Cardiometabolic News and Research

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Plant-based quinoa burgers reduce post-meal blood sugar spikes

A study reveals that plant-based burgers with baru pulp and red quinoa trigger lower blood sugar spikes than glucose, highlighting their potential in nutrition.

10 Jun 2026

GLP-1 medicines may cut clot-related risks in chronically inflamed patients

In a target trial emulation using OneFlorida+ electronic health record data, GLP-1 receptor agonist use in adults with obesity and autoimmune disease was linked to lower hazards of pulmonary embolism, venous thromboembolism, stroke/TIA, emergency department visits, and all-cause mortality.

10 Jun 2026

Injectable semaglutide may improve fertility outcomes in PMOS

Researchers at the University of Colorado Anschutz have published a proof-of-concept study in Fertility and Sterility demonstrating that injectable semaglutide may offer meaningful reproductive benefits for women with polyendocrine metabolic ovarian syndrome (PMOS), formerly known as polycystic ovary syndrome (PCOS).

9 Jun 2026

Apitegromab helps tirzepatide users lose fat while preserving lean mass

A phase 2 trial found that apitegromab plus tirzepatide reduced lean body mass loss by 1.9 kg compared with tirzepatide plus placebo after 24 weeks, while overall weight loss remained similar.

9 Jun 2026

Obesity drug mazdutide reduces weight and waist size in major trial

Once-weekly 9 mg mazdutide produced clinically meaningful weight loss in Chinese adults with obesity, reducing body weight by 16.65% after 60 weeks versus 1.50% with placebo. The phase 3 GLORY-2 trial also found improvements in waist circumference, systolic blood pressure, and lipid markers, but gastrointestinal adverse events were common.

9 Jun 2026

Excess weight identified as key driver for cardiovascular-kidney-metabolic syndrome

The first-ever clinical guideline for cardiovascular-kidney-metabolic syndrome, or CKM syndrome, identifies excess weight, especially in the abdomen, as a key driver for the syndrome. T

9 Jun 2026

New clinical guidelines target interconnected heart, kidney and metabolic risks

The American Heart Association and the American College of Cardiology, along with two other leading medical organizations have developed the first-ever guideline aimed at preventing and managing cardiovascular-kidney-metabolic (CKM) syndrome, an interconnected set of health conditions that significantly increase the risk of multiorgan complications and negative cardiovascular outcomes.

9 Jun 2026

The best meal timing for blood sugar may be earlier dinners

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9 Jun 2026

Fathers shape childhood obesity risk long before birth

New research highlights fathers' influence on childhood obesity risk through sperm changes, lifestyle, and parenting, urging inclusive prevention strategies.

9 Jun 2026

GLP-1 therapies linked to fewer complications in adults with both obesity and autoimmune disease

Among adults with both obesity and an autoimmune disease, those taking a glucagon-like peptide-receptor 1 agonist (GLP-1RA) medication had lower rates of emergency department visits and were less likely to experience serious cardiac events, such as stroke, pulmonary embolism or death when compared to similar adults who were not taking these medications, according to new research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

7 Jun 2026

Can Pilates improve heart and metabolic health in a month?

Pilates enhances cardiovascular and metabolic health in previously sedentary women, with notable improvements in heart rate and blood pressure after 4 weeks.

5 Jun 2026

Industrial processing of food poses health risks beyond poor nutrition

Concerns about the health effects of ultra-processed foods are growing, as studies increasingly link them to conditions such as heart disease, diabetes, and even early death.

4 Jun 2026

Why exercise matters for obesity even when the scale barely moves

AHA's scientific statement reveals exercise's vital role in obesity management, boosting cardiovascular health and supporting long-term weight loss efforts.

4 Jun 2026

Exercise during pregnancy links to lower infant BMI at one year

Supervised exercise during pregnancy may lower infant BMI and reduce obesity risk, highlighting the impact of maternal health on early growth trajectories.

4 Jun 2026

Higher genetic pulse pressure risk associated with dementia-related mortality

When looking at genetic variants in a person's DNA that predispose them to disease, a new study has found having a higher number of genetic variants for increased pulse pressure is associated with a small, increased risk of dementia as a contributing cause of death.

3 Jun 2026

What pregnancy reveals about a woman’s future heart health

Pregnancy acts as a natural cardiovascular stress test, revealing hidden heart disease and identifying women at higher long-term risk after complications such as preeclampsia, gestational diabetes, and preterm birth. The review highlights major evidence gaps in cardio-obstetric care and calls for stronger postpartum screening, dedicated women’s health clinics, and better inclusion of reproductive-age women in research.

3 Jun 2026

Continuing gout therapy during remission lowers future flare risk

The European Alliance of Associations for Rheumatology - held its 2026 annual Congress in London, where gout was high on the agenda.

3 Jun 2026

Is any level of alcohol safe? Major review reveals where drinking risks rise

This Burden of Proof review found that alcohol consumption is associated with higher risks for several cancers, liver disease, pancreatitis, lower respiratory infections, tuberculosis, and atrial fibrillation. Although low-to-moderate drinking showed modest observational links with lower risks of type 2 diabetes, dementia, and some cardiovascular outcomes, the evidence was weaker and potentially biased.

2 Jun 2026

Physical activity protects heart health regardless of weight loss

With obesity now affecting more than 40% of U.S. adults and fueling rising rates of heart disease, a new scientific statement from the American Heart Association calls for a comprehensive treatment approach that puts physical activity front and center.

1 Jun 2026

How do everyday spices help protect the heart?

A Nutrition Reviews supplement article reviewed controlled studies showing that culinary spice and herb blends may improve selected cardiometabolic risk markers, including post-meal triglycerides, insulin responses, inflammation, endothelial function, and 24-hour blood pressure. The review also highlighted exploratory evidence that spices and herbs may influence immune-cell activity, circulating phytochemical metabolites, and gut bacterial composition, while emphasizing the need for longer and more diverse studies.

27 May 2026