Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Dapagliflozin plus calorie restriction boosts remission rates in adults with type 2 diabetes and obesity

Findings indicate that dapagliflozin and calorie restriction together improve weight loss and metabolic health, increasing the likelihood of diabetes remission.

24 Jan 2025

Study links circulating short-chain fatty acids to type 2 diabetes risk

Short-chain fatty acids (SCFAs) serve as key signaling molecules linking gut microbiota and host health. Microbially produced SCFAs in the colon are generally acknowledged for their beneficial effects on cardiometabolic health, including enhancing insulin secretion, reducing plasma cholesterol and glucose levels, and controlling energy intake through the modulation of enteroendocrine hormones.

24 Jan 2025

Lean red meat in balanced diet supports gut and heart health, study reveals

A recent study from Purdue University scientists reveals following a consistent dietary pattern that features lean red meat can contribute to gut microbiota balance and support cardiovascular health.

23 Jan 2025

Non-industrialized diet improves health and reduces disease risk

Researchers have found that a newly developed diet inspired by the eating habits of non-industrialised societies can significantly reduce the risk of a number of chronic diseases – and are to share recipes with the public.

23 Jan 2025

Dapagliflozin and calorie restriction show higher remission rates in type 2 diabetes

Adults with overweight or obesity and type 2 diabetes who are given the sodium glucose cotransporter 2 (SGLT-2) inhibitor drug dapagliflozin alongside moderate calorie restriction achieve much higher rates of remission compared with calorie restriction alone, finds a trial published by The BMJ today.

23 Jan 2025

Nearly one-third of Americans exposed to unregulated contaminants in drinking water

Researchers assess socioeconomic disparities in exposure to unregulated contaminants present in public water systems throughout the United States.

22 Jan 2025

How lifestyle-based interventions help manage PCOS

Studies indicate that lifestyle modifications can alleviate PCOS symptoms, improving insulin resistance and hormonal balance through diet and physical activity.

21 Jan 2025

TyG index linked to obesity measures can predict hypertension risk in US adults

A study found that the triglyceride-glucose (TyG) index, combined with obesity measures, significantly correlates with hypertension risk in American adults, offering potential for improved cardiovascular risk assessment.

20 Jan 2025

Retinal vascular features identified as potential predictors of stroke risk

Researchers identify how specific features of the retinal vasculature may help predict an individual’s risk of stroke.

20 Jan 2025

New probes offer insight into cholesterol's role in Alzheimer's disease

The search for answers to Alzheimer's disease and other neurodegenerative disorders remains one of the most pressing goals in brain research. Maciej J. Stawikowski, Ph.D., an assistant professor of chemistry and biochemistry at Florida Atlantic University's Charles E. Schmidt College of Science, believes the key may lie in understanding how cholesterol and other lipids move through cells and affect their communication.

17 Jan 2025

Environmental disparities found in drinking water contamination across the U.S.

Nearly a third of people in the U.S. have been exposed to unregulated contaminants in their drinking water that could impact their health, according to a new analysis by scientists at Silent Spring Institute.

16 Jan 2025

PIN1 protein found to be a significant driver of bladder cancer

Like all cancers, bladder cancer develops when abnormal cells start to multiply out of control. But what if we could put a lid on their growth?

15 Jan 2025

Retina vascular fingerprint offers non-invasive way to predict stroke risk

A vascular 'fingerprint' on the light sensitive tissue layer at the back of the eye-the retina-can predict a person's risk of stroke as accurately as traditional risk factors alone, but without the need for multiple invasive lab tests, finds research published online in the journal Heart.

13 Jan 2025

U.S. dementia cases expected to surge with aging population

A new study shows that the risk of developing dementia anytime after age 55 among Americans is 42%, more than double the risk reported by older studies.

13 Jan 2025

Boston Scientific announces agreement to acquire Bolt Medical, Inc.

Boston Scientific Corporation today announced it has entered into a definitive agreement to acquire Bolt Medical, Inc., the developer of an intravascular lithotripsy (IVL) advanced laser-based platform for the treatment of coronary and peripheral artery disease.

From Boston Scientific 13 Jan 2025

Research explores molecular dynamics of CAR T cells in cancer treatment

A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer.

10 Jan 2025

A large-scale tongue cancer organoid library for precision oncology

Oral cancer is an increasingly prevalent disease worldwide, with over 300,000 new cases diagnosed each year. Among oral cancers, tongue cancer (TC) is the most common type and often carries a poor prognosis. Surgery combined with chemoradiotherapy is one of the main lines of treatment for high-risk cases of TC.

9 Jan 2025

Addressing COPD and metabolic syndrome requires comprehensive research efforts

Additional research addressing the connection between chronic obstructive pulmonary disease (COPD) and metabolic syndrome is needed to improve holistic patient care, according to a new editorial.

9 Jan 2025

Gut microbes and the body work together to regulate fat metabolism

Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study by investigators from Weill Cornell Medicine and the Boyce Thompson Institute at Cornell University's Ithaca campus.

9 Jan 2025

Can green tea help prevent cognitive decline?

Higher green tea consumption significantly reduces cerebral white matter lesions in older adults, offering potential protective effects against cognitive decline.

8 Jan 2025