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Providing quick & efficient CRO services with Sino Biological

In this interview, News-Medical talks to Dr. Lin Yutao, head of project management at Sino Biological, about the work she does and how Sino provides quick and efficient recombinant CRO services.

From Sino Biological Inc. 15 Dec 2021

Assay for the identification of SARS-CoV-2 Spike reactive T and B cells

An interesting new paper presents a new assay for B and T lymphocytes in individuals infected with SARS-CoV-2.

14 Dec 2021

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

A group of researchers from various institutions developed a nucleoside-modified mRNA vaccine that encodes the SARS-CoV-2 N protein (mRNA-N) and is formulated in lipid nanoparticles for this investigation (LNP).

14 Dec 2021

Bioinformatics pipeline can be used to quickly identify SARS-CoV-2 therapeutics

In a new study, researchers developed a bioinformatics pipeline that uses RNA sequencing data to identify altered genes and signaling pathways affected by viral infection.

13 Dec 2021

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses like human immunodeficiency virus (HIV).

9 Dec 2021

Yokogawa Develops Single Cellome System SS2000 for Subcellular Sampling

A single-cell analysis solution that revolutionizes efficiency in drug discovery research by automating the collection of specific cells and intracellular components.

From Yokogawa Life Science 9 Dec 2021

Study identifies ORF8 protein as a key COVID-19 causing factor

New study suggests that the SARS-CoV-2 ORF8 protein is the underlying cause behind severe COVID-19 infection.

8 Dec 2021

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

In a recent study conducted at Yale University, USA, scientists have investigated the immunogenicity of mRNA-based coronavirus disease 2019 (COVID-19) vaccine candidates encoding the spike proteins of different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. The findings reveal that the vaccines induce robust immune responses against SARS-CoV-2 variants. The study is currently available on the bioRxiv* preprint server.

6 Dec 2021

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

A new study supports the hypothesis that heterologous vaccination can provide an increased immune response against virus infection, supporting several other studies that have indicated similar events.

5 Dec 2021

In-depth analysis of SARS-CoV-2 specific T cells in unexposed individuals

A new study aimed to analyze SARS-CoV-2 specific T-cells in unexposed individuals.

2 Dec 2021

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Researchers employ a structure-guided approach for the development of a series of ACE2-Fc variants using human IgG1 or IgG3 backbone.

1 Dec 2021

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

In a recent study, published on the bioRxiv* preprint server, researchers identified human LRRC15 as an inhibitory receptor for SARS-CoV-2 entry, which directly binds to the receptor-binding domain (RBD) of the spike protein with a moderate affinity and inhibits spike-mediated entry.

29 Nov 2021

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound known as interferon, allowing for the mitigation of coronavirus disease (COVID-19) severity. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

28 Nov 2021

Intracellular News and Research

Providing quick & efficient CRO services with Sino Biological

Assay for the identification of SARS-CoV-2 Spike reactive T and B cells

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

Bioinformatics pipeline can be used to quickly identify SARS-CoV-2 therapeutics

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Yokogawa Develops Single Cellome System SS2000 for Subcellular Sampling

Study identifies ORF8 protein as a key COVID-19 causing factor

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

In-depth analysis of SARS-CoV-2 specific T cells in unexposed individuals

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

Efficacy and safety of an RBD-based recombinant protein COVID-19 vaccine

Using metal nanoparticles to fight SARS-CoV-2

Mapping cell structure by fusing protein images and interactions

Mtb's exotoxin secretion and trafficking mechanism revealed

Researchers analyze live bacteria from cystic lesions that are precursors to pancreatic cancer

Experimental compound reduces diabetic complications in mice

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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