Therapeutics News and Research

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CRISPR-based therapeutic approach designed to treat fatal pediatric disease

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood.

11 Sep 2025

Antibody cocktail could change the way the world fights influenza

An unusual therapy developed at The Jackson Laboratory (JAX) could change the way the world fights influenza, one of the deadliest infectious diseases.

11 Sep 2025

Novel method accurately identifies therapeutic antibodies to treat infectious diseases

Scientists at Scripps Research have developed a novel method that uses artificial intelligence (AI) and advanced imaging techniques to more accurately and efficiently identify therapeutic antibodies to treat infectious diseases.

10 Sep 2025

Lung tumors rewire immune cells in the bone marrow before they reach cancer sites

Lung tumors don't just evade the immune system. They reshape it at its source. Researchers from the Icahn School of Medicine at Mount Sinai and collaborators report in the September 10 online issue of Nature that tumors rewire immune cells in the bone marrow before they even reach the cancer, suggesting a new target to enhance the durability of current immunotherapy

10 Sep 2025

New tool helps identify risky medications for older cancer patients

New research published in the September 2025 issue of JNCCN-Journal of the National Comprehensive Cancer Network validates the use of a specifically-curated tool for determining which medications may be causing harm for older patients with cancer.

10 Sep 2025

Specific microbial changes linked to poor growth in children

Malnutrition is responsible for more than half of all deaths in children under the age of five worldwide.

10 Sep 2025

New technique used to conduct real-time measurement of boron in live tumor cells

A new technique has measured boron in individual cancer cells for the first time, enabling researchers to better understand how drugs act to kill tumors in some cancers.

10 Sep 2025

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

Nina Kumowski, MD, of the Department of Radiology and Center for Systems Biology at Massachusetts General Hospital, is the lead author and Matthias Nahrendorf, MD, PhD of the Department of Radiology and Center for Systems Biology at MGH, is the senior author of a paper published in Science, "Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia."

9 Sep 2025

New strategy for difficult-to-treat mesothelioma: Immunotherapy and ctDNA insights

People with operable diffuse pleural mesothelioma may benefit from immunotherapy before and after surgery, based on results of a clinical trial exploring the sequence of treatment and the role of surgery for this difficult to treat cancer.

8 Sep 2025

New drug candidate STF 1623 activates innate immunity in solid tumors

Cancer immunotherapy, which primes the body's immune system to fight off tumors, has historically focused on harnessing T cells' natural ability to recognize and attack cancer cells.

5 Sep 2025

WHO expands essential medicines lists with new cancer and diabetes treatments

Today, the World Health Organization (WHO) has released updated editions of its Model Lists of Essential Medicines (EML) and Essential Medicines for Children (EMLc), adding new treatments for various types of cancer and for diabetes with associated comorbidities such as obesity.

5 Sep 2025

Targeting metabolic reprogramming to overcome immune suppression in head and neck cancer

Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year.

5 Sep 2025

Oncolytic viruses integrated with immunotherapy for next-generation cancer treatment

The integration of oncolytic viruses (OVs) with immunotherapy is reshaping the landscape of tumor treatment, offering new hope for patients.

5 Sep 2025

Natural medicines as emerging tools to target the tumor vascular microenvironment

Recent advances in cancer treatment highlight the potential of natural medicines to target the tumor vascular microenvironment, offering a novel strategy to inhibit tumor growth and metastasis.

5 Sep 2025

Streamlining CAR T cell production through in vivo therapeutic strategies

This review article highlights the transformative potential of in vivo CAR T cell therapy in addressing the limitations of traditional CAR T cell production.

5 Sep 2025

Innovative approach advances equity in health care AI

A team of researchers at the Icahn School of Medicine at Mount Sinai has developed a new method to identify and reduce biases in datasets used to train machine-learning algorithms-addressing a critical issue that can affect diagnostic accuracy and treatment decisions.

5 Sep 2025

BioDlink expands ecosystem alliance to empower biotech innovators worldwide

As BioDlink, a leading global CDMO, affirms its commitment to strategic alliances to support biotech innovation worldwide as it marks 15 years of operations.

From BioDlink 5 Sep 2025

HER2 and CD24 emerge as promising radiotheranostic targets in endometrial cancer

Two molecular targets-human epidermal growth factor 2 (HER2) and cluster of differentiation 24 (CD24)-are highly promising candidates for new nuclear diagnostics and therapeutics for endometrial cancer, according to new research published in The Journal of Nuclear Medicine.

5 Sep 2025

Single hair strand reveals elemental patterns linked to ALS

Researchers at the Icahn School of Medicine at Mount Sinai have shown for the first time that a single strand of hair can reveal unique elemental patterns that distinguish people with amyotrophic lateral sclerosis (ALS) from healthy individuals.

4 Sep 2025

Breakthrough technology enables faster and cheaper antibody analysis

Antibodies are the critical targeting agents of the immune system and the crux of immune therapy and vaccine development, but studying them is slow, expensive and labor-intensive.

4 Sep 2025

Therapeutics News and Research

CRISPR-based therapeutic approach designed to treat fatal pediatric disease

Antibody cocktail could change the way the world fights influenza

Novel method accurately identifies therapeutic antibodies to treat infectious diseases

Lung tumors rewire immune cells in the bone marrow before they reach cancer sites

New tool helps identify risky medications for older cancer patients

Specific microbial changes linked to poor growth in children

New technique used to conduct real-time measurement of boron in live tumor cells

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

New strategy for difficult-to-treat mesothelioma: Immunotherapy and ctDNA insights

New drug candidate STF 1623 activates innate immunity in solid tumors

WHO expands essential medicines lists with new cancer and diabetes treatments

Targeting metabolic reprogramming to overcome immune suppression in head and neck cancer

Oncolytic viruses integrated with immunotherapy for next-generation cancer treatment

Natural medicines as emerging tools to target the tumor vascular microenvironment

Streamlining CAR T cell production through in vivo therapeutic strategies

Innovative approach advances equity in health care AI

BioDlink expands ecosystem alliance to empower biotech innovators worldwide

HER2 and CD24 emerge as promising radiotheranostic targets in endometrial cancer

Single hair strand reveals elemental patterns linked to ALS

Breakthrough technology enables faster and cheaper antibody analysis

Industry Focus eBook - Microbiome (1st edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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