Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

The role of the fungal mycobiome in women's health

Researchers discuss the association between human mycobiota and female health.

15 Mar 2023

Study demonstrates long-term safety and clinical benefit of combination therapy for cystic fibrosis

Patients with cystic fibrosis (CF) face difficulty breathing and a decline in lung function and are at risk of early death. CF is an inherited condition that results in thick mucus build-up, persistent infection and inflammation in the lungs.

15 Mar 2023

Research identifies western diet-induced microbial and metabolic contributors to liver disease

New research from the University of Missouri School of Medicine has established a link between western diets high in fat and sugar and the development of non-alcoholic fatty liver disease, the leading cause of chronic liver disease.

15 Mar 2023

An emerging target for chronic kidney disease treatment - DNA-PKcs

A recent Nature Communications study suggested that DNA-PKcs could be a potential target for treating chronic kidney disease.

15 Mar 2023

Black lung resurgence drives push to protect coal miners against silica dust

Like most coal miners' loved ones, Liz Williams has endured many days and nights of worry.

14 Mar 2023

What are the risk factors associated with post-acute SARS-CoV-2 infection?

In a recent study posted to the Research Square* preprint server, researchers assessed the risk factors and predictive models for post-acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

13 Mar 2023

A review on two novel eating disorders

Researchers review existing data on avoidant/restrictive food intake disorder (ARFID) and atypical-type anorexia nervosa (AN).

13 Mar 2023

Study: Black patients with pulmonary fibrosis are younger than Hispanic and white counterparts

Pulmonary fibrosis is a devastating disease characterized by progressive scarring in the lungs, killing up to half of patients within five years of a diagnosis.

10 Mar 2023

ACE2: its diverse functions, relationship with SARS-CoV-2, and the implications for COVID-19 disease sequelae

Researchers assessed the role of ACE2 in the COVID-19 pandemic.

9 Mar 2023

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Researchers elucidated immunologic and genetic perturbations in long COVID patients with pulmonary fibrosis.

3 Mar 2023

Studying gut bacteria's role in muscle regeneration and recover

In a surprising discovery, Harvard Medical School researchers have found that a class of regulatory T cells (Tregs) made in the gut play a role in repairing injured muscles and mending damaged livers.

2 Mar 2023

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

The study findings demonstrate the power of spatial single-cell transcriptomics in studying COVID-19 lung pathology and other health and disease conditions.

1 Mar 2023

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

In a recent study published in Cells, researchers evaluated idiopathic pulmonary fibrosis (IPF) pathophysiological differences by sex and intestinal microbiome.

1 Mar 2023

New clinician toolkit aims to close the gaps in diagnosis of interstitial lung diseases

The expert steering committee for Bridging Specialties: Timely Diagnosis for ILD is encouraging primary care and pulmonary clinicians to come together on Rare Disease Day (February 28) to explore ways to shorten the time to diagnosis for pulmonary fibrosis and other interstitial lung diseases.

28 Feb 2023

Using sweat to diagnosis disease: soft microfluidic analysis systems assess health status

Researchers explored microfluidic systems with a skin interface in assessing chemical exposure and health status.

27 Feb 2023

Pathogenicity of SARS-CoV-2 viral components on human periodontal tissues and cells

Researchers assessed the impact of COVID-19 on fibrotic pathogenesis via the deregulation of mitochondrial beta-oxidation.

23 Feb 2023

UCI-led study uncovers how APOBEC3B protein could protect cells against RNA viruses

A new University of California, Irvine-led study uncovers how a protein, APOBEC3B, could protect cells against many different types of RNA viruses like respiratory syncytial virus (RSV), SARS-CoV2, influenza virus, poliovirus and measles, helping to prevent disease.

22 Feb 2023

The impact of specific comorbidities and overall multimorbidity on the three mechanistically distinct phases of COVID-19

Researchers studied the impact of comorbidities in the three distinct phases of COVID-19.

21 Feb 2023

Genome editing prevents hypertrophic cardiomyopathy in mice

In a recent study published in the journal PLoS Digital Health, researchers pursued one-time cures for hypertrophic cardiomyopathy (HCM). They used a previously constructed murine model of HCM, designated as R403Q-129SvEv, to evaluate two different genetic therapies, as follows:

19 Feb 2023

Canagliflozin ameliorates heart function in HFpEF rats partly by regulating ferroptosis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Sodium-glucose cotransporter-2 (SGLT2) inhibitors have been found to ameliorate major adverse cardiovascular events in patients with heart failure with preserved ejection fraction (HFpEF), but the exact mechanism is unknown.

17 Feb 2023

Fibrosis News and Research

Further Reading

The role of the fungal mycobiome in women's health

Study demonstrates long-term safety and clinical benefit of combination therapy for cystic fibrosis

Research identifies western diet-induced microbial and metabolic contributors to liver disease

An emerging target for chronic kidney disease treatment - DNA-PKcs

Black lung resurgence drives push to protect coal miners against silica dust

What are the risk factors associated with post-acute SARS-CoV-2 infection?

A review on two novel eating disorders

Study: Black patients with pulmonary fibrosis are younger than Hispanic and white counterparts

ACE2: its diverse functions, relationship with SARS-CoV-2, and the implications for COVID-19 disease sequelae

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Studying gut bacteria's role in muscle regeneration and recover

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

New clinician toolkit aims to close the gaps in diagnosis of interstitial lung diseases

Using sweat to diagnosis disease: soft microfluidic analysis systems assess health status

Pathogenicity of SARS-CoV-2 viral components on human periodontal tissues and cells

UCI-led study uncovers how APOBEC3B protein could protect cells against RNA viruses

The impact of specific comorbidities and overall multimorbidity on the three mechanistically distinct phases of COVID-19

Genome editing prevents hypertrophic cardiomyopathy in mice

Canagliflozin ameliorates heart function in HFpEF rats partly by regulating ferroptosis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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