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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Protein synthesis regulatory factor vital for long-term memory formation

The research group of Associate Professor Nobuyuki Shiina of the National Institute for Basic Biology have revealed that the function of RNG105 (aka Caprin1) is essential for the formation of long-term memory.

22 Nov 2017

Oncologists find new biomarker for breast cancer having poor prognosis

With the support of the FWF, an oncologist found a biomarker for breast cancer having a poor prognosis and developed two viable methods to detect it in tissue samples.

22 Nov 2017

Analysis of aged brains reveals new details about Alzheimer's disease and dementia

In a comprehensive analysis of samples from 107 aged human brains, researchers at the Allen Institute for Brain Science, UW Medicine and Kaiser Permanente Washington Health Research Institute have discovered details that will help researchers better understand the biological bases for Alzheimer's disease and dementia in older populations.

21 Nov 2017

High-fat diet during lactation alters RNA activity in breast milk, research suggests

New research suggests that following a high-fat diet during lactation - regardless of diet during pregnancy - alters RNA activity in breast milk. The changes in genetic material may increase the risk of metabolic disorders such as type 2 diabetes in offspring. The article is published ahead of print in Physiological Genomics.

21 Nov 2017

Scientists develop novel technology that uses CRISPR to map genetic mutations

A team of scientists led by Virginia Commonwealth University physicist Jason Reed, Ph.D., have developed new nanomapping technology that could transform the way disease-causing genetic mutations are diagnosed and discovered.

21 Nov 2017

Researchers identify previously unknown breast cell types

A joint effort by breast cancer researchers and bioinformaticians has provided new insights into the molecular changes that drive breast development.

21 Nov 2017

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

Serious liver and heart problems can affect children with Alagille Syndrome early in life. While there is as yet no cure, researchers at Karolinska Institutet in Sweden have discovered that the liver disease part of the syndrome is caused by specific malformations of the bile ducts.

21 Nov 2017

New technique may reveal clues about role of centromeres in Down syndrome, other birth defects

Some scientists call it the "final frontier" of our DNA -- even though it lies at the center of every X-shaped chromosome in nearly every one of our cells.

20 Nov 2017

Small molecules in saliva may offer clues to diagnose and predict duration of concussions

Diagnosing a concussion can sometimes be a guessing game, but clues taken from small molecules in saliva may be able to help diagnose and predict the duration of concussions in children, according to researchers at Penn State College of Medicine.

20 Nov 2017

CRISPR shows potential to reduce diseases spread by mosquitoes

Research at the University of California, Riverside, have shown that it is possible for transgenic mosquitos to stably express the Cas9 enzyme in their germline. Cas9 addition will allow the utilization of the CRISPR gene editing tool to carry out efficient and highly targeted changes to the DNA of the mosquitoes.

16 Nov 2017

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem cells because they can differentiate to all those different cell fates.

15 Nov 2017

Researchers visualize mechanism of CRISPR-Cas9 genetic-engineering technique

Researchers at Kanazawa University and the University of Tokyo report in Nature Communications the visualization of the dynamics of ‘molecular scissors’ — the main mechanism of the CRISPR-Cas9 genetic-engineering technique.

15 Nov 2017

Nanoparticles carrying CRISPR gene editing tools for genetic modifications

Researchers from MIT have now developed nanoparticles that could carry CRISPR genetic editing systems deep within the cells and perform their functions on the DNA. The paper was published in the November issue of Nature Biotechnology.

14 Nov 2017

Synthetic double-stranded RNA may have potential for use as vaccine to prevent liver cancer

Primary liver cancer is now the second leading cause of cancer-related death worldwide, and its incidences and mortality are increasing rapidly in the United Stated. In late stages of the malignancy, there are no effective treatments or drugs.

14 Nov 2017

UCR researchers develop transgenic mosquitoes to help reduce spread of infectious diseases

Researchers at the University of California, Riverside have developed transgenic mosquitoes that stably express the Cas9 enzyme in their germline. The addition of Cas9 will enable the use of the CRISPR gene editing tool to make efficient, targeted changes to the mosquitoes' DNA.

14 Nov 2017

Scientists develop novel mouse model to capture pathology of sporadic ALS and FTD

Neurodegenerative diseases are incurable and debilitating conditions that result in progressive degeneration and death of nerve cells, which leads to problems with movement or mental functioning. Examples include Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

13 Nov 2017

RNA News and Research

Further Reading

Protein synthesis regulatory factor vital for long-term memory formation

Oncologists find new biomarker for breast cancer having poor prognosis

Analysis of aged brains reveals new details about Alzheimer's disease and dementia

High-fat diet during lactation alters RNA activity in breast milk, research suggests

Scientists develop novel technology that uses CRISPR to map genetic mutations

Researchers identify previously unknown breast cell types

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

New technique may reveal clues about role of centromeres in Down syndrome, other birth defects

Small molecules in saliva may offer clues to diagnose and predict duration of concussions

CRISPR shows potential to reduce diseases spread by mosquitoes

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

Researchers visualize mechanism of CRISPR-Cas9 genetic-engineering technique

Nanoparticles carrying CRISPR gene editing tools for genetic modifications

Synthetic double-stranded RNA may have potential for use as vaccine to prevent liver cancer

UCR researchers develop transgenic mosquitoes to help reduce spread of infectious diseases

Scientists develop novel mouse model to capture pathology of sporadic ALS and FTD

Study finds potential chemical compound that initiated life on Earth

New discovery in beta-cell pathway shows potential to improve effectiveness of diabetes drugs

Roundworms may provide new clues to nicotine dependence

Texas Biomedical Research Institute tests promising new treatment for HBV infection

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