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COVID-19 pandemic and nanotechnology

Writing in the International Journal of Nanomedicine, Professor Dongki Yang, from the Department of Physiology, Gachon University, South Korea, has reviewed the available knowledge on the coronaviruses, current approaches to tackle the newly emerged SARS-CoV-2 infection, and the innovative application of nanotechnology in the COVID-19 pandemic.

8 Feb 2021

Discovery of ‘Achilles heel’ in gut bacteria may lead to targeted therapies for Crohn’s disease

The discovery of an "Achilles heel" in a type of gut bacteria that causes intestinal inflammation in patients with Crohn's disease may lead to more targeted therapies for the difficult to treat disease, according to Weill Cornell Medicine and NewYork-Presbyterian investigators.

6 Feb 2021

Novel immunotherapy approach to revert the main hallmarks of cat allergy

Researchers from the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) brought forward the potential of high doses of a specific adjuvant molecule, namely CpG oligonucleotide, in successfully modulating the immune system's allergic response to the main cat allergen Fel d 1, thereby inducing a tolerance-promoting reaction and reverting the main hallmarks of cat allergy.

5 Feb 2021

How does SARS-CoV-2 infect the pancreas?

To understand how SARS-CoV-2 infects the pancreas and investigate its effects, a team of researchers used the human iPSC (induced pluripotent stem cells)-derived pancreatic cultures and analyzed the post-infection cellular and molecular changes.

5 Feb 2021

Study uncovers link between T cell-mediated inflammation and cardiac dysfunction

Inflammation is supposed to help protect us - it's part of an immune response to fight off pathogens and clear infections. But patients with cardiac disease often have chronic inflammation that damages their hearts, even with no infection present.

5 Feb 2021

GLS1 inhibitor selectively eliminates senescent cells, ameliorates age-associated disorders

Senescent cells accumulate in organs during aging, promote tissue dysfunction, and cause numerous aging-related diseases like cancer. The cells arise through a process called "cellular senescence," a permanent cell cycle arrest resulting from multiple stresses.

5 Feb 2021

Zinc supplements can improve infertility issues during COVID-19 pandemic

Wayne State University School of Medicine researchers have reported that zinc supplements for men and women attempting to conceive either naturally or through assisted reproduction during the COVID-19 pandemic may prevent mitochondrial damage in young egg and sperm cells, as well as enhance immunity against the virus.

5 Feb 2021

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

A healthy person has a general balance of good and bad bacteria. But that balance is thrown off when someone gets sick.

5 Feb 2021

Study may lead to new therapeutic strategies to reduce allergic responses, inflammatory reactions

In order to fight pathogens, mast cells regulate inflammatory reactions of the immune system. Both mast cells and neutrophils are white blood cells and are critical for the body's immune defense.

5 Feb 2021

Research shows intestinal parasite infestations reduce COVID-19 severity

Now, new research out of Mekelle, Ethiopia, examines the role of parasitic infestation on the prognosis of COVID-19. The research paper, which appears on the preprint server medRxiv, shows that intestinal parasitosis is protective against severe COVID-19.

4 Feb 2021

Emory MVA COVID-19 vaccine proven safe and effective in mice and monkeys

Researchers at Yerkes National Primate Research Center, Emory University, have developed a COVID-19 vaccine that has proven safe and effective in mice and monkeys.

4 Feb 2021

ZyCoV-D SARS-CoV-2 DNA vaccine shows robust immunogenicity and protective efficacy in Rhesus macaquesys

A team of scientists from India has recently tested the efficacy and immunogenicity of two different concentrations of a plasmid DNA-based vaccine candidate ZyCoV-D. The findings reveal that the vaccine candidate administered via Needle Free Injection System (NFIS) can significantly induce the production of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein-specific IgG and neutralizing antibodies for a prolonged period.

