Immune System News and Research

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Northwestern team develops antibody to expose hidden pancreatic cancer cells

Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have uncovered a novel explanation for that resistance: Pancreatic tumors use a sugar-based disguise to hide from the immune system.

3 Nov 2025

New research reveals how human astroviruses enter the body

Human astroviruses are a leading viral cause of the stomach bug-think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries.

3 Nov 2025

Even low PFAS in drinking water raise blood levels, California study shows

Researchers in Southern California found that even low levels of PFAS (“forever chemicals”) in public drinking water lead to measurable increases in blood PFAS concentrations. The study underscores the urgent need for stronger water-quality monitoring and stricter PFAS regulations across non-industrial regions.

2 Nov 2025

Mutated RIG-I receptor causes kidney inflammation through Y-RNA activation

Researchers at the University Hospital Bonn (UKB) and the University of Bonn have discovered how a small, naturally occurring RNA molecule in the kidney activates a mutated immune receptor, triggering a chain reaction.

31 Oct 2025

Scripps Research scientists receive NIH grant to unlock long-term HIV protection

Nearly 40 years after HIV was first identified, the virus continues its devastating march across the globe. Today, 38 million people live with HIV, and each year brings 1.5 million new infections and 650,000 more deaths-while nearly 10 million people still lack access to life-saving medicines.

31 Oct 2025

How nerve cells in the gut adapt to microbial and immune challenges

Ramnik Xavier, MD, PhD, of the Department of Molecular Biology at Massachusetts General Hospital, is the senior author of a paper published in Science, "Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation."

31 Oct 2025

Evidence of previously unrecognized hub in the brain's lymphatic drainage system revealed

How does the brain take out its trash? That is the job of the brain's lymphatic drainage system, and efforts to understand how it works have pushed the boundaries of brain-imaging technologies.

31 Oct 2025

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Cancer immunotherapy, which uses drugs that stimulate the body's immune cells to attack tumors, is a promising approach to treating many types of cancer. However, it doesn't work well for some tumors, including ovarian cancer.

31 Oct 2025

Pharmacists can help control blood sugar in cancer patients with diabetes

People with cancer who received diabetes care from clinical pharmacists achieved significantly better blood sugar control, according to new research from the University of California San Diego.

30 Oct 2025

Fundamental challenges and cutting-edge strategies in developing new GBM CAR-T therapies

Glioblastoma (GBM), the most aggressive primary brain tumor, continues to portend a poor prognosis with median survival under two years, despite standard care involving surgery, radiation, and temozolomide chemotherapy.

30 Oct 2025

Research identifies biomarkers in blood to fine-tune breast cancer interventions

Doctors may be able to spare patients unnecessarily aggressive breast cancer treatments by collecting and testing cancer cells in patients' blood, research from the University of Michigan and the University of Kansas suggests.

30 Oct 2025

Scripps Research professor wins $3.2 million grant to unravel the mysteries of type 1 diabetes

Luc Teyton, professor in the Department of Immunology and Microbiology at Scripps