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New inhaled treatment may lead to self-administered therapy for COVID-19

An inhaled treatment against the SARS-CoV-2 virus may lead to a future self-administered therapy for COVID-19, the pandemic that has killed more than 1 million people worldwide.

20 Oct 2020

Adult stem cell-based lung organoid models emulate host immune response in fatal COVID-19

Recently, a team of researchers from the University of California San Diego and The Scripps Research Institute, CA, USA, showed that an integrated stem cell-based disease modeling and computational approach is crucial for simulating the host immune response in fatal COVID-19 patients.

19 Oct 2020

Promising interim results for Sinopharm's inactivated whole-virion SARS-CoV-2 vaccine

The COVID-19 pandemic has led to intensive scientific efforts to bring about an effective vaccine for global distribution. Many different vaccine design approaches are underway. A recent study published in the journal The Lancet Infectious Diseases in October 2020 reports a potentially successful inactivated virus vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

19 Oct 2020

Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

Now, a new study presented on the preprint server bioRxiv in October 2020 describes the efficient design of an mRNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), based on the use of the viral receptor-binding domain (RBD) mRNA encapsulated in lipid nanoparticles (LNP).

19 Oct 2020

Antigenic imprinting of sarbecovirus

A recent study published on the preprint server bioRxiv* in October 2020 shows that the design of a vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) must consider the prior history of exposure to coronaviruses since these affect the antibody response to the virus.

19 Oct 2020

Study finds direct link between physical fitness, cognitive performance, and optimal nutrition

Researchers at the University of Illinois, Urbana-Champaign, Abbott and, the U.S. Air Force Research Lab announced today the results of a new study that found a direct link between physical fitness, cognitive performance, and optimal nutrition.

19 Oct 2020

Student adherence to control measures could significantly reduce COVID-19 risk

Researchers at the University of Warwick in the UK have conducted a modeling study showing that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could readily spread among students in the university setting if non-pharmaceutical interventions (NPIs) are not properly adhered to.

19 Oct 2020

New device rapidly transfers delicate tissue or electronic sheets to patients

Thin tissue grafts and flexible electronics have a host of applications for wound healing, regenerative medicine and biosensing.

19 Oct 2020

Dolutegravir is a first-line treatment for people newly diagnosed with HIV

A new study by UBC researchers is set to change international treatment recommendations for people who are newly diagnosed with HIV--an update that could affect nearly two million people per year worldwide.

19 Oct 2020

WHO study finds Remdesivir and other repurposed drugs ineffective in COVID-19

A large-scale randomized trial has recently been conducted by the World Health Organization (WHO) to evaluate the efficacy of four repurposed antiviral medicines, including Remdesivir, Hydroxychloroquine, Lopinavir, and Interferon, currently used to treat hospitalized coronavirus disease 2019 (COVID-19) patients.

18 Oct 2020

Adhesive plastic film inactivates novel coronavirus on contact

An adhesive plastic film designed to protect surfaces such as doorknobs, handrails, elevator buttons, and touch screens inactivates the novel coronavirus on contact.

16 Oct 2020

Antispastic drug candidate could offer new hope for millions of patients suffering from spasticity

First-in-class antispastic drug candidate to reach clinical phase is published in the prestigious life science journal, Cell. Drug candidate MPH-220 could mean new hope for millions of patients suffering from spasticity.

16 Oct 2020

Experimental ALS drug shows potential to prolong patient survival

An experimental medication that was recently shown to slow the progression of the neurodegenerative disease amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, has now demonstrated the potential to also prolong patient survival.

16 Oct 2020

Plant genetic engineering to sustainably address micronutrient malnutrition

More than two billion people worldwide suffer from micronutrient malnutrition due to deficiencies in minerals and vitamins.

16 Oct 2020

NIH launches adaptive Phase 3 clinical trial to test immune modulator drugs in COVID-19 patients

The National Institutes of Health has launched an adaptive Phase 3 clinical trial to evaluate the safety and efficacy of three immune modulator drugs in hospitalized adults with COVID-19.

16 Oct 2020

Antibody levels drop rapidly in recovering COVID-19 patients, shows study

In the absence of approved, effective treatments for COVID-19, some hospitals have been treating patients with severe COVID symptoms with blood plasma from recovering patients.

16 Oct 2020

New article explores the endemic potential of COVID-19 virus

A new article by Columbia Mailman School researchers Jeffrey Shaman and Marta Galanti explores the potential for the COVID-19 virus to become endemic, a regular feature producing recurring outbreaks in humans.

16 Oct 2020

Scientists discover a novel antiviral strategy for treating COVID-19

A research team led by Professor Hongzhe SUN, Norman & Cecilia Yip Professor in Bioinorganic Chemistry, Department of Chemistry, Faculty of Science, and Professor Kwok Yung YUEN, Henry Fok Professor in Infectious Diseases, Department of Microbiology, Li Ka Shing Faculty of Medicine of the University of Hong Kong (HKU), has discovered a novel antiviral strategy for treatment of COVID-19.

16 Oct 2020

Study: Combining sound and electrical stimulation of tongue can reduce tinnitus

In the largest clinical trial of its kind, researchers show that combining sound and electrical stimulation of the tongue can significantly reduce tinnitus, commonly described as "ringing in the ears." They also found that therapeutic effects can be sustained for up to 12 months post-treatment.

16 Oct 2020

REFLECT II clinical trial evaluates safety and efficacy of cerebral embolic deflection filter

The REFLECT II randomized clinical trial evaluating the safety and efficacy of a device designed to reduce cerebral embolization and ischemic stroke, complications of transcatheter aortic valve replacement (TAVR), found that the device met the primary safety endpoint compared to historical controls but did not demonstrate superiority of the device for the primary hierarchical efficacy endpoint.

16 Oct 2020