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AI predicts effective treatment for rare disease using existing medications

After combing through 4,000 existing medications, an artificial intelligence tool helped uncover one that saved the life of a patient with idiopathic multicentric Castleman's disease (iMCD).

5 Feb 2025

New medication-based approach reverses inguinal hernias in mice

By age 75, a noteworthy 50% of men develop an inguinal (groin) hernia - a bulge that results from soft tissue pushing through a weak spot in the abdominal muscles.

5 Feb 2025

Breakthrough personalized vaccine shows promising results in kidney cancer trial

Dana-Farber Cancer Institute researchers report that all nine patients in a clinical trial being treated for stage III or IV clear cell renal cell carcinoma (a form of kidney cancer), generated a successful anti-cancer immune response after initiation of a personalized cancer vaccine.

5 Feb 2025

Neurostimulation improves movement in adults with spinal muscle atrophy

A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal muscle atrophy (SMA), an inherited neuromuscular disease.

5 Feb 2025

Juice cleanse may harm gut and oral health

Think your juice cleanse is making you healthier? A new Northwestern University study suggests it might be doing the opposite.

5 Feb 2025

Study reveals how healthy stem cells transform into cancer cells

Nearly 60,000 people are diagnosed with oral cancer in the U.S. every year, according to the American Cancer Society, and the rate of new cases continues to rise.

5 Feb 2025

Innovative method sheds light on the proteins behind gut health

A new Weizmann Institute study identified all of the proteins in a stool sample – those from the microbiome, the human body and food – revealing the hidden secrets of the intestines and their impact on human disease

5 Feb 2025

Rising cannabis use disorder cases contribute to growing schizophrenia diagnoses

The proportion of new cases of schizophrenia associated with a cannabis use disorder has risen from 4% pre-legalization to 10% after cannabis legalization in Ontario, according to new research.

5 Feb 2025

Existing preeclampsia risk models show deteriorating performance over time

The existing prediction models for severe complications of preeclampsia are most accurate only in the two days after hospital admission, with deteriorating performance over time, according to a new study published February 4th in the open-access journal PLOS Medicine by Henk Groen of University of Groningen, the Netherlands, and colleagues.

4 Feb 2025

$USC to lead $10.8 million study on hip fracture surgery options$

USC to lead $10.8 million study on hip fracture surgery options

The University of Southern California has been approved for $10.8 million in research funding by the Patient-Centered Outcomes Research Institute (PCORI) to compare approaches to treating older adults with a fracture of the hip.

4 Feb 2025

Researchers discover how RNA molecules influence multiple generations

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies.

4 Feb 2025

New method uses DNA sequencing for precise metabolite measurement

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars, vitamins, hormones and the hundreds of other metabolites that are critical for health.

4 Feb 2025

Acoustic voice signals aid in identifying comorbid anxiety and depression

It's no secret that there is a mental health crisis in the United States. As of 2021, 8.3% adults had major depressive disorder (MDD) and 19.1% had anxiety disorders (AD), and the COVID-19 pandemic exacerbated these statistics.

4 Feb 2025

UCLA Health receives $1.72 million grant to advance brain tumor research and training

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have been awarded a $1.72 million grant from the National Institutes of Health to support the Neuro-Oncology Translational Research Training Program, an initiative designed to train the next generation of brain tumor scientists and physician-scientists.

4 Feb 2025

International trial aims to prevent Alzheimer’s in high-risk young adults

The first participants in an international clinical trial aimed at preventing Alzheimer's disease in young adults at high risk of the disease have been enrolled.

4 Feb 2025

Study identifies most effective CBT components for treating ADHD

Attention-deficit hyperactivity disorder (ADHD) is a well-known neurodevelopmental disorder that affects the brain's ability to regulate attention and control impulses.

4 Feb 2025

New method revolutionizes body composition analysis using 3D imaging and deep learning

A recent study introduces an innovative method for analyzing body composition using advanced 3D imaging and deep learning techniques.

4 Feb 2025

Topical ABT-263 treatment improves wound healing in aging skin

A new research paper was published by Aging (Aging-US) on December 3, 2024, in Volume 17, Issue 1, titled "Topical ABT-263 treatment reduces aged skin senescence and improves subsequent wound healing."

4 Feb 2025

NTU spin-off teams up with Osler Group to offer early dementia detection tool

Nanyang Technological University, Singapore (NTU Singapore) spin-off company Gray Matter Solutions is partnering with Osler Group, a premium health and wellness organization in Singapore, to offer a new screening tool that detects mild cognitive impairment (MCI) - the early stage before dementia - efficiently and affordably using Artificial Intelligence (AI).

4 Feb 2025

Maternal stress may leave epigenetic marks on certain placental genes

Maternal stress could leave epigenetic imprints on genes in the placenta associated with cortisol — a necessary hormone for fetal development — and this would affect the baby's development from very early stages, as stated in a paper published in the journal European Neuropsychopharmacology.

4 Feb 2025