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Study reports promising new monoclonal antibody against SARS-CoV-2’s spike protein

An encouraging new study describes a promising new therapeutic antibody that shows potent neutralizing activity against SARS-CoV-2, the causative agent of COVID-19.

15 Jan 2021

Researchers discover unexpected role for the clock gene in prostate cancer progression

Our biological or circadian clock synchronizes all our bodily processes to the natural rhythms of light and dark. It's no wonder then that disrupting the clock can wreak havoc on our body.

15 Jan 2021

5 reasons to wear a mask even after you’re vaccinated

As an emergency physician, Dr. Eugenia South was in the first group of people to receive a covid vaccine. She received her second dose last week — even before President-elect Joe Biden.

15 Jan 2021

Researchers to study potential treatment for limb dysfunction in patients with chronic spinal cord injury

Ghaith Androwis, PhD, and Steven Kirshblum, MD, received a grant from BrainQ Technologies to study a potential treatment for arm and hand dysfunction in individuals with chronic spinal cord injury.

15 Jan 2021

MVA SARS-CoV-2 vaccine candidate shows strong immunogenicity in preclinical trials

A new study reports the preclinical testing of a recombinant MVA (rMVA) candidate vaccine against SARS-CoV-2, the agent that is causing the current COVID-19 pandemic.

14 Jan 2021

Could intranasal SARS-CoV-2 vaccines be a practical alternative to intramuscular shots?

The unchecked advance of COVID-19 has made it a top public health priority to produce a vaccine capable of inducing a safe and powerful protective response against its causative pathogen: SARS-CoV-2. An encouraging new study shows the immunogenicity, safety, and protective efficacy, of a Newcastle disease virus (NDV)-based intranasal vector vaccine in animal studies.

14 Jan 2021

Moderna to develop three new mRNA-based vaccines against HIV, influenza, and the Nipah virus

Morderna has announced plans to develop a range of new mRNA-based vaccines against other viruses, including the influenza virus, human immunodeficiency virus (HIV), and the Nipah virus.

13 Jan 2021

New N501 SARS-CoV-2 mutation may have been circulating in Italy since August 2020

A recent study shows that mutated SARS-CoV-2 strains with a substitution at position 501 might have circulated unnoticed even before the end of September 2020, when the rapid emergence of B.1.1.7 lineage (carrying the N501Y mutation) was initially reported.

13 Jan 2021

Researchers produce lightweight grab-poles with anti-microbial property for public transport

Since the beginning of the Covid-19 pandemic many people have been, or may feel, hesitant about taking public transport, due to the perceived risk of picking up germs from areas such as the grab-poles on trains, buses and trams, which are the principal point of contact.

13 Jan 2021

Could fenofibrate be an effective antiviral against SARS-CoV-2?

The resurgence of COVID-19 pandemic, caused by the SARS-CoV-2, has led to renewed efforts to find effective antivirals, both newly developed or repurposed drugs. A study reports the efficacy of the cholesterol-reducing drug fenofibrate in reducing infection rates of SARS-CoV-2 in cultured cells.

13 Jan 2021

Study shows how cardiosphere-derived cells replenish damaged tissues in dilated cardiomyopathy

Dilated cardiomyopathy (DCM) is a condition caused by the weakening of the heart muscle, affecting the ventricles (chambers in the heart that push blood around the body as it contracts).

13 Jan 2021

Effect of mutations in the South African SARS-CoV-2 variant on transmission and neutralization

One such strain is the South African 501.V2 and UK B1.1.7 strains, which have been isolated from many countries and seem to spread faster than the ancestral strain. A preprint that recently appeared on the bioRxiv server reports the computational structure of this strain and the possible effect of the mutations on infectivity and neutralization.

12 Jan 2021

Daily circadian cycles may impact our ability to fight disease

An analysis of an exhaustive dataset on cells essential to the mammalian immune system shows that our ability to fight disease may rely more heavily on daily circadian cycles than previously assumed.

