Cell Signaling News and Research

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Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

GUK1 enzyme plays crucial role in lung cancer metabolism and growth

Lung cancer is a particularly challenging form of cancer. It often strikes unexpectedly and aggressively with little warning, and it can shapeshift in unpredictable ways to evade treatment.

10 Feb 2025

University of Oulu advances biosensor technology for disease detection

The University of Oulu is at the forefront of developing cutting-edge biosensor technology that could revolutionize the early diagnosis and treatment of diseases.

10 Feb 2025

Understanding the role of alternative splicing in cardiovascular diseases

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor RNA to produce multiple transcript variants.

8 Feb 2025

Collagen's structural diversity may be greater than previously believed, study suggests

Collagen, the body's most abundant protein, has long been viewed as a predictable structural component of tissues.

7 Feb 2025

New gene modification enhances CAR-T cell effectiveness against cancer

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying a specific gene improves the ability of immune cells to combat cancer for an extended period, potentially reducing the chance of cancer recurring.

7 Feb 2025

Bio-based "living" material with self-healing properties could revolutionize regenerative medicine

A biomaterial that can mimic certain behaviors within biological tissues could advance regenerative medicine, disease modeling, soft robotics and more, according to researchers at Penn State.

7 Feb 2025

Duke engineers develop AI platform to target undruggable disease proteins

Biomedical engineers at Duke University have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing proteins.

31 Jan 2025

Bioengineers create non-invasive way to control cells using temperature

Imagine being at a big marquee event at an arena, like the Super Bowl, with the roar of the crowd, the smell of hot dogs, and a sea of jerseys all merging into one chaotic blur.

29 Jan 2025

Establishing common nomenclature for mitochondria transfer and transplantation

Most animal, plant and fungal cells contain organelles called mitochondria. These descendants of a primordial bacterial endosymbiont still preserve distinct genes and are known for their ability to create ATP as chemical energy.

27 Jan 2025

Study reveals new mechanism behind gene expression regulation in animal cells

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem cells, and neural activation processes.

24 Jan 2025

Targeting tertiary lymphoid structures for cancer treatment

A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid structures (TLSs) in response to foreign threats such as cancer.

16 Jan 2025

Biglycan and decorin play crucial roles in bone health

Bone tissue is a complex structure, consisting of mineralized collagen fibers and a variety of non-collagenous proteins, including proteoglycans such as biglycan and decorin.

10 Jan 2025

Stress-induced immune dysfunction linked to worsened skin allergies

Psychological stress is known to exacerbate skin allergies, but the underlying molecular mechanisms remain poorly understood.

7 Jan 2025

Study unveils novel pathway triggering immune response to DNA damage

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged.

6 Jan 2025

SMART software offers new solution for modeling cell-signaling networks

Researchers at University of California San Diego have developed and tested a new software package, called Spatial Modeling Algorithms for Reactions and Transport (SMART), that can realistically simulate cell-signaling networks - the complex systems of molecular interactions that allow cells to respond to diverse cues from their environment.

19 Dec 2024

Lipid imbalances hold the key to chronic inflammation in colon cancer

Scientists uncover how disrupted lipid metabolism fuels chronic inflammation in colorectal cancer, offering insights into new therapeutic strategies targeting pro-inflammatory and pro-resolving lipid imbalances.

12 Dec 2024

Bacterial toxin may fuel colorectal cancer metastasis

A toxin in the bacteria that's one of the most common causes of foodborne illness accelerates the spread of colorectal tumors to other parts of the body, a study led by UF Health Cancer Center researchers and international collaborators has found.

6 Dec 2024

Study challenges long-standing understanding of axon structure

Biology textbooks may need a revision, say Johns Hopkins Medicine scientists, who present new evidence that an armlike structure of mammalian brain cells may be a different shape than scientists have assumed for more than a century.

2 Dec 2024

Study reveals protein mobility defect as a key factor in chronic diseases

Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically taxing, and the number of people with such diseases is growing.

27 Nov 2024

Memories of obesity can linger in fat cells long after weight loss

Epigenetic changes from obesity persist after weight loss, altering fat cell function and increasing the risk of weight regain, impacting metabolic health.

19 Nov 2024