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COVID Moonshot Consortium makes major breakthrough in antiviral drug discovery

The work of the COVID Moonshot Consortium is being published in the prestigious journal Science on 10 November, revealing their discovery of a potent SARS-CoV-2 antiviral lead compound.

9 Nov 2023

Time-lapsed images show how magnesium ions coordinate double-stranded breaks in CRISPR-Cas9

The gene-editing technology known as CRISPR has led to revolutionary changes in agriculture, health research and more.

2 Nov 2023

New "clickable" pseudoviruses could revolutionize virus research

Pseudoviruses resemble impostors: although harmless, they are designed in such a way that they can hardly be distinguished from their dangerous relatives. This makes them an invaluable tool in virus research.

2 Nov 2023

UTA biology professor awarded NIH grant for new super-resolution microscope

UTA will soon add a new piece of cutting-edge equipment to its already impressive and growing research armamentarium-;a type of super-resolution microscope (SRM) that allows biologists to see structures within a cell in even finer detail.

31 Oct 2023

UTA bioengineer receives NIH grant to develop high-resolution imaging system to quantify cell tracking

The ability to dynamically track the movement of cells is essential for modeling cellular interactions as they form organs such as the heart. But current microscope technology isn't up to the task of capturing those movements.

30 Oct 2023

New course of treatment with existing drugs for cervical cancer reduces risk of death by 35%

A course of treatment with existing drugs prior to chemoradiation led to a 35% reduction in the risk of death or return of cancer, in trial results presented by researchers from UCL and UCLH.

25 Oct 2023

Researchers develop artificial intelligence tool for automatic colorectal cancer tissue analysis

Researchers from the University of Jyväskylä in collaboration with the Institute of Biomedicine University of Turku and Nova Central Finland have developed an artificial intelligence tool for automatic colorectal cancer tissue analysis.

24 Oct 2023

Neoadjuvant pembrolizumab achieves major pathologic response in more than half of patients with resectable melanoma

In exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major pathologic response in more than half of surgical specimens taken from patients who had been treated with neoadjuvant (pre-operative) pembrolizumab.

24 Oct 2023

Short course of induction chemotherapy can reduce cervical cancer relapse and death by 35%

The INTERLACE phase III trial, funded by Cancer Research UK and UCL Cancer Trials Centre, assessed whether a short course of induction chemotherapy (IC) prior to chemoradiation (CRT) could reduce the rate of relapse and death among patients with locally advanced cervical cancer.

22 Oct 2023

Researchers study how cells adapt to stressful and complex environments

Imagine the life of a yeast cell, floating around the kitchen in a spore that eventually lands on a bowl of grapes. Life is good: food for days, at least until someone notices the rotting fruit and throws them out.

16 Oct 2023

Researchers create a comprehensive cellular atlas of the Broca’s area in the brain

The brain is made up of numerous types of cells that are organized into different structures and regions.

12 Oct 2023

Ensuring raw material quality in drug production and manufacturing

In this interview, Thermo Fisher Scientific discusses how to ensure the high quality of raw material in the drug production and manufacturing pipeline.

From Thermo Fisher Scientific – Materials & Structural Analysis 12 Oct 2023

Accelerating drug discovery with analytical R&D solutions

In this interview, Thermo Fisher Scientific discusses how to accelerate drug discovery through analytical R&D.

From Thermo Fisher Scientific – Materials & Structural Analysis 12 Oct 2023

Decoding the twist: Coronavirus spike proteins reveal their intricate invasion dance

Researchers use cryo-EM and molecular dynamics to reveal conformational changes in the spike proteins of human coronavirus HKU1 upon binding with a receptor. Findings unveil the complexity of beta coronavirus attachment, suggesting a more intricate mechanism of host cell invasion than previously understood.

8 Oct 2023

Researchers create interpretable neural network to predict complex biological outcomes

A team of New York University computer scientists has created a neural network that can explain how it reaches its predictions.

6 Oct 2023

Study reveals unexpected variation in genetic code of protist

Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics.

6 Oct 2023

Parkinson's disease-related neuronal death more likely to occur at night

Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease.

29 Sep 2023

Neoadjuvant immunotherapy shows promise in multiple cancer types

Treating cancer with immunotherapies known as an immune checkpoint blockade (ICB) prior to surgery (so-called neoadjuvant immunotherapy) has been a rapidly growing area of research, but the scientific community is just scratching the surface of what is possible, according to a review article co-authored by several current and former investigators from the Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Kimmel Cancer Center.

28 Sep 2023

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

In some patients, infection with the pandemic virus SARS-CoV-2 can trigger a dangerous immune response in hardened fatty deposits (plaques) lining the heart's largest blood vessels, a new study shows.