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Research sheds light on Salmonella’s ability to escape gut defenses

A new UC Davis Health study has uncovered how Salmonella bacteria, a major cause of food poisoning, can invade the gut even when protective bacteria are present.

15 Nov 2024

TB pathogen's surprising growth mechanism challenges bacterial biology

The rod-shaped tuberculosis (TB) bacterium, which the World Health Organization has once again ranked as the top infectious disease killer globally, is the first single-celled organism ever observed to maintain a consistent growth rate throughout its life cycle.

15 Nov 2024

MEMPHIS system sheds light on vaccine response differences across ages

mRNA vaccines saved lives during the COVID-19 pandemic, but older people had less of an immune response to the vaccines than did younger adults. Why? Boston Children's researchers, led by Byron Brook, PhD, and Ofer Levy, MD, PhD, have found some answers, while providing proof-of-concept of a new system that can model vaccine responses in a dish.

15 Nov 2024

Excessive sedentary time linked to higher heart disease risk

More time spent sitting, reclining or lying down during the day may increase the risk of cardiovascular disease (CVD) and death, according to a study in JACC, the flagship journal of the American College of Cardiology, and presented at the American Heart Association's Scientific Sessions 2024.

15 Nov 2024

NYU Langone Health continues streak of "A" safety rating from Leapfrog

NYU Langone Health remains at the forefront of patient safety, with all of its inpatient locations earning "A" ratings from The Leapfrog Group, a national nonprofit watchdog organization focused on healthcare safety and quality.

15 Nov 2024

Gut microbiome found to play key role in chronic disease progression

The gut microbiome, an ecosystem of trillions of microorganisms in the human digestive tract, has been increasingly linked to chronic diseases.

15 Nov 2024

Comprehensive database reveals protein changes associated with aging

With the worldwide population aging at an unprecedented rate, the prevention of age-related diseases has become a prominent issue.

15 Nov 2024

Increased physical activity could add 5 years to American lifespan

If every American over the age of 40 was as physically active as the top 25% of the population, they could expect to live an extra 5 years, on average, suggest the findings of a modelling study published online in the British Journal of Sports Medicine.

15 Nov 2024

Obesity crisis in the U.S. expected to worsen by 2050

Over the past three decades, there has been a startling increase in the prevalence of obesity across the USA, at least doubling in adult men and women (aged 25 and older) and older female and male adolescents (aged 15-24 years) since 1990, with the number of people living with overweight and obesity reaching over 208 million in 2021 - a trend set to continue in the coming decades without significant reform, according to a major new analysis from the Global Burden of Disease Study Collaborator Network, published in The Lancet.

15 Nov 2024

Keck Hospital of USC receives ninth "A" Hospital Safety Grade from The Leapfrog Group

Keck Hospital of USC earned an "A" Hospital Safety Grade from The Leapfrog Group, an independent national nonprofit watchdog focused on patient safety.

15 Nov 2024

Duke-NUS team develops test to monitor engineered T cells in cancer treatment

A novel test developed by Duke-NUS researchers enables real-time monitoring of T cells that have been engineered to fight cancer, after re-introduction into the body of a cancer patient.

15 Nov 2024

Artemisinin resistance detected in children with severe malaria in Uganda

Indiana University School of Medicine researchers, in collaboration with colleagues at Makerere University in Uganda, have uncovered evidence of partial resistance to artemisinin derivatives - the primary treatment for malaria - in young children with severe, or "complicated," malaria.

15 Nov 2024

International team releases recommendations for AI use in neuro-oncology

An international, multidisciplinary team of leading neuro-oncology researchers and clinicians has released new recommendations for good clinical practice - a set of guidelines that helps ensure clinical trial results are reliable, and patients are protected - regarding the use of artificial intelligence methods to more accurately diagnose, monitor and treat brain cancer patients.

15 Nov 2024

Computer-assisted CBT and mental health apps effective in reducing anxiety, depression symptoms

Computer-assisted cognitive-behavior therapy (CCBT) and mobile mental health applications warrant continued development and ongoing efforts to increase acceptance among patients and clinicians, according to a review published in the Journal of Psychiatric Practice, part of the Lippincott portfolio from Wolters Kluwer.

15 Nov 2024

Psychedelics may offer anxiety relief through specific brain circuits

New research suggests that it could be possible to separate treatment from hallucinations when developing new drugs based on psychedelics.

15 Nov 2024

UCLA researchers discover netrin1's unexpected role in spinal cord development

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have uncovered an unexpected role for the molecule netrin1 in organizing the developing spinal cord.

15 Nov 2024

Customizable biological sensors activate cancer immunotherapy only in tumor environments

Most cancer treatments – from chemotherapies to engineered immune cells – have a host of side effects, in large part because they affect healthy cells in the body at the same time as targeting tumor cells.

15 Nov 2024

Study finds artemisinin resistance in African children with severe malaria

Mutations in malarial parasites linked to artemisinin-resistance in Southeast Asia have now been found in African children hospitalised for complicated malaria, according to a new study presented at the Annual Meeting of the American Society of Tropical Medicine & Hygiene (ASTMH).

15 Nov 2024

Study focuses on COPD progression in younger populations

Researchers are exploring how small airway abnormalities in younger smokers could help identify who is at risk of developing COPD and establish how the chronic lung disease progresses, according to a new article.

15 Nov 2024

New insights into how IFITM3 protein protects against severe flu

Researchers have identified new roles for a protein long known to protect against severe flu infection – among them, raising the minimum number of viral particles needed to cause sickness.

15 Nov 2024