Gerontology News and Research

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Gerontology is the study of the social, psychological and biological aspects of aging.

Mild cognitive impairment linked to decline in decision-making abilities

Mild cognitive impairment (MCI) is a form of cognitive ability loss that can precede Alzheimer's disease or other types of dementia.

16 Aug 2023

New Alzheimer’s drug raises hopes — along with questions

The FDA has approved Leqembi, the first disease-modifying treatment for early-stage Alzheimer's and a precursor condition, mild cognitive impairment.

11 Aug 2023

NLRP3 inflammasome plays a role in podocyte aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, "Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span."

8 Aug 2023

Moderna vaccine linked to lower risk of adverse events in older adults

While mRNA vaccines against COVID-19 have been found to be safe and effective for the general population, in-depth evidence about safety and effectiveness for older adults and individuals with chronic health conditions is more limited.

2 Aug 2023

Human senescent fibroblasts trigger fibrogenic reaction in the lungs of immunodeficient mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, "Human senescent fibroblasts trigger progressive lung fibrosis in mice."

31 Jul 2023

Penn Medicine researchers identify new therapeutic target for Alzheimer's disease

A gene encoding a protein linked to tau production-;tripartite motif protein 11 (TRIM11)-;was found to suppress deterioration in small animal models of neurodegenerative diseases similar to Alzheimer's disease (AD), while improving cognitive and motor abilities, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

27 Jul 2023

Nursing Work Index translations could help improve quality and safety of care worldwide

Two decades ago, the Practice Environment Scale of the Nursing Work Index was published to measure the nursing practice environment.

27 Jul 2023

Positive experiences can reverse cognitive decline in old age

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 13, entitled, "MSK1 is required for the beneficial synaptic and cognitive effects of enriched experience across the lifespan."

26 Jul 2023

Older sexual and gender minority adults have higher rates of frailty, study shows

In June, the U.S. Census Bureau announced that the average age of the U.S. population reached a new high of nearly 39 years old.

25 Jul 2023

BUB1 protein and its kinase activity may regulate EGFR activation

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 13, entitled, "Budding uninhibited by benzimidazoles-1 (BUB1) regulates EGFR signaling by reducing EGFR internalization."

18 Jul 2023

MemTrax continuous recognition test shows promise in early detection of Alzheimer's disease

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, "Advancing screening for cognitive impairment: the memtrax continuous recognition test."

13 Jul 2023

LSU Health New Orleans' School of Nursing receives HRSA grant to address health care workforce challenges

The Health Resources and Services Administration (HRSA) has awarded LSU Health New Orleans' School of Nursing $2.6 million over four years to increase the number of nurse practitioners and nurse midwives trained and prepared to provide equitable, culturally aligned, quality primary care services, mental health and substance use disorder care, and maternal health care to underrepresented populations in rural, urban, tribal, and underserved areas across the state.

13 Jul 2023

Researchers develop a chemical approach to reverse aging

In a groundbreaking study, researchers have unlocked a new frontier in the fight against aging and age-related diseases.

12 Jul 2023

Mouse model of Hutchinson-Gilford progeria syndrome shows reduction in hepatic H2S levels

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, "Hepatic hydrogen sulfide levels are reduced in mouse model of Hutchinson-Gilford progeria syndrome."

11 Jul 2023

New mouse model mimics the development of frailty in older adults

Researchers at the Johns Hopkins University School of Medicine have developed a mouse model that successfully mimics the development of frailty as mammals — likely including people — get older.

11 Jul 2023

Social isolation a risk factor for smoking in older adults

Aging brings wisdom and experience; however, for some individuals getting older can also mean health challenges, loss of friends, and decreased mobility, leading to social isolation.

6 Jul 2023

Novel peptide T14 levels may be an indicator of skin age and photo-aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, "A novel peptide 'T14' reflects age and photo-aging in human skin."

5 Jul 2023

Combining proteomic and miRNA data yields superior age predictions, study suggests

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, "Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis."

30 Jun 2023

Experts call for accelerated development of function-promoting therapies for older adults

Experts have identified a public health need as well as strategic opportunities for the accelerated development of function-promoting therapies for older adults -; and present new research on this topic in a supplemental issue of The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences inspired by a March 2022 workshop convened by the National Institute on Aging (NIA), part of the National Institutes of Health.

28 Jun 2023

Research shows the efficacy of methionine restriction to reverse old-age-induced obesity

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 11, entitled, "Old-age-induced obesity reversed by a methionine-deficient diet or oral administration of recombinant methioninase-producing Escherichia coli in C57BL/6 mice."

27 Jun 2023