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Vitamin E significantly improves liver health in MASH patients, new study finds

A 96-week clinical trial found that 300 mg of Vitamin E significantly improved liver histology and reduced inflammation in patients with MASH, with no major safety concerns reported.

19 Feb 2025

Novel classification system for SJS/TEN aims to improve patient care

First identified by Stevens and Johnson in 1922, SJS and TEN are now recognized as disorders with a continuum of severity, from milder forms (SJS) to the most severe (TEN).

19 Feb 2025

Cancer cells cooperate to source nutrients and support tumor growth

Cancer cells work together to source nutrients from their environment-a cooperative process that was previously overlooked by scientists but may be a promising target for treating cancer.

19 Feb 2025

Genetic mutation linked to schizophrenia in both humans and mice

A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with the same mutation, a rare finding of a direct genetic link to psychosis, report researchers at the University of Illinois Urbana-Champaign and colleagues in Massachusetts and Germany.

19 Feb 2025

Neuroestrogens likely contribute to appetite regulation

Although a woman's ovaries produce the most estrogen, various types of estrogen are also synthesized throughout different tissues in the body, including the brain's neurons.

19 Feb 2025

Cholesterol metabolite linked to Parkinson's disease development in mice

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice.

18 Feb 2025

Study links sucrase defects to increased IBS risk and severe symptoms

Sucrase-isomaltase (SI) is an intestinal enzyme critical for the digestion of dietary carbohydrates, particularly sucrose and starch.

17 Feb 2025

New gene switch may lead to precise treatments for metabolic diseases

ETH researchers have developed a new gene switch that can be activated using a commercially available nitroglycerine patch applied to the skin.

17 Feb 2025

Dead bacteria offer nutrients to neighbors through evolved enzyme

Darwin's theory of natural selection provides an explanation for why organisms develop traits that help them survive and reproduce.

14 Feb 2025

New biomarker can accurately predict outcomes in meningiomas and breast cancers

Using a new technology and computational method, researchers from Fred Hutch Cancer Center and The University of Texas MD Anderson Cancer Center have uncovered a biomarker capable of accurately predicting outcomes in meningioma brain tumors and breast cancers.

13 Feb 2025

Enzyme found in lymphatic cells enhances immune activity against tumors

When a tumor develops, it creates a structure around itself called the tumor stroma, within which blood and lymphatic vessels ensure nutritional and respiratory biological exchanges.

13 Feb 2025

Study explains why tecovirimat fails against some mpox strains

A virus originally found in animals, mpox – which causes the disease of the same name – is now circulating in humans.

13 Feb 2025

Gut bacteria could one day serve as microscopic in-house pharmacists

Hundreds of different species of microbes live, laugh, and love in your gut. In the future, one of these might serve a new function: microscopic in-house pharmacist.

13 Feb 2025

Could a common sugar in processed foods be fueling childhood liver disease?

Researchers found that high fructose intake, especially from processed foods, is linked to metabolic dysfunction-associated steatotic liver disease (MASLD) in children with obesity, with potential misreporting of sugary food sources.

12 Feb 2025

Targeting PAK5 could offer new therapeutic approach for endometriosis

Endometriosis, a prevalent gynecological condition, is characterized by the growth of endometrial-like tissues outside the uterus, leading to severe pain and infertility in affected women.

11 Feb 2025

Alzheimer’s escape: How one man defied his genetic fate for nearly two decades

A groundbreaking study reveals how a rare combination of genetics, proteomics, and environmental factors may hold the key to delaying or preventing Alzheimer's, challenging long-held assumptions about the disease.

11 Feb 2025

One shot to lower cholesterol for life? Scientists unlock a groundbreaking gene therapy

Researchers developed an epigenetic editing approach to silence the PCSK9 gene, achieving long-term cholesterol reduction without altering DNA, offering a potential one-time treatment for high cholesterol.

11 Feb 2025

Daily fruit and vegetable extracts may boost brain power

A study reveals polyphenol-rich nutraceuticals enhance cognitive performance and boost neuroprotective biomarkers, offering a dietary approach to brain health.

11 Feb 2025

Breakthrough study identifies new way to address Alzheimer's at early stages

A team of researchers from the Keck School of Medicine of USC has unlocked the details of a cellular pathway that triggers cellular inflammation and aging and is linked to Alzheimer's disease, particularly among those who carry the APOE4 genetic risk.

10 Feb 2025

GUK1 enzyme plays crucial role in lung cancer metabolism and growth

Lung cancer is a particularly challenging form of cancer. It often strikes unexpectedly and aggressively with little warning, and it can shapeshift in unpredictable ways to evade treatment.

10 Feb 2025