Kidney Failure News and Research

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Study shows sharp increase in kidney disease deaths linked to high blood pressure

The death rate from hypertensive kidney disease (high blood pressure-related kidney disease) increased by 48% in the U.S. over the past 25 years, with continued differences across demographic groups, according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2025.

5 Sep 2025

First FDA-approved islet transplant at UI Health ends insulin dependence

Doctors at UI Health performed the first islet transplant with Lantidra, the only therapy approved by the U.S. Food and Drug Administration to treat brittle type 1 diabetes.

4 Sep 2025

Estrogen supports kidney regeneration and protects women from chronic disease

A new study in mice provides insights into why females in their reproductive years appear to be relatively protected from chronic kidney disease, a leading public health concern.

4 Sep 2025

Select groups of myocardial infarction patients benefit from Helicobacter pylori screening

Not all acute myocardial infarction patients should be offered routine screening for the stomach ulcer bacterium Helicobacter pylori.

1 Sep 2025

Lubiprostone shows promise in slowing kidney disease progression

Chronic kidney disease (CKD) is a major health issue worldwide. Many patients end up requiring regular dialysis to avoid kidney failure and stay alive.

1 Sep 2025

Constipation drug found to slow renal function decline in CKD patients

Chronic kidney disease (CKD) is a major health issue worldwide. Many patients end up requiring regular dialysis to avoid kidney failure and stay alive.

29 Aug 2025

Small peptide produced by gut bacteria identified as key factor in kidney fibrosis

A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis - a serious complication of diabetes and a leading cause of kidney failure - according to a new study from researchers at the University of Illinois Urbana-Champaign and Mie University in Japan.

25 Aug 2025

Trial finds no cardiovascular benefit and higher safety risks with spironolactone in dialysis patients

A large international study has found that spironolactone, a medication for high blood pressure and heart failure, does not reduce the risk of heart-related death or hospitalizations in people with kidney failure receiving dialysis, despite earlier smaller studies suggesting benefit.

17 Aug 2025

Study identifies biomarkers that could help predict and manage chronic kidney disease

Biomarkers that could help predict and manage chronic kidney disease (CKD) have been identified in a new study led by the University of Surrey.

12 Aug 2025

Early treatment withdrawal offers safety and savings for patients with rare kidney disease

Early withdrawal of a treatment for patients with a rare kidney disease is possible without relapse, safer for patients and saves the NHS millions of pounds, new research has revealed.

7 Aug 2025

Suppression of cdc42 activity could be a promising therapy for nephrotic syndrome

A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University revealed that elevated activity of cdc42 is a critical initiation event leading to proteinuria, and proposed that suppression of cdc42 activity could be a promising therapy for nephrotic syndrome.

6 Aug 2025

New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025

New Swiss study probes lingering fatigue after Legionnaires' disease

Researchers in Switzerland launched the LongLEGIO study to compare the long-term health impacts of Legionnaires’ disease and other bacterial pneumonias. Baseline data reveal key differences in comorbidities and quality of life between the groups, with follow-up underway.

4 Aug 2025

Addressing avoidable hospitalizations in terminally ill nursing home residents

Hospitalizations and emergency department (ED) visits can be distressing and costly for nursing home residents – especially those who are severely impaired or terminally ill. Despite their vulnerability, these individuals are frequently transferred to hospitals, even though up to 40% of such transfers over the past 25 years are considered potentially avoidable by health care professionals.

25 Jul 2025

AI tool helps doctors predict hospital death risk in cirrhosis patients

Predicting who might die while in the hospital is one of the hardest challenges for doctors caring for people with serious liver disease.

24 Jul 2025

Can one drug do it all? Reviewing the expanding clinical universe of GLP-1 agonists

Landmark trials have shown that GLP-1 receptor agonists, originally developed for diabetes and weight loss, also provide significant benefits for cardiovascular, kidney, liver, joint, and sleep-related diseases. These effects extend beyond weight loss, suggesting anti-inflammatory mechanisms with broad potential for managing chronic diseases.

22 Jul 2025

Maybe it’s not just aging. Maybe it’s anemia.

Gary Sergott felt weary all the time. "I'd get tired, short of breath, a sort of malaise," he said. He was cold even on warm days and looked pale with dark circles under his eyes.

17 Jul 2025

New analysis reveals widespread progression of CKM syndrome across the U.S.

One in three adults in the U.S. has three or more risk factors for a newly recognized but increasingly common condition: cardiovascular-kidney-metabolic (CKM) syndrome.

11 Jul 2025

Looking for a natural way to lower blood pressure? Whole grains might be the answer

A new meta-analysis of prospective cohort studies found that higher whole grain intake is linked to a significantly lower risk of developing hypertension, with a 26% risk reduction observed between highest and lowest intake groups. In contrast, refined grain consumption showed no clear association with hypertension risk.

2 Jul 2025

Study reveals persistent inequalities in children's access to kidney transplants across the UK

New research, presented at the ESOT Congress 2025, reveals persistent inequalities in children's access to life-saving kidney transplants across the UK.

1 Jul 2025