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New drug can have a promising effect in cancer patients with active brain metastases

An international clinical study led by the Medical University of Vienna shows that the drug patritumab deruxtecan (HER3-DXd) can have a promising effect in patients with active brain metastases of various tumor types.

28 Oct 2025

Simple, low-cost interventions could help reduce heat stress for garment workers

Simple, low-cost interventions could help reduce heat stress for the millions of people who work in garment factories in Bangladesh, where extreme temperatures make conditions unbearable, according to Australian researchers.

27 Oct 2025

Study finds evidence for repurposing thiostrepton as an anti-rhabdomyosarcoma drug

Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.

27 Oct 2025

New database transforms evidence-based care for children with lower respiratory tract infections

Lower respiratory tract infections (LRTIs) remain the most common illnesses in children, accounting for up to two-thirds of pediatric outpatient and inpatient cases in China.

24 Oct 2025

Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions

A collaborative research group led by Haruna Kimura (graduate student), Dr. Akito Hasegawa (Assistant Professor), and Prof. Riichiro Abe from the Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, together with Prof. Takemasa Ozawa from the Department of Chemistry, School of Science, The University of Tokyo, and Dr. Yoichi Ogawa (Lecturer) from the Department of Dermatology, Faculty of Medicine, University of Yamanashi, has developed a novel therapeutic candidate that may improve the prognosis of severe cutaneous adverse reactions such as Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).

24 Oct 2025

Psilocybin and mindfulness offer new hope for depressive healthcare workers

Frontline healthcare workers struggling with depression after the COVID-19 pandemic experienced significant relief from a treatment combining psilocybin group therapy with mindfulness training, according to a new study from Huntsman Mental Health Institute at University of Utah Health.

23 Oct 2025

International experts publish guidelines on the administration of gene therapy for hereditary hearing loss

Up to 60% of congenital and early-onset hearing loss is caused by genetic mutations in an inherited gene, and gene therapy has recently emerged as a potential treatment option.

23 Oct 2025

Enamine contributes to the discovery of promising broad-spectrum coronavirus antiviral

Enamine, a leading chemistry and R&D services company, today announced that it was a key synthetic chemistry contributor to a first-of-its-kind, open-science approach that led to the development of a promising broad-spectrum coronavirus antiviral pre-clinical candidate.

23 Oct 2025

Can introducing peanuts early prevent allergies? Real-world data confirms it helps

Using data from over 120,000 U.S. children, this Pediatrics study found that the prevalence and risk of peanut and other IgE-mediated food allergies declined significantly after the 2015 and 2017 guidelines promoting early allergen introduction. The findings support these policies as effective public health measures to prevent food allergies in real-world settings.

22 Oct 2025

Scientists identify Bidara leaf extracts as the most effective natural antimicrobial source

Researchers tested methanolic extracts from the leaves, bark, roots, stems, and fruits of Ziziphus mauritiana (Bidara) and found the leaves had the strongest antibacterial and antifungal effects. The study highlights the plant’s antimicrobial potential while emphasizing the need for further bioactive compound identification and toxicity testing.

22 Oct 2025

AI-driven eye screening aims to close the diabetic vision gap in community clinics

A new trial will evaluate whether integrating autonomous AI screening for diabetic retinopathy into U.S. federally qualified health centers can boost screening completion and accelerate early detection. The DRES-POCAI protocol tests a real-world, point-of-care model that links FDA-cleared AI with electronic health records to close gaps in diabetes eye care.

22 Oct 2025

Repeated ketamine infusions offer no extra benefit for people hospitalized with depression

Findings from a randomized and blinded clinical trial investigating repeated ketamine infusions for treating depression have revealed no extra benefit for ketamine when added onto standard care for people admitted to hospital for depression.

22 Oct 2025

Scientists question the safety and efficacy of the diet for metabolic health

A study published in Science Advances by University of Utah Health researchers sheds light on the long-term effects of the ketogenic diet, raising important questions about its safety and efficacy for improving metabolic health.

22 Oct 2025

Discovery offers a breakthrough approach to combat prostate tumor growth

Prostate cancer relies on genetic "switches", called enhancers, that can turn on tumor-promoting genes.

22 Oct 2025

Epidural stimulation and physical rehabilitation can enhance recovery in spinal cord injury patients

Spinal cord injury (SCI) causes paralysis in roughly one million people worldwide, with incident cases rising yearly.

21 Oct 2025

Researchers develop a novel approach to monitor CD8⁺ T cell activity over time

The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key to the success of modern day cancer immunotherapies.

21 Oct 2025

Genetic inflammatory signature defines depression subtypes and treatment response

Researchers led by Prof. Alessandro Serretti at Kore University of Enna have identified a genetic inflammatory signature that defines specific depression subtypes and influences how patients respond to antidepressant medications, according to new peer-reviewed research published today in Genomic Psychiatry.

21 Oct 2025

Study provides a new approach for the treatment of prostate tumors

An international research team led by the Medical University of Vienna has demonstrated for the first time that thyroid hormone plays a key role in the development and progression of prostate cancer.

21 Oct 2025

Cyclana Bio raises £5M to advance drug discovery for endometriosis

Cyclana Bio, a biotechnology company pioneering tissue-level approaches to women's health, today announced the close of a £5M pre-seed funding round, co-led by NfX and Eka VC, and including Cocoa VC, Wilbe, and Angel investors.

21 Oct 2025

Novel combination therapy shows promise for advanced neuroendocrine tumors

A novel combination therapy pairing a DNA-synthesis inhibitor with a targeted radiopharmaceutical may improve outcomes for patients with advanced neuroendocrine tumors, according to new clinical trial data presented this week at the European Society for Medical Oncology (ESMO) Congress 2025.

21 Oct 2025

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Efficacy News and Research

New drug can have a promising effect in cancer patients with active brain metastases

Simple, low-cost interventions could help reduce heat stress for garment workers

Study finds evidence for repurposing thiostrepton as an anti-rhabdomyosarcoma drug

New database transforms evidence-based care for children with lower respiratory tract infections

Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions

Psilocybin and mindfulness offer new hope for depressive healthcare workers

International experts publish guidelines on the administration of gene therapy for hereditary hearing loss

Enamine contributes to the discovery of promising broad-spectrum coronavirus antiviral

Can introducing peanuts early prevent allergies? Real-world data confirms it helps

Scientists identify Bidara leaf extracts as the most effective natural antimicrobial source

AI-driven eye screening aims to close the diabetic vision gap in community clinics

Repeated ketamine infusions offer no extra benefit for people hospitalized with depression

Scientists question the safety and efficacy of the diet for metabolic health

Discovery offers a breakthrough approach to combat prostate tumor growth

Epidural stimulation and physical rehabilitation can enhance recovery in spinal cord injury patients

Researchers develop a novel approach to monitor CD8⁺ T cell activity over time

Genetic inflammatory signature defines depression subtypes and treatment response

Study provides a new approach for the treatment of prostate tumors

Cyclana Bio raises £5M to advance drug discovery for endometriosis

Novel combination therapy shows promise for advanced neuroendocrine tumors

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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