Animal Model News and Research

RSS

Study: JNK and BNP activity can reverse cardiovascular damage, reduce risk of death from sepsis

Overreaction is rarely useful, and in the case of the human immune system, it can be outright deadly. When the body overreacts to an infection, the result is sepsis - a life-threatening condition that frequently leads to acute organ dysfunction, including deterioration of the heart and blood vessels, which make up the cardiovascular system.

24 Apr 2020

Graphene-based nanomedicine enables targeted cancer treatment at molecular level

"Three" kinds of regalia such as crown, orb, and sward are often necessary to be a high king for conquering the world. For fighting off cancerous diseases, what do we need? This "triple" chemical modified nanomaterial might be save the patient.

23 Apr 2020

Anti-SARS-CoV-2 / COVID-19 antibody: In stock and new formats

In mid-March, we announced the availability of an anti-coronavirus antibody shown to recognize SARS-CoV-2 (also referred to as 2019-nCoV or COVID-19). The anti-SARS clone, CR3022, was first described in 2006, and in early 2020, researchers showed the clone has high affinity for the then-termed 2019-nCoV. Scientists worldwide are now exploring this antibody as a candidate for mono- as well as combination-therapy development.

From Absolute Antibody Ltd 23 Apr 2020

UMB and UMD fund cross-campus research projects

The University of Maryland, Baltimore (UMB) and the University of Maryland, College Park (UMD) are funding new cross-campus research projects as part of a new joint program that seeks to solve big health care challenges through joint research that draws on the institutions world leading expertise in medicine and artificial intelligence.

23 Apr 2020

Accelerating Antibody Discovery with Next-Generation Single-Cell Analysis

Accelerating antibody discovery using picodroplet technology for single cell analysis to condense discovery times down to 1-2 days.

From Fluidic Sciences and Sphere Bio 22 Apr 2020

PiCoVacc vaccine candidate for COVID-19 effective in animal trials

In a new study available on the bioRxiv preprint server, a group of researchers from China report on the pilot-scale production of a purified inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus vaccine candidate (PiCoVacc), shown to induce virus-specific neutralizing antibodies in rats, mice, and non-human primates.

21 Apr 2020

UMA researchers develop ventilator for COVID-19 patients

The ventilator, developed by researchers from the Medical Robotics Research Group of the University of Málaga in a record time of 20 days to strengthen health care response to COVID-19, is already being manufactured, after receiving authorization from the Spanish Agency of Medicines and Medical Devices upon fulfilling all requirements for its approval.

21 Apr 2020

ACE2 receptor expression by SARS-CoV-2 across different animal species

A new report published on the preprint server bioRxiv in April 2020 reports that several species of animals can be infected with relative ease by the SARS-CoV-2 virus that is the causative agent of the currently raging COVID-19 pandemic. This casts much light on the possible natural hosts and routes of transmission of this virus.

20 Apr 2020

Artificial 'candy canes' block viral entry and infection

Viruses are part of the human experience throughout our lives. They cause lots of different illnesses with the current coronavirus pandemic as just one example.

20 Apr 2020

New study raises red flags about strategy to block cancer drug resistance

Sooner or later, most cancer patients develop resistance to the very chemotherapy drugs designed to kill their cancer, forcing oncologists to seek alternatives.

17 Apr 2020

Researchers map function of special group of nerve cells found in the eye

Researchers from Aarhus University have discovered the function of a special group of nerve cells which are found in the eye and which sense visual movement.

16 Apr 2020

New antiviral drug reduces transmission of influenza, study shows

The antiviral drug, baloxavir (tradename Xofluza), is the first treatment for influenza with a new mode of "action" to be licensed in nearly 20 years.

16 Apr 2020

Voluntary exercise could help prevent liver cancer, study shows

Liver cancer is the fourth most common cause of cancer death worldwide and is growing rapidly due to the "diabesity pandemic."

14 Apr 2020

Chemists identify a drug to rescue winter depression-like behavior

A group of animal biologists and chemists at the Institute of Transformative Bio-Molecules, Nagoya University, has used a chemical genomics approach to explore the underlying mechanism of winter depression-like behavior and identified a drug that rescues winter depression-like behavior in medaka fish.

13 Apr 2020

Cats, ferrets more vulnerable to COVID-19 than dogs

A recent Chinese study published on the preprint server BioRxiv finds that cats and ferrets appear to be extremely vulnerable to the virus, but dogs, pigs, and poultry do not seem to contract it. As preprints, papers are not yet peer-reviewed, undergoing only basic scientific screening.

12 Apr 2020

Nanotechnology-based treatment can help alleviate fertility problems linked to endometriosis

Scientists have developed a precise, nanotechnology-based treatment to alleviate the pain and fertility problems associated with endometriosis, a common gynecological condition in women of childbearing age.

7 Apr 2020

Acute-19 becomes first bi-level turbine ventilator for patients affected by COVID-19

The first prototype of a bi-level turbine ventilator for pressure-monitored ventilation in patients affected by COVID-19, Acute-19, developed by Spanish researchers, has just successfully surpassed the validation phase in an animal model at the CEU Cardenal Herrera University of Valencia.

6 Apr 2020