with type 2 diabetes

Kidney transplant recipients with type 2 diabetes treated with a new class of anti-obesity drugs were less likely to experience organ failure and survived longer, a new study shows.

5 Mar 2025

Daily mango consumption may improve insulin sensitivity in overweight or obese adults

New research has uncovered a potential gamechanger for improving cardiometabolic health: fresh mangos.

5 Mar 2025

New insights into miRNA roles in diabetic cardiomyopathy immune regulation

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Diabetic cardiomyopathy (DCM), an independent diabetes complication, is characterized by abnormalities in myocardial structure, function, and metabolism, including diminished myocardial contractility, myocardial hypertrophy, and fibrosis.

5 Mar 2025

Researchers discover neural mechanism behind leptin resistance and a way to reverse it

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category.

4 Mar 2025

Novel strategy targets beta cell dysfunction in type 2 diabetes

Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity-a harmful condition linked to the progression of type 2 diabetes (T2D).

4 Mar 2025

How accurate are continuous glucose monitors? A study puts them to the test

Continuous glucose monitors consistently overestimate fasting and post-meal blood glucose levels compared to capillary blood glucose measurements.

4 Mar 2025

Breakthrough research uncovers way to maintain metabolism during calorie restriction

Many people who have tried to lose weight by cutting calories are familiar with this frustrating reality: at some point, the body stops shedding pounds.

3 Mar 2025