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Pheno Therapeutics granted clinical trial authorization for lead multiple sclerosis therapeutic candidate PTD802

Pheno Therapeutics Limited., a biotechnology company focused on the discovery and development of small molecule therapeutics for the treatment of neurological diseases, announced today it has received clinical trial authorization (CTA) from the UK’s MHRA (Medicines and Healthcare products Regulatory Agency) for its lead candidate, PTD802.

From Pheno Therapeutics 15 Jan 2025

The role of inflammation in the pathogenesis of heart failure

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Cardiovascular disease remains a leading cause of death and disability worldwide. Heart failure (HF) is the end stage of various cardiovascular diseases. Despite recent advancements in understanding of HF pathogenesis and treatment, the prognosis of patients with HF remains poor.

15 Jan 2025

New research sheds light on changing liver cancer trends

Liver cancer is a leading cause of cancer-related deaths worldwide, with distinct geographic patterns in its incidence.

13 Jan 2025

By 2060, 1 million U.S. adults are projected to develop dementia annually

The lifetime risk of dementia is 42%, with significant variations by race and sex, underscoring the importance of public health strategies for prevention.

13 Jan 2025

Totally implantable cochlear implant promises a new era of hearing restoration

Scientists have developed a totally implantable cochlear implant that delivers hearing performance comparable to conventional devices while improving quality of life and eliminating the need for external components.

12 Jan 2025

UTHealth project aims to improve clinical trials for underserved people with neurological conditions

In an effort to close the gap in neurological outcomes for underserved populations, a UTHealth Houston project funded with $2.9 million from the National Institutes of Health (NIH) will engage community partners to improve the design of clinical trials.

10 Jan 2025

Hebrew SeniorLife launches trial to explore probiotics and prebiotics for bone health

Hinda and Arthur Marcus Institute for Aging Research investigators at Hebrew SeniorLife have launched a large clinical food trial to test whether a combination of probiotics and prebiotics (BondiaÒ or SBD111) developed by Solarea Bio will help manage bone health in women aged 60 years and above.

10 Jan 2025

Hormonal changes after menopause impact multiple sclerosis severity

A new study by UC San Francisco has found that menopause revs up the progression of multiple sclerosis (MS).

10 Jan 2025

Exploring the link between housing and health in autistic populations

Affordable and stable housing is critical to improving health across a person's lifespan. People with disabilities, including autism, comprise a significant share of people in need of housing assistance. However, the intersection of housing and health among individuals with autism is largely unknown because data on public housing and public health are not connected.

9 Jan 2025

Key actions identified to improve post-acute care for TBI patients

A new systematic literature search identified the highest priority clinical actions aimed at improving post-acute care for non-hospitalized traumatic brain injury (TBI). The study is published in the peer-reviewed Journal of Neurotrauma.

7 Jan 2025

Concussions may trigger Alzheimer's symptoms through latent viruses

Concussions and repetitive head trauma in sports like football and boxing, once accepted as an unpleasant consequence of intense athletic competition, are now recognized as serious health threats.

7 Jan 2025

Sugar-sweetened drinks linked to 1 in 10 new diabetes cases

The consumption of sugar-sweetened beverages is driving millions of diabetes and heart disease cases worldwide, with significant regional health inequalities.

7 Jan 2025

Persistent and increasing depression linked to higher mortality risk in Chinese adults

Study reveals five depressive symptom trajectories, with stable-high and increasing patterns significantly raising all-cause mortality risk in older adults.

7 Jan 2025

Fracture Liaison Services crucial for addressing global osteoporosis challenges

A new Perspective article published in the New England Journal of Medicine emphasizes the critical role of Fracture Liaison Services (FLS) in addressing the growing global burden of osteoporosis-related fractures, particularly hip fractures.

6 Jan 2025

University of Birmingham receives £3.5 million to study arthritis treatment responses

In recent years treatment with powerful biologic and targeted synthetic therapies has changed the landscape for arthritis, but currently finding the right treatment for each person is a matter of trial and error.

6 Jan 2025

Yale study identifies molecular mechanism behind some lissencephaly disorders

Lissencephaly is a spectrum of rare, genetic disorders in which the brain fails to develop its hallmark folds.

2 Jan 2025

LGBTQ+ people relive old traumas as they age on their own

Bill Hall, 71, has been fighting for his life for 38 years. These days, he's feeling worn out.

24 Dec 2024

New migraine drug atogepant shows quick relief

A drug recently approved to prevent migraine may start working right away, according to a study published in the December 23, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 Dec 2024

COVID-19 infection not associated with worsening MS symptoms or disability

For people with multiple sclerosis (MS), having a COVID-19 infection is not associated with worsening MS symptoms or disability, according to a study published in the December 23, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 Dec 2024

Lithium shows promise as a potential therapy for autism spectrum disorder

A groundbreaking discovery has highlighted lithium - a drug long used to treat bipolar disorder and depression - as a potential therapy for autism spectrum disorder (ASD).

23 Dec 2024