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Junk genes could one day offer framework for treating people with familial hypercholesterolemia

Scientists from UCLA and the Howard Hughes Medical Institute successfully used a gene that suppresses cholesterol levels as part of a treatment to reduce plaque in mice with a disorder called familial hypercholesterolemia.

26 Aug 2017

Collaborative project reaches milestone halfway point in constructing Kinase Chemogenomic Set

The Structural Genomics Consortium at the University of North Carolina at Chapel Hill (SGC-UNC), in partnership with the DiscoverX Corporation, has reached the milestone halfway point in its development of the Kinase Chemogenomic Set, a potent group of inhibitors which allow deeper exploration of the human kinome, a family of enzymes critical to understanding human disease and developing new therapies.

26 Aug 2017

Distinguishing biothreat look-alikes could aid biological surveillance

Biological "detectives" are tracking down biothreats such as the bacteria that causes tularemia ("rabbit fever"), but they constantly face the challenge of avoiding false positives.

26 Aug 2017

Pan-European initiative receives €3.7 million funding to train next generation of brain tumor researchers

A pan-European initiative led by the University of Plymouth designed to train the next generation of brain tumor researchers, has received funding of almost €3.7 million from the European Commission's Horizon 2020 - Research and Innovation Framework Program.

26 Aug 2017

Scientists develop new system to identify and characterize regulatory DNA sequences

Scientists from the Children's Medical Center Research Institute at UT Southwestern have developed an innovative system to identify and characterize the molecular components that control the activities of regulatory DNA sequences in the human genome.

24 Aug 2017

Long non-coding RNAs could represent novel male infertility drug targets

Scientists have found distinctive portions of genetic material--known as lncRNAs--that help sperm develop. Male mice lacking a particular lncRNA have low sperm count, suggesting lncRNAs could represent novel infertility drug targets.

24 Aug 2017

Researchers aim to develop dynamic therapeutics for combating antiviral drug resistance

Antiviral drug resistance has long been a problem in modern society. As viruses evolve, they develop resistance to antiviral drugs, which become less effective at treating diseases such as influenza.

24 Aug 2017

Variations in ancient mitochondrial DNA may play key role in predisposition to ASD

Mitochondria, the tiny structures inside our cells that generate energy, may play a key role in autism spectrum disorders (ASD).

23 Aug 2017

New international research project identifies subtypes of ocular melanoma

A new international research project, involving the University of Liverpool's leading eye cancer research group, has identified specific subtypes of ocular melanoma that will help develop improved management strategies and therapies in the future.

23 Aug 2017

Researchers describe mechanism linking HPV infection and cancer

Infection with human papillomavirus (HPV) is the primary cause of cervical cancer and a subset of head and neck cancers worldwide.

23 Aug 2017

Study findings could one day help doctors better predict survival of liver cancer patients

A new study of a molecule that regulates liver-cell metabolism and suppresses liver-cancer development shows that the molecule interacts with thousands of genes in liver cells, and that when levels of the molecule go down, which often happens during liver-cancer development, the activity of certain cancer-promoting genes goes up.

23 Aug 2017

Id genes found to play crucial role in heart development

Researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), the Cardiovascular Institute at Stanford University and other institutions were surprised to discover that the four genes in the Id family play a crucial role in heart development, telling undifferentiated stem cells to form heart tubes and eventually muscle.

22 Aug 2017

JAX wins NIGMS funding to decipher role of RNA structure in gene regulation

With new funding from the National Institute of General Medical Sciences totaling $2,059,618 over five years, JAX Assistant Professor Zhengqing Ouyang, Ph.D., will build a research program to reveal the roles of RNA structure in post-transcriptional regulation at the genome scale.

21 Aug 2017

Penn researchers receive two new post-doctoral training grants for genomic science

Researchers from the Perelman School of Medicine at the University of Pennsylvania have received two highly competitive post-doctoral Institutional Training Grants for genomic science from the National Human Genome Research Institute of the National Institutes of Health.

21 Aug 2017

Researchers discover potential way to trigger regeneration, repair of damaged heart cells

New research has discovered a potential means to trigger damaged heart cells to self-heal. The discovery could lead to groundbreaking forms of treatment for heart diseases.

21 Aug 2017

Northwestern Medicine scientists develop novel method to track HIV infection

Northwestern Medicine scientists have developed a novel method of tracking HIV infection, allowing the behavior of individual virions -- infectious particles -- to be connected to infectivity.

18 Aug 2017

New research suggests cell immortalization as more complicated process than originally thought

A mutation that helps make cells immortal is critical to the development of a tumor, but new research at the University of California, Berkeley suggests that becoming immortal is a more complicated process than originally thought.

18 Aug 2017

Study elucidates how aerobic exercise protects the sick heart

Regular exercise is considered an important form of treatment for heart failure, a condition in which the heart is unable to pump enough blood to meet the body's needs.

18 Aug 2017

Researchers get closer to creating new blood test that can identify breast cancer brain metastasis

Houston Methodist cancer researchers are now closer to creating a blood test that can identify breast cancer patients who are at increased risk for developing brain metastasis, and also monitor disease progression and response to therapy in real time.

17 Aug 2017

Novel blood test identifies tumor-derived DNA in early-stage cancer patients

In a bid to detect cancers early and in a noninvasive way, scientists at the Johns Hopkins Kimmel Cancer Center report they have developed a test that spots tiny amounts of cancer-specific DNA in blood and have used it to accurately identify more than half of 138 people with relatively early-stage colorectal, breast, lung and ovarian cancers.

17 Aug 2017

Genome News and Research

Junk genes could one day offer framework for treating people with familial hypercholesterolemia

Collaborative project reaches milestone halfway point in constructing Kinase Chemogenomic Set

Distinguishing biothreat look-alikes could aid biological surveillance

Pan-European initiative receives €3.7 million funding to train next generation of brain tumor researchers

Scientists develop new system to identify and characterize regulatory DNA sequences

Long non-coding RNAs could represent novel male infertility drug targets

Researchers aim to develop dynamic therapeutics for combating antiviral drug resistance

Variations in ancient mitochondrial DNA may play key role in predisposition to ASD

New international research project identifies subtypes of ocular melanoma

Researchers describe mechanism linking HPV infection and cancer

Study findings could one day help doctors better predict survival of liver cancer patients

Id genes found to play crucial role in heart development

JAX wins NIGMS funding to decipher role of RNA structure in gene regulation

Penn researchers receive two new post-doctoral training grants for genomic science

Researchers discover potential way to trigger regeneration, repair of damaged heart cells

Northwestern Medicine scientists develop novel method to track HIV infection

New research suggests cell immortalization as more complicated process than originally thought

Study elucidates how aerobic exercise protects the sick heart

Researchers get closer to creating new blood test that can identify breast cancer brain metastasis

Novel blood test identifies tumor-derived DNA in early-stage cancer patients

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