Respiratory News and Research

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The comparative effectiveness of neutralizing monoclonal antibodies against SARS-CoV-2

A study investigated the comparative efficacy of neutralizing monoclonal antibodies against SARS-CoV-2.

13 Sep 2021

An oral COVID-19 vaccine induces mucosal and protective immunity

Researchers have collaborated to resolve the aforementioned problems associated with injection vaccines to create a thermostable vaccine that can be taken orally.

13 Sep 2021

The rate of vaccine-induced heart inflammation in children

In a paper uploaded to the preprint server medRxiv*, a risk-benefit analysis was undertaken utilizing data collected from VAERS relating to adolescents having received an mRNA vaccine before June 18th 2021.

13 Sep 2021

Australia's response to COVID-19 pandemic

In a recent paper, Australia's response to the COVID-19 pandemic is described, identifying the factors that contributed most to the countries success.

13 Sep 2021

Low-dose CT lung cancer screening linked to reduction in lung cancer mortality

Low-dose CT lung cancer screening is associated with a 16 percent relative reduction in lung cancer mortality, when compared against a non-LDCT control arm, according to research presented by Professor John Field and the United Kingdom Cancer Screening Trial (UKLS) Team today at the IASLC 2021 World Conference on Lung Cancer. The research will be published in the Lancet Regional Health-Europe.

13 Sep 2021

Discovery of diverse sarbecovirus broadly neutralizing antibodies from SARS-CoV-2 “infected-vaccinated” humans

Scientists were inspired by the robust serum nAb responses in people who recovered from natural SARS-CoV-2 infection and were later vaccinated using mRNA vaccine. They isolated and characterized bnAbs from two COVID-19 convalescent donors who were recently vaccinated. These isolated bnAbs were found to be highly potent against sarbecoviruses. This research is available on the bioRxiv* preprint server.

13 Sep 2021

Research suggests current smokers not at excess risk of SARS-CoV-2 infection

Now, a new study published on the bioRxiv* preprint server investigates this relationship further and suggests that current smoking is not associated with a higher incidence of SARS-CoV-2 infection.

13 Sep 2021

As COVID restrictions were removed, Texas saw an increase in seasonal respiratory virus infections

Like many US states, Texas introduced many different measures to reduce the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), such as masking, social distancing, and the closure of public services and businesses likely to aid the spread of disease.

13 Sep 2021

An investigation of SARS-CoV-2 infections among Australian passengers on the Diamond Princess cruise ship

The Diamond Princess Cruise ship left Yokohama (Japan) on 20 January 2020, for a fourteen-day tour with shore excursions in Japan, Hong Kong, Vietnam, and Taiwan. Unfortunately, one of the passengers who complained of mild dry cough was later confirmed to be SARS-CoV-2 positive. In due course, 19% of the passengers were infected with the virus, and thirteen people died.

13 Sep 2021

Acid pH enhances SARS-CoV-2 infection by up-regulating ACE2 receptor

A new study published in the journal Frontiers of Medicine indicated that Barrett's esophagus (BE) and gastroesophageal reflux disease (GERD) may represent novel comorbidities associated with SARS-CoV-2 disease. A previous study had estimated that in the United States, 5.6% of adults have BE, a disease where esophageal squamous mucosa gets damaged by GERD.

12 Sep 2021

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

A recent study, currently available on the bioRxiv* preprint server, reveals that a specific region of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be targeted by antisense oligonucleotides to potently inhibit viral replication, and consequently the development of coronavirus disease (COVID-19).

12 Sep 2021

Lessons from COVID-19 response during first three waves in New South Wales

Scientists from Australia have recently analyzed the public health measures adopted by the authorities during the three waves of coronavirus disease 2019 (COVID-19) pandemic in New South Wales, Australia.

12 Sep 2021

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

A recent report published in the journal Cell Discovery has described the immunogenicity and protective efficacy of a novel coronavirus disease 2019 (COVID-19) subunit vaccine candidate. The vaccine induces robust immune responses in rodents and non-human primates and protects the animals against severe disease.

12 Sep 2021

Researchers identify the spleen as primary site for priming of 'killer' T cells during influenza infection

CD8+ T cells - known as "killer" T cells - are the assassins of the immune system. Once they are primed, they seek out and destroy other cells that are infected with virus or cells that are cancerous.

12 Sep 2021

The strengths and weaknesses of the spike protein in SARS-CoV-2 variants

The S protein has the ability to appropriate various conformations that are dependent on the formation of the receptor-binding domain (RBD) of its protomers.

12 Sep 2021

Does Delta increase the risk of hospitalization compared with Alpha?

A team of researchers conducted a cohort study to understand the risk of hospitalization in patients with either the Delta or Alpha variants of SARS-CoV-2.

12 Sep 2021

Neoadjuvant CPA followed by surgical resection and maintenance atezolizumab meets safety criteria

Neoadjuvant cisplatin and pemetrexed plus atezolizumab followed by surgical resection and maintenance atezolizumab met safety criteria, according to research presented today in OA13: Topics in Pleural Mesothelioma at the IASLC 2021 World Conference on Lung Cancer.

12 Sep 2021

Respiratory News and Research

The comparative effectiveness of neutralizing monoclonal antibodies against SARS-CoV-2

An oral COVID-19 vaccine induces mucosal and protective immunity

The rate of vaccine-induced heart inflammation in children

Australia's response to COVID-19 pandemic

Low-dose CT lung cancer screening linked to reduction in lung cancer mortality

Discovery of diverse sarbecovirus broadly neutralizing antibodies from SARS-CoV-2 “infected-vaccinated” humans

Research suggests current smokers not at excess risk of SARS-CoV-2 infection

As COVID restrictions were removed, Texas saw an increase in seasonal respiratory virus infections

An investigation of SARS-CoV-2 infections among Australian passengers on the Diamond Princess cruise ship

Acid pH enhances SARS-CoV-2 infection by up-regulating ACE2 receptor

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

Lessons from COVID-19 response during first three waves in New South Wales

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

Researchers identify the spleen as primary site for priming of 'killer' T cells during influenza infection

The strengths and weaknesses of the spike protein in SARS-CoV-2 variants

Does Delta increase the risk of hospitalization compared with Alpha?

Neoadjuvant CPA followed by surgical resection and maintenance atezolizumab meets safety criteria

First rat model recapitulates all disabling alterations experienced by patients with Morquio A disease

UGA research offers hope for a viable therapeutic to combat COVID-19

Study: Canadians have the highest risk of respiratory mortality from wildfire pollution

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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