12 Jan 2021

Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Reprogramming the rich connective tissue microenvironment of a liver cancer known as intrahepatic cholangiocarcinoma (ICC) inhibits its progression and resistance to standard chemotherapy in animal models, researchers from Massachusetts General Hospital have found.

12 Jan 2021

Researchers study the effectiveness of FEND product to improve airway hygiene

In a paper published in Molecular Frontiers Journal, researchers from Cambridge, Massachusetts and Bangalore, India study the effectiveness of FEND product to significantly improve airway hygiene by reducing and suppressing respiratory droplets potentially containing airborne pathogens and other contaminants.

12 Jan 2021

Will the Pfizer–BioNTech vaccine be effective against the new N501Y SARS-CoV-2 variant?

Researchers from Pfizer and the University of Texas, USA, have presented evidence showing that people in a previously reported trial of the mRNA-based COVID-19 vaccine, BNT162b2 – commonly known as the Pfizer-BioNTech COVID-19 vaccine – had equivalent neutralizing titers to the N501 and Y501 viruses.

12 Jan 2021

Study investigates effect of anti-CD45 RIT lymphodepletion on immune cell types

Oncotarget recently published "Targeted lymphodepletion with a CD45-directed antibody radioconjugate as a novel conditioning regimen prior to adoptive cell therapy" which reported that Chimeric antigen receptor T cell therapies, and adoptive cell therapy in general, represent one of the most promising anti-cancer strategies.

12 Jan 2021

Insulin nanoparticles may become an alternative to insulin injections for diabetic patients

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed insulin nanoparticles that may one day become the basis for an oral medicine, and an alternative to insulin injections for diabetic patients.

12 Jan 2021

Study supports continuing phase 3 trials of Ad26.COV2.S SARS-CoV-2 vaccine

An international team of researchers has provided further evidence to confirm the immunogenicity and efficacy of a recombinant adenovirus vaccine currently being tested in phase 3 trials for its ability to protect against infection with severe acute respiratory coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

11 Jan 2021

Extract of medicinal plant Artemisia annua interferes with replication of SARS-CoV-2 in vitro

Researchers in the United States have shown that extracts of an aromatic herb called Artemisia annua inhibit the replication of severe acute respiratory coronavirus (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

11 Jan 2021

Efficacy News and Research

Study reports promising new monoclonal antibody against SARS-CoV-2’s spike protein

Researchers discover unexpected role for the clock gene in prostate cancer progression

5 reasons to wear a mask even after you’re vaccinated

Researchers to study potential treatment for limb dysfunction in patients with chronic spinal cord injury

MVA SARS-CoV-2 vaccine candidate shows strong immunogenicity in preclinical trials

Could intranasal SARS-CoV-2 vaccines be a practical alternative to intramuscular shots?

Moderna to develop three new mRNA-based vaccines against HIV, influenza, and the Nipah virus

New N501 SARS-CoV-2 mutation may have been circulating in Italy since August 2020

Researchers produce lightweight grab-poles with anti-microbial property for public transport

Could fenofibrate be an effective antiviral against SARS-CoV-2?

Study shows how cardiosphere-derived cells replenish damaged tissues in dilated cardiomyopathy

Effect of mutations in the South African SARS-CoV-2 variant on transmission and neutralization

Daily circadian cycles may impact our ability to fight disease

Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Researchers study the effectiveness of FEND product to improve airway hygiene

Will the Pfizer–BioNTech vaccine be effective against the new N501Y SARS-CoV-2 variant?

Study investigates effect of anti-CD45 RIT lymphodepletion on immune cell types

Insulin nanoparticles may become an alternative to insulin injections for diabetic patients

Study supports continuing phase 3 trials of Ad26.COV2.S SARS-CoV-2 vaccine

Extract of medicinal plant Artemisia annua interferes with replication of SARS-CoV-2 in vitro

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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