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CIPHER-seq technology reveals how immune cells communicate during treatment

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic intent but real-time activity.

8 Apr 2026

Xuebijing injection reduces inflammation and ferroptosis in acute lung injury

Using an LPS-induced ALI mouse model and LPS-stimulated alveolar macrophages, they found XBJ reduced inflammatory cytokine surges, preserved alveolar barrier integrity, and limited tissue injury, while probing the molecular pathways and intracellular targets underlying these benefits.

7 Apr 2026

New ruthenium-based active agent enables cancer treatment in oxygen-depleted tumors

Most tumors grow so rapidly that vascular growth cannot keep up, and oxygen-depleted areas form within them. A new active agent could make it possible to treat them with photodynamic therapy.

7 Apr 2026

Deep UV microscopy enables label-free T cell characterization

A team of researchers at the Georgia Institute of Technology and Emory University has developed a deep-ultraviolet (UV) microscopy method that can rapidly assess T cell viability, activation state, and subtype-all without the need for fluorescent labels or cell destruction.

3 Apr 2026

Nanotube membrane injector enables precise transfer of cytoplasmic contents between cells

Cells are not isolated units; they continuously exchange proteins, genetic material, and even entire organelles with their neighbors.

3 Apr 2026

Tumor microenvironment drives resistance to ferroptosis in pancreatic cancer

Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can be harnessed for cancer therapy.

2 Apr 2026

Where digital holographic microscopy complements fluorescence microscopy

Integrating Digital Holographic Microscopy with fluorescence techniques enhances live-cell imaging, preserving cellular integrity and improving assay accuracy.

From Park Systems 2 Apr 2026

DNASE1L2 identified as a dynamic biomarker for TB progression

Tuberculosis (TB) remains one of the world's most serious public health threats, with approximately one-quarter of the global population infected with Mycobacterium tuberculosis. While most infections remain latent (LTBI), individuals with LTBI are at risk of progressing to active TB and potentially becoming new sources of transmission.

31 Mar 2026

Parasites trigger a gut-to-brain signal that cuts food intake during infection

Researchers found that intestinal tuft cells signal to crypt enterochromaffin cells by releasing acetylcholine, triggering serotonin release and activating a gut-to-brain vagal pathway during type 2 inflammation. This sustained signalling, rather than the initial acute response, was linked to reduced food intake in mouse models of parasitic infection.

29 Mar 2026

Immune cells use neurotransmitters to regulate health and disease

The article, titled "Emerging roles of immune cell-derived neurotransmitters in immunity and disease," published on March 17, 2026, in Immunity & Inflammation, provides a timely and authoritative review of how innate and adaptive immune cells-including macrophages, dendritic cells, natural killer cells, T cells, and B cells-produce and respond to classic neurotransmitters.

25 Mar 2026

SonoPIN technology boosts intracellular delivery of large cancer drugs

Engineers at Duke University have demonstrated a technique that uses microbubbles and ultrasound to help relatively large cancer drugs enter tumor cells and cause them to self-destruct.

13 Mar 2026

Pen-strep treatment rewires mechanical sensing in immune cells

Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to their phenotypic polarization and immune function.

13 Mar 2026

Researchers discover protein that promotes natural dental pulp tissue regeneration

Dental pulp injury caused by trauma or deep caries often leads to inflammation, tissue necrosis, and eventual loss of tooth vitality.

10 Mar 2026

Mapping the evolution of AI in organelle segmentation

In organelle imaging, segmentation aims to accurately delineate pixels or voxels corresponding to target organelles from background, noise, and other cellular structures in microscopy images, thereby generating masks suitable for quantitative analysis. Robust segmentation is foundational to downstream quantification, including morphological characterization, spatial distribution analysis, temporal trajectory tracking, and the detection of key biological events.

10 Mar 2026

Using engineered bacteria to breach tumor defenses

Baylor University researchers have published a novel approach to fight colorectal cancer, using modified bacteria as a courier to deliver potent cancer-killing proteins into tumor cells. Michael S. VanNieuwenhze, Ph.D., FRSC, University Distinguished Professor and chair of the Department of Biology, along with Baylor doctoral students and a colleague at Texas Tech University Health Sciences Center, published their promising research in Cell Chemical Biology.

10 Mar 2026

Protein aggregates in the liver may protect against alcohol-induced damage

Alcohol-associated liver disease (ALD) remains a leading cause of cirrhosis and liver-related mortality worldwide, with few effective therapies.

9 Mar 2026

Targeting Wnt signaling to solve the dental pulp challenge

Dental pulp regeneration remains a major clinical challenge. Researchers have discovered that SMAD7 directly forms a transcriptional complex with β-catenin in human dental pulp stem cells, activating Wnt signaling and promoting regenerative gene expression.

9 Mar 2026

Innovative peptide stapling system targets hard-to-treat cancers

Researchers at the University of Bath have developed a new technology that uses bacteria to build, chemically stabilize, and test millions of potential drug molecules inside living cells, making it much quicker and easier to discover new treatments for difficult-to-treat cancers.

3 Mar 2026

How zinc deficiency could worsen heart inflammation and what that means for patients

This review examines how zinc regulates inflammatory and redox signaling pathways involved in myocarditis and pericarditis, highlighting mechanisms such as NF-κB inhibition and the redox zinc switch. The authors conclude that maintaining optimal zinc status may support cardiovascular resilience, while emphasizing that clinical translation requires further targeted trials.

1 Mar 2026

Fe₃O₄@mPEG-Ag nanoparticles offer non-antibiotic strategy to combat drug-resistant bacteria

A collaborative study by Guangzhou Medical University and South China University of Technology, published in BME Frontiers, introduces Fe₃O₄@mPEG-Ag nanoparticles (NPs) as a groundbreaking non-antibiotic strategy to combat drug-resistant bacteria.

27 Feb 2026