Nucleic Acid News and Research

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Research sheds light on sun-induced DNA damage and repair

It is a well known fact that the sun’s ultraviolet rays can damage the skin. Now, a new study sheds light on what happens after DNA damage occurs, and how the body initiates repair.

15 Jul 2019

Researchers synthesize artificial cells to detect histamine

Baking a cake from scratch is a task deemed difficult for many. Constructing an artificial cell-like system from scratch, well that's another story.

3 Jul 2019

Study solves mysteries of complex microRNA oncogenes

MicroRNAs are tiny molecules of nucleic acid that control gene expression, acting like a dimmer switch to tone down gene output at key positions in the network of information that governs a cell's function.

28 Jun 2019

Fecal miRNAs could provide clues to early inflammation found in chronic gut conditions

Small molecules found in fecal matter could provide clues to the early inflammation found in chronic gut conditions, such as intestinal bowel disease, and serve as new biomarkers for diagnosis, according to a study led by the Institute for Biomedical Sciences at Georgia State University.

28 Jun 2019

Using Light Scattering to Characterize Protein-Nucleic Acid Interactions

Harnessing the interactions between DNA, RNA, and proteins holds much promise for detecting biomarkers, diagnosing disease, and improving cancer-targeting therapeutics. Quantifying these interactions is essential for understanding and controlling their biomolecular mechanisms.

From Waters | Wyatt Technology 26 Jun 2019

New spectroscopic approach investigates difficult-to-observe protein structures

Combining research-oriented teaching and interdisciplinary collaboration pays off: Researchers at the University of Konstanz develop a novel spectroscopic approach to investigate hitherto difficult-to-observe protein structures.

19 Jun 2019

Researchers develop DNA nanorobots that target breast cancer cells

According to the Mayo Clinic, about 20% of breast cancers make abnormally high levels of a protein called human epidermal growth factor receptor 2 (HER2).

17 Jun 2019

Gonorrhoea may be transmitted via kissing

Researchers in Australia have discovered that gonorrhea, which is considered to be a sexually transmitted disease, may actually be spread by oral sex and even kissing.

10 May 2019

Early clinical trial of new treatment for severe dry eye disease shows promising results

Participants in a phase I/II clinical trial of a new enzyme-based treatment for severe dry eye disease experienced reduced signs of disease and discomfort, according to a paper in Translational Vision Science and Technology.

7 May 2019

RIT faculty-researcher develops microfluidic device for early detection of Ebola virus

A faculty-researcher at Rochester Institute of technology has developed a prototype micro device with bio-sensors that can detect the deadly Ebola virus. With this type of device, those infected can be treated earlier, and the early detection process can potentially decrease the spread of infections.

3 May 2019

UA College partners with Space Tango to develop an easy way to test astronauts' health in space

Researchers at the University of Arizona College of Medicine - Phoenix are partnering with Space Tango, a private aerospace company that designs, builds and operates facilities on the International Space Station, to develop an easy way to test astronauts' health in space.

26 Apr 2019

Bentham Science's new volume delves into specific avenues of applied NMR studies

Bentham Science's seventh volume of Applications of NMR Spectroscopy, published by Bentham Science Publishers covers NMR methods in proteomics and metabolomics, and nucleic acid biochemistry.

26 Apr 2019

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

In this interview Dr Kushol Gupta, Research Assistant Professor in the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania talks to News-Medical and Life Sciences about the importance of light scattering techniques for investigating structure and mechanism of action in his ongoing research into HIV integrase and the development of HIV therapeutics.

From Waters | Wyatt Technology 24 Apr 2019

Spotlight on ECCMID 2019: Detecting Disease & Managing Infections

This article covers some of the highlights of ECCMID 2019, with insights into some of the companies and products being featured at the event.

From ESCMID 15 Apr 2019

High Throughput Nucleic Acid Purification Simplified

Labs demand purity and flexibility for high throughput nucleic acid purification, while needing to complete difficult downstream analysis, for example NGS.

From Promega Corporation 9 Apr 2019

UTMB receives grant to combat highly-lethal hemorrhagic fever viruses

The University of Texas Medical Branch at Galveston, Profectus Biosciences, Vanderbilt University Medical Center, Mapp Biopharmaceutical and Genevant Sciences Corp. have been awarded up to $35 million to advance the development of rapid-acting vaccines and broad-spectrum treatments of the highly-lethal hemorrhagic fever viruses Ebola and Marburg.

9 Apr 2019

Synthetic antibody rapidly prevents Zika infection in mice and non-human primates

A DNA-encoded monoclonal antibody prevents Zika infection in mice and non-human primates, researchers report April 5 in the journal Molecular Therapy.

8 Apr 2019

Wyss Technology licensed by Sherlock Biosciences to create affordable molecular diagnostics

Harvard University has granted a worldwide exclusive license to Sherlock Biosciences, Inc. to develop and commercialize technology from the Wyss Institute for Biologically Inspired Engineering to create a highly sensitive, nucleic acid-based diagnostic platform that can rapidly deliver accurate and inexpensive results for a vast range of needs in virtually any setting.

22 Mar 2019

An Insider’s Guide to the chemagic™ Prime™ Junior Instrument

Masoud Toloue from PerkinElmer provides an overview of the chemagic Prime Junior Instrument and gives his inside tips for scientists working with nucleic acids.

From Revvity 14 Mar 2019

Liver tissue model can help investigate the effects of RNA interference

Novel therapies based on a process known as RNA interference hold great promise for treating a variety of diseases by blocking specific genes in a patient's cells. Many of the earliest RNAi treatments have focused on diseases of the liver, because RNA-carrying particles tend to accumulate in that organ.

6 Mar 2019