Induced Pluripotent Stem Cells News and Research

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New technique boosts production of canine stem cells for veterinary use

Mesenchymal stem cells (MSCs), which can be harvested from fat and bone marrow, have immune-modulating and anti-inflammatory effects that are beneficial for both human and veterinary medicine.

20 Jun 2025

Chemical pairing of BPA and retinoic acid disrupts brain development

Synthetic chemicals and plastics are useful and indispensable in our lives. On the other hand, the world is grappling with plastic pollution-clogging oceans, threatening wildlife, and leaching into ecosystems.

19 Jun 2025

Fujifilm rebrands Life Sciences Companies to strengthen position as strategic partners for life, offering end-to-end solutions

FUJIFILM Corporation's Life Sciences Group companies, a portfolio of businesses offering products, services and comprehensive solutions that span all stages of therapeutic development from discovery through to commercialization, today announced new names and identities as part of a strategic positioning effort.

3 Jun 2025

Molecular psychiatrist redefines the genetic basis of neurodevelopmental conditions

In a comprehensive Genomic Press interview published today, Professor Barbara Franke unveils her remarkable scientific journey from an inquisitive child fascinated by nature to becoming one of the world's most influential researchers in biological psychiatry.

27 May 2025

Genetic variations in Prader-Willi syndrome offer key insights into autism and psychosis

In a comprehensive Genomic Press Invited Expert Review, researchers from the University of Haifa have synthesized cutting-edge findings on Prader-Willi syndrome (PWS), revealing how this complex neurodevelopmental disorder serves as a critical model for understanding the interplay between autism spectrum disorder (ASD) and psychotic spectrum disorders (PSD).

20 May 2025

MIT researchers discover new potential drug targets for Alzheimer’s disease

By combining information from many large datasets, MIT researchers have identified several new potential targets for treating or preventing Alzheimer's disease.

20 May 2025

Peptide nanostructures block amyloid buildup and boost neuron survival in lab tests

Researchers developed trehalose-functionalized peptide amphiphiles (TPAs) that self-assemble into supramolecular nanostructures and demonstrated these TPAs can inhibit amyloid beta aggregation. In vitro, TPAs significantly improved survival of human neurons exposed to amyloid-induced neurotoxicity, suggesting therapeutic potential for neurodegenerative diseases.

15 May 2025

New human ovaroid model offers insight into infertility and differences in sex development

A new model of tiny human ovary organoids, or ovaroids, has been developed from stem cells, according to research presented at the first Joint Congress between the European Society of Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE).

11 May 2025

St. Jude Children's scientists use brain organoids to study rare encephalopathy

While extremely rare, encephalopathy (a condition affecting brain function) triggered by mutations in the UBA5 gene has devastating impacts, with affected individuals reaching few developmental milestones and experiencing frequent and early-onset seizures.

8 May 2025

The Surgeon-Scientist Pioneering Regenerative Engineering

In this interview, Sir Prof. Cato T. Laurencin, the 2025 Coulter Lecturer, discusses how he is addressing today’s medical challenges using the technology of the future.

From Pittcon 5 May 2025

New gene editing tool enables precise control of mitochondrial mutation load

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes.

3 May 2025

Study links impaired synaptic pruning to autism

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition in which affected individuals experience difficulties in social communication and exhibit restricted, repetitive patterns of behavior or interests.

30 Apr 2025

Chimpanzee blastoids offer clues to early embryogenesis

Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology.

25 Apr 2025

Engineered brain cells offer new hope for treating Alzheimer's

A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to University of California, Irvine scientists.

21 Apr 2025

New discovery promises to revolutionize liver organoid development

Organoids are small-scale models that mimic human organs. These models could help scientists understand diseases and test treatments, and potentially aid in regenerative therapeutic methods.

8 Apr 2025

Study develops fused neural organoids with leptomeninges

A new study in the peer-reviewed journal Stem Cells and Development describes the development of a co-culture system of neural organoids generated from human induced pluripotent stem cells (iPSCs) fused with fetal leptomeninges from mice with fluorescently labeled meninges, called leptomeningeal neural organoid (LMNO) fusions.

26 Mar 2025

Genetic and environmental factors in schizophrenia

Schizophrenia affects millions worldwide, yet its causes remain one of the greatest medical mysteries. In an exclusive Genomic Press Interview, Dr. Consuelo Walss-Bass, a pioneering researcher in psychiatric genetics, shares how both genetic predisposition and environmental factors contribute to severe mental health disorders.

26 Mar 2025