Clinical Trial News and Research

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UGA researcher develops clinical decision rule to accurately detect acute bacterial rhinosinusitis

Sinus infections are one of the most common reasons patients walk out of the doctor's office with an antibiotic prescription in hand. The problem is that bacteria causes only about one-third of sinus infections, which means most patients are inappropriately receiving antibiotics.

26 Jul 2017

Study finds no significant benefits of cooling down cardiac arrest patients for 48 hours

A five per cent difference in favor of the 48 hours. This is the result of a study from Aarhus University that has spent several years examining the possible benefits of cooling down patients suffering cardiac arrest to 33°C for 48 hours, instead of the 24-hours that is standard practice in most places.

26 Jul 2017

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Researchers from Genethon, the AFM-Telethon laboratory, Inserm (UMR 1089, Nantes) and the University of London (Royal Holloway) demonstrated the efficacy of an innovative gene therapy in the treatment of Duchenne muscular dystrophy.

25 Jul 2017

Study determines safest temperature and duration for body-cooling of newborns

After more than 20 years of research on the best treatment for full-term infants affected by oxygen deprivation during the birthing process, Seetha Shankaran, M.D., neonatologist at DMC's Children's Hospital of Michigan and Hutzel Women's Hospital, served as the lead investigator in a definitive Journal of the American Medical Association study that documented the safest depth and duration of body-cooling to minimize injury from hypoxic ischemic encephalopathy (HIE) in newborns.

25 Jul 2017

Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

Glioblastoma is a primary brain tumor with dismal survival rates, even after treatment with surgery, chemotherapy, and radiation.

25 Jul 2017

Patient navigator programs at barbershops could improve colorectal cancer screening among black men

Aging black men are at much greater risk of dying prematurely of colorectal cancer than any other group in the United States, and are less likely than their white counterparts to be diagnosed at an early stage of the disease.

25 Jul 2017

SLUCare obstetricians examine novel device to treat postpartum hemorrhage

SLUCare obstetricians are leading a clinical trial at SSM Health St. Mary's Hospital that investigates a possible approach to treat postpartum hemorrhage, the leading cause of perinatal maternal death around the world.

24 Jul 2017

Common surgical techniques for ACL repair offer improved quality of life five years after injury

The most common surgical techniques used to repair a torn anterior cruciate ligament (ACL) offer patients improved quality of life five years after injury, according to research presented today at the American Orthopedic Society for Sports Medicine's Annual Meeting in Toronto, Ontario, Canada.

21 Jul 2017

New genomic research partnership promises to redefine and transform cancer treatment

Personalized cancer therapies are on the horizon thanks to a new genomic cancer research partnership between the Gene Editing Institute of Christiana Care Health System's Helen F. Graham Cancer Center & Research Institute and the biotechnology company NovellusDx.

21 Jul 2017

Doctors appear to have reached unexpected consensus in prescribing pediatric anti-seizure medications

The number of available anti-seizure medications has exploded in the past two decades, going from just a handful of medicines available in the 1990s to more than 20 now.

19 Jul 2017

Latinos left out of clinical trials … and possible cures

Two decades ago, Luis Antonio Cabrera received devastating news: He likely had only three months to live.

19 Jul 2017

GOP failure to replace the health law was years in the making

Seven years of Republican vows to "repeal and replace" the Affordable Care Act came to a crashing halt Tuesday, when it became clear that the Senate could not muster the necessary votes for any of three separate proposals that have been under consideration.

18 Jul 2017

Insomnia research by SleepCogni receives continued funding

As part of a collaborative R&D program, the UK’s Innovation agency have co-funded SleepCogni’s exciting research and development into helping resolve the global epidemic of insomnia.

18 Jul 2017

Developing software for cell and gene therapy supply chain tracking

The first thing is, to always remember that we're dealing with a living drug, cells, which are very sensitive to environmental conditions, such as temperature and humidity etc. All of those things can impact on the viability of the drug and its effectiveness.

18 Jul 2017

Study identifies potential treatment for fetal alcohol spectrum disorder

Two commonly used drugs erased the learning and memory deficits caused by fetal alcohol exposure when the drugs were given after birth, thus potentially identifying a treatment for the disorder, reports a new Northwestern Medicine study.

18 Jul 2017

Study: Team-based primary care model effective in lowering opioid use among chronic pain patients

A new, team-based, primary care model is decreasing prescription opioid use among patients with chronic pain by 40 percent, according to a new study out of Boston Medical Center's Grayken Center for Addiction Medicine, which is published online ahead of print in JAMA Internal Medicine.

18 Jul 2017

NIH researchers show how investigational drug works against rare, fatal genetic disease

Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1).

17 Jul 2017

Study: Breast cancer patients receiving neoadjuvant radiation have lower risk of second primary tumor

Moffitt Cancer Center researchers launched a first of its kind study comparing the long-term benefits of radiation therapy in women with breast cancer either before surgery (neoadjuvant) or after surgery (adjuvant).

17 Jul 2017

Regular word puzzle use linked to better brain function in later life

The more regularly people report doing word puzzles such as crosswords, the better their brain function in later life, a large-scale and robust online trial has found.

17 Jul 2017

Study to examine how improvisational dance can help people with dementia

Depending on what generation you belong to, the term "improvisational dance" may conjure up images of beatniks grooving to the beat of bongos in a darkened coffeehouse or the black-clad Dieter gyrating to techno pop in a Sprockets sketch on "Saturday Night Live".

14 Jul 2017

Clinical Trial News and Research

UGA researcher develops clinical decision rule to accurately detect acute bacterial rhinosinusitis

Study finds no significant benefits of cooling down cardiac arrest patients for 48 hours

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Study determines safest temperature and duration for body-cooling of newborns

Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

Patient navigator programs at barbershops could improve colorectal cancer screening among black men

SLUCare obstetricians examine novel device to treat postpartum hemorrhage

Common surgical techniques for ACL repair offer improved quality of life five years after injury

New genomic research partnership promises to redefine and transform cancer treatment

Doctors appear to have reached unexpected consensus in prescribing pediatric anti-seizure medications

Latinos left out of clinical trials … and possible cures

GOP failure to replace the health law was years in the making

Insomnia research by SleepCogni receives continued funding

Developing software for cell and gene therapy supply chain tracking

Study identifies potential treatment for fetal alcohol spectrum disorder

Study: Team-based primary care model effective in lowering opioid use among chronic pain patients

NIH researchers show how investigational drug works against rare, fatal genetic disease

Study: Breast cancer patients receiving neoadjuvant radiation have lower risk of second primary tumor

Regular word puzzle use linked to better brain function in later life

Study to examine how improvisational dance can help people with dementia

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