4 Feb 2021

Novel biomarker may help identify which pancreatic cancer patients respond to CD40 agonists

Inflammation in the blood could serve as a new biomarker to help identify patients with advanced pancreatic cancer who won't respond to the immune-stimulating drugs known as CD40 agonists, suggests a new study from researchers in the Abramson Cancer Center of the University of Pennsylvania published in JCI Insight.

4 Feb 2021

Research shows how air pollution has a detrimental impact on cardiovascular health

Tiny particles of air pollution -- called fine particulate matter -- can have a range of effects on health, and exposure to high levels is a known risk factor for cardiovascular disease.

4 Feb 2021

Researchers call for trials of rapamycin to treat COVID-19

Researchers in the United States, China, and the UK have called for immediate large-scale clinical trials of an antibiotic called rapamycin as a prophylactic and treatment approach to coronavirus disease 2019 (COVID-19) in older individuals.

4 Feb 2021

Gut microbiome can modulate the immune response in liver cancer patients with NAFLD

The distinctive gut microbiome profile of a person with liver cancer linked to non-alcoholic fatty liver disease (NAFLD) could be the key to predicting someone's risk of developing the cancer, say researchers from the UNSW Microbiome Research Centre.

4 Feb 2021

REGENHU announces its participation in the FLAMIN-GO project aimed at developing "personalized" treatments against rheumatoid arthritis

REGENHU announced its participation in the FLAMIN-GO research project aimed at developing an organ-on-chip technology for clinical trials on Rheumatoid Arthritis.

From regenHU Ltd. 4 Feb 2021

Sulforaphane prolongs lifespan and healthspan of C. elegans through insulin/IGF-1 signaling

Aging-US published "Sulforaphane promotes C. elegans longevity and healthspan via DAF- 16/DAF-2 insulin/IGF-1 signaling" which reported that the broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its effect on healthspan and longevity are unclear.

4 Feb 2021

Novel quantum sensor offers a new route to early diagnosis, preventive treatment

Oxygen is essential for human life, but within the body, certain biological environmental conditions can transform oxygen into aggressively reactive molecules called reactive oxygen species (ROS), which can damage DNA, RNA, and proteins.

4 Feb 2021

Study shows how tissue damage promotes the earliest stages of pancreatic cancer

Like weeds sprouting from cracks in the pavement, cancer often forms in sites of tissue damage. That damage could be an infection, a physical wound, or some type of inflammation.

4 Feb 2021

Inflammation News and Research

COVID-19 pandemic and nanotechnology

Discovery of ‘Achilles heel’ in gut bacteria may lead to targeted therapies for Crohn’s disease

Novel immunotherapy approach to revert the main hallmarks of cat allergy

How does SARS-CoV-2 infect the pancreas?

Study uncovers link between T cell-mediated inflammation and cardiac dysfunction

GLS1 inhibitor selectively eliminates senescent cells, ameliorates age-associated disorders

Zinc supplements can improve infertility issues during COVID-19 pandemic

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

Study may lead to new therapeutic strategies to reduce allergic responses, inflammatory reactions

Research shows intestinal parasite infestations reduce COVID-19 severity

Emory MVA COVID-19 vaccine proven safe and effective in mice and monkeys

ZyCoV-D SARS-CoV-2 DNA vaccine shows robust immunogenicity and protective efficacy in Rhesus macaquesys

Novel biomarker may help identify which pancreatic cancer patients respond to CD40 agonists

Research shows how air pollution has a detrimental impact on cardiovascular health

Researchers call for trials of rapamycin to treat COVID-19

Gut microbiome can modulate the immune response in liver cancer patients with NAFLD

REGENHU announces its participation in the FLAMIN-GO project aimed at developing "personalized" treatments against rheumatoid arthritis

Sulforaphane prolongs lifespan and healthspan of C. elegans through insulin/IGF-1 signaling

Novel quantum sensor offers a new route to early diagnosis, preventive treatment

Study shows how tissue damage promotes the earliest stages of pancreatic cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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