Therapeutics News and Research

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Unnatural DNA bases: an interview with Professor Floyd E. Romesberg, The Scripps Research Institute

The natural DNA bases that form the letters of DNA are usually referred to as G, C, A, and T. Those are only the first letters of the chemical names. They’re often called nucleotides by their scientific name and all of them have in common a phosphate part, a sugar part and a nucleobase part.

21 Jul 2014

CFDA approves CASI's ENMD-2076 Phase II trial in triple-negative breast cancer patients

CASI Pharmaceuticals, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and other diseases, announced today that China's Food and Drug Administration has approved the Company's application to conduct a Phase II clinical trial in triple-negative breast cancer (TNBC) patients in China for its proprietary drug candidate, ENMD-2076.

21 Jul 2014

Study reveals new invasion mechanism of Enterovirus 71

A new study determines glycosylation and pH-dependent conformational changes of virus receptor SCARB2 as crucial for EV71 attachment, entry and uncoating.

21 Jul 2014

Doctor maps path of discovery for developing potential anticancer agent

The journal Cancer Cell today published research led by Dr. Tak Mak mapping the path of discovery to developing a potential anticancer agent.

18 Jul 2014

Scientists find single gene that plays surprising role in manipulating aging

It is something of an eternal question: Can we slow or even reverse the aging process? Even though genetic manipulations can, in fact, alter some cellular dynamics, little is known about the mechanisms of the aging process in living organisms.

18 Jul 2014

Phase 2 dose-ranging study of AYX1 for prevention of post-surgical pain

Adynxx, developer of a first-in-class platform of therapeutics to address pain at its molecular roots, announced today that the first patient was dosed in ADYX-003, a Phase 2 dose-ranging study of AYX1, an investigational drug candidate for the prevention of post-surgical pain.

17 Jul 2014

Researchers discover how dengue suppresses human immune system

Scientists have discovered a new pathway the dengue virus takes to suppress the human immune system. This new knowledge deepens our understanding of the virus and could contribute to the development of more effective therapeutics.

17 Jul 2014

Researchers develop world's first T-cell peptide-based vaccine for heart disease

Researchers at Wayne State University have made a fundamental discovery and, in subsequent collaboration with scientists at La Jolla Institute for Allergy and Immunology (LIAI), are one step closer to the goal of developing the world's first T-cell peptide-based vaccine for heart disease - the number one killer in the nation.

17 Jul 2014

Research reveals structural differences of protein involved in Huntington's disease

Neutron scattering research at the Department of Energy's Oak Ridge National Laboratory has revealed clear structural differences in the normal and pathological forms of a protein involved in Huntington's disease.

17 Jul 2014

Scientist fights extremely aggressive and difficult-to-treat form of breast cancer

Biomedical scientist Kimberly L. Koss, PhD, is fighting an extremely aggressive and difficult-to-treat form of breast cancer.

17 Jul 2014

Advanced Cell Diagnostics’ in situ hybridization technology reaches two major milestones

Advanced Cell Diagnostics Inc. (ACD), a leader in the field of molecular pathology and developer of cell and tissue-based analysis tools, has announced that its RNAscope® RNA in situ hybridization technology has reached two major milestones. In just three years, over 100 peer-reviewed papers featuring the technology have been published, and with the significant increase in use of RNAscope, ACD has now built a library of over 4000 target probes for numerous species. Probes are designed to order in under two weeks, and in just six months the library has grown by over 1500, reflecting the wide interest in ACD’s breakthrough technology.

From Advanced Cell Diagnostics 15 Jul 2014

Study confirms Stretta therapy as safe, effective treatment for GERD

A newly published peer-reviewed paper concludes that Stretta therapy is a safe, effective and durable treatment for gastro esophageal reflux disease (GERD). The paper states that Stretta addresses a significant unmet need where patients receive inadequate control from PPI therapy and find surgery an undesirable option.

15 Jul 2014

Scientists show how cannabis could reduce tumor growth in cancer patients

Scientists at the University of East Anglia have shown how the main psychoactive ingredient in cannabis could reduce tumor growth in cancer patients.

15 Jul 2014

DARPins could revolutionize protein therapeutics

Integrating an INTEGRA VIAFLO 96 multichannel pipette into their high throughput expression facility has enabled Molecular Partners (Zurich, Switzerland) to streamline the discovery and development of a novel class of targeted protein therapeutics termed DARPins.

From INTEGRA Biosciences 15 Jul 2014

Therapeutics News and Research

Unnatural DNA bases: an interview with Professor Floyd E. Romesberg, The Scripps Research Institute

CFDA approves CASI's ENMD-2076 Phase II trial in triple-negative breast cancer patients

Study reveals new invasion mechanism of Enterovirus 71

Doctor maps path of discovery for developing potential anticancer agent

Scientists find single gene that plays surprising role in manipulating aging

Phase 2 dose-ranging study of AYX1 for prevention of post-surgical pain

Researchers discover how dengue suppresses human immune system

Researchers develop world's first T-cell peptide-based vaccine for heart disease

Research reveals structural differences of protein involved in Huntington's disease

Scientist fights extremely aggressive and difficult-to-treat form of breast cancer

Advanced Cell Diagnostics’ in situ hybridization technology reaches two major milestones

Study confirms Stretta therapy as safe, effective treatment for GERD

Scientists show how cannabis could reduce tumor growth in cancer patients

DARPins could revolutionize protein therapeutics

A*STAR, Roche partner to identify novel drug targets for cancer treatment

Pareto partners with DNA2.0 to develop technology for quick-to-market products

Baxter International acquires drug candidate developed to treat sickle cell disease

New pathway to disabling disease: blocking bacteria's access to iron in the body

New class of anti-arthritic drugs reduce arthritic joint inflammation and periodontitis

PTC Therapeutics initiates reimbursed expanded access program for Translarna

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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