Morphology News and Research

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What happens when microplastics reach the testes? Study shows autophagy and cell loss

Researchers found that microplastics from everyday plastic tableware accumulate in human semen and, although not linked to semen quality in the full cohort, were associated with altered sperm parameters in specific subgroups. Experimental models confirmed that 50 nm polystyrene particles trigger autophagy and apoptosis via the FOXA1/MAP3K1/p38 pathway, impairing sperm structure and function.

15 Oct 2025

Lifestyle choices and hormonal imbalances can impact men's reproductive health

A new research paper was published in Volume 12 of Oncoscience on September 30, 2025, titled "Lifestyle and hormonal factors affecting semen quality and sperm DNA integrity: A cross-sectional study."

10 Oct 2025

Tissue-mimicking hydrogels drive cell reprogramming via matrix remodeling

The mechanical properties of tissue matrix are crucial for maintaining cell health and function. With aging, tissue matrix loses its mechanical integrity and exhibits altered biophysical properties, which are closely associated with various diseases including neurodegenerative diseases and cancers.

30 Sep 2025

High-resolution imaging reveals how polymyxins trigger rapid shedding of bacterial armor

A team led by UCL (University College London) and Imperial College London researchers has shown for the first time how life-saving antibiotics called polymyxins pierce the armor of harmful bacteria.

30 Sep 2025

Researchers develop tool to predict how patients will respond to common multiple sclerosis drug

Brazilian researchers, in partnership with French institutions, have developed a tool that can predict how patients will respond to natalizumab, one of the most commonly used drugs for treating multiple sclerosis.

25 Sep 2025

Organophosphate pesticide exposure linked to reduced sperm quality in healthy men

This pilot study found that urinary metabolites of organophosphate pesticides were linked to reduced sperm motility in healthy young men, though results were preliminary. Oxidative stress did not explain the association, suggesting other biological pathways may be involved.

25 Sep 2025

How many cities will face unlivable heat by 2100?

Researchers assessed future urban heat exposure and adaptive capacity in 1,563 major cities worldwide, using high-resolution climate projections, local climate zones, and socioeconomic indicators. By 2100, hundreds of millions may live in cities exceeding habitability thresholds, with adaptation gaps greatest in low-income regions.

24 Sep 2025

New AI model predicts surgical complications more accurately than current scores

A new artificial intelligence model found previously undetected signals in routine heart tests that strongly predict which patients will suffer potentially deadly complications after surgery.

17 Sep 2025

How processed red meat might drive neurodegenerative diseases

The relationship between processed red meat and neurodegenerative diseases is complex, with potential risks and protective effects requiring more investigation.

15 Sep 2025

Green tea extract reduces weight and improves glucose control in obese mice

Green tea is an ancient beverage recognized for its medicinal and antioxidant properties. It has been widely studied for its beneficial effects on metabolic diseases, such as obesity and type 2 diabetes.

10 Sep 2025

Can cannabis use disrupt women’s fertility? New study finds strong evidence

Researchers found that THC, the psychoactive compound in cannabis, alters oocyte gene expression, spindle formation, and chromosome segregation, lowering embryo euploidy rates in IVF. This provides direct human evidence linking cannabis exposure to impaired female fertility outcomes.

10 Sep 2025

Key proteins found to shape sperm function and male fertility

There are many potential causes of infertility, and it can be challenging to pin down just what the problem is when a couple is having trouble getting pregnant.

10 Sep 2025

Stress in early life alters brain cell structure and behavior in mice

Canadian researchers show that stress modifies the morphology of brain cells in mice, directly influencing the rodents' level of physical activity.

4 Sep 2025

AI model detects genetic changes in colorectal cancer from tissue images

An international, interdisciplinary research team led by Prof. Jakob N. Kather from the Else Kröner Fresenius Center (EKFZ) for Digital Health at TUD Dresden University of Technology analyzed seven independent patient cohorts from Europe and the USA using their newly developed AI model.

20 Aug 2025

AI voice test could help spot dangerous throat lesions before symptoms appear

Researchers at Oregon Health and Science University found that variability in the harmonic-to-noise ratio (HNR) of speech could help distinguish benign from malignant vocal fold lesions, offering a potential early detection biomarker. The exploratory study used AI to analyze acoustic features from the Bridge2AI-Voice dataset and found differences most pronounced in male participants.

14 Aug 2025

Curcumin activates SIRT3 to protect bone structure in diabetic mice

In a new Scientific Reports study, curcumin protected bone-forming cells from high-glucose damage by activating the SIRT3/FoxO3a/NRF2 antioxidant pathway and restoring mitochondrial health. In diabetic mice, curcumin improved bone density and oxidative balance, highlighting its potential in osteoporosis prevention.

13 Aug 2025

New mouse model reveals key role of osteocytes in osteogenesis imperfecta

Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to be abnormal, leading to an increased risk of fractures.

13 Aug 2025

Special von Economo neurons may hold key to super-sharp memory in 80+ superagers

Researchers at Northwestern University’s SuperAging Program reveal how some people over 80 retain memory performance like those decades younger, linking it to unique brain structures, reduced pathology, and lower inflammation. Their 25-year study highlights genetic, cellular, and social traits that may protect cognitive function.

10 Aug 2025

AI-powered sweat sensor predicts anxiety before symptoms appear

Researchers have developed Stressomic, a wearable microfluidic biosensor that sequentially measures cortisol, epinephrine, and norepinephrine in sweat at six-minute intervals. The device distinguishes physical from psychological stress and predicts anxiety levels using machine learning.

7 Aug 2025

Breakthrough in nanoparticle technology could expand access to biologic medicines

In a discovery that could broaden access to next-generation biologic medicines and vaccines, researchers at the University of Chicago Pritzker School of Molecular Engineering (UChicago PME) have engineered polymer-based nanoparticles that form with a simple temperature shift-no harsh chemicals, no specialized equipment, and no processing needed.

7 Aug 2025

Morphology News and Research

What happens when microplastics reach the testes? Study shows autophagy and cell loss

Lifestyle choices and hormonal imbalances can impact men's reproductive health

Tissue-mimicking hydrogels drive cell reprogramming via matrix remodeling

High-resolution imaging reveals how polymyxins trigger rapid shedding of bacterial armor

Researchers develop tool to predict how patients will respond to common multiple sclerosis drug

Organophosphate pesticide exposure linked to reduced sperm quality in healthy men

How many cities will face unlivable heat by 2100?

New AI model predicts surgical complications more accurately than current scores

How processed red meat might drive neurodegenerative diseases

Green tea extract reduces weight and improves glucose control in obese mice

Can cannabis use disrupt women’s fertility? New study finds strong evidence

Key proteins found to shape sperm function and male fertility

Stress in early life alters brain cell structure and behavior in mice

AI model detects genetic changes in colorectal cancer from tissue images

AI voice test could help spot dangerous throat lesions before symptoms appear

Curcumin activates SIRT3 to protect bone structure in diabetic mice

New mouse model reveals key role of osteocytes in osteogenesis imperfecta

Special von Economo neurons may hold key to super-sharp memory in 80+ superagers

AI-powered sweat sensor predicts anxiety before symptoms appear

Breakthrough in nanoparticle technology could expand access to biologic medicines

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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