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Understanding how long non-coding RNAs control gene expression in cancer

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed.

5 Aug 2025

Researchers discover amyloid protein buildup in bone marrow of aging mice

A recent study led by a team of researchers at The Johns Hopkins University School of Medicine examining aging mice has provided what is believed to be the first evidence that amyloid beta protein-small, sticky protein fragment found in people with Alzheimer's disease (AD)-particles build up in the bone marrow of the animals, although not in the exact same form as the large, dense plaques found in the brains of people with Alzheimer's disease.

5 Aug 2025

'Two-in-one' RNA molecule can simultaneously turn off two difficult-to-target cancer-related genes

University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a "two-in-one" molecule that can simultaneously turn off two notoriously difficult-to-target cancer-related genes, KRAS and MYC, as well as directly deliver drugs to tumors that express these genes.

4 Aug 2025

New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025

New insights reveal how sugar metabolism protects neurons from degeneration

Unlike most cells in the human body, neurons-the functional cells of our nervous system-cannot typically replace themselves with healthy copies after being damaged.

4 Aug 2025

Immune molecule found to play a key role in regulating inflammation in rheumatoid arthritis

Researchers at Kyoto University have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis (RA).

1 Aug 2025

Mapping the brain’s serotonin switch could lead to better antidepressants

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights into how a critical brain receptor works at the molecular level and why that matters for mental health treatments.

1 Aug 2025

New approach preserves insulin-producing cells in diabetes model

Scientific breakthroughs in one disease don't always shed light on treating other diseases. But that's been the surprising journey of one Mayo Clinic research team.

1 Aug 2025

AI-designed protein activates Notch signaling pathway to boost T-cell production

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in T-cell development and function.

1 Aug 2025

The vicious circle of aging and metabolic dysfunction-associated steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) and aging are locked in a vicious circle: senescence of liver cells accelerates fat accumulation, inflammation and fibrosis, while chronic steatosis in turn hastens hepatic decline.

1 Aug 2025

Virtual memory T cells provide nonspecific immunity for infants early in life

Findings from St. Jude Children's Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life.

31 Jul 2025

New treatment shows promise in protecting brain following stroke reperfusion

Cambridge scientists have developed and tested a new drug in mice that has the potential to reduce damage to the brain when blood flow is restored following a stroke.

31 Jul 2025

Can stacking creatine and β-alanine give you extra gains? Here’s what science says

Co-supplementation with creatine and β-alanine may enhance high-intensity exercise performance, especially in repeated short bursts. However, it offers no additional benefit over creatine alone for maximal strength, aerobic capacity, or body composition.

30 Jul 2025

Canadian scientists trap gut microbe fuel to improve blood sugar and liver health

A team of Canadian scientists has discovered a surprising new way to improve blood sugar levels and reduce liver damage: by trapping a little-known fuel made by gut bacteria before they wreak havoc on the body.

30 Jul 2025

PD-1 helps guide immune memory cells to the skin early during infection

Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune defenders in the skin.

30 Jul 2025

Innovative nanopore system enables controlled DNA unzipping

DNA holds the instructions that make us who we are. If we want to read those instructions, say to understand our predisposition to genetic disorders, we need to carefully 'unzip' DNA's iconic double-helix structure.

30 Jul 2025

Pyruvate identified as a promising oral treatment for ulcerative colitis

Ulcerative colitis (UC) is a chronic inflammatory disease marked by intestinal pain, bleeding, and impaired gut barrier function.

29 Jul 2025

Microcone-enhanced microfluidic device captures circulating tumor cells efficiently

Circulating tumor cells (CTCs) refer to cancer cells that have broken off from a primary tumor. These tumor cells can travel through the blood in the circulatory system and lodge themselves in other organs to cause secondary tumors.

29 Jul 2025

Artificial protein sensor offers new way to measure cortisol with a smartphone

Cortisol is a crucial hormone that regulates many important bodily functions like blood pressure and metabolism, and imbalances of this stress hormone can lead to health problems.

29 Jul 2025

Centauri Therapeutics receives an additional $5.1 M from CARB-X to progress ABX-01 lead compound to first in human clinical trials

Centauri Therapeutics Limited ('Centauri'), an immunotherapy company with a unique and proprietary platform technology applicable across a wide range of therapeutic indications, announced today that CARB-X (Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator) has provided an additional $5.1 M in funding for the development of their lead compound.

29 Jul 2025

Molecule News and Research

Understanding how long non-coding RNAs control gene expression in cancer

Researchers discover amyloid protein buildup in bone marrow of aging mice

'Two-in-one' RNA molecule can simultaneously turn off two difficult-to-target cancer-related genes

New treatment approach developed to prevent lupus nephritis

New insights reveal how sugar metabolism protects neurons from degeneration

Immune molecule found to play a key role in regulating inflammation in rheumatoid arthritis

Mapping the brain’s serotonin switch could lead to better antidepressants

New approach preserves insulin-producing cells in diabetes model

AI-designed protein activates Notch signaling pathway to boost T-cell production

The vicious circle of aging and metabolic dysfunction-associated steatotic liver disease

Virtual memory T cells provide nonspecific immunity for infants early in life

New treatment shows promise in protecting brain following stroke reperfusion

Can stacking creatine and β-alanine give you extra gains? Here’s what science says

Canadian scientists trap gut microbe fuel to improve blood sugar and liver health

PD-1 helps guide immune memory cells to the skin early during infection

Innovative nanopore system enables controlled DNA unzipping

Pyruvate identified as a promising oral treatment for ulcerative colitis

Microcone-enhanced microfluidic device captures circulating tumor cells efficiently

Artificial protein sensor offers new way to measure cortisol with a smartphone

Centauri Therapeutics receives an additional $5.1 M from CARB-X to progress ABX-01 lead compound to first in human clinical trials

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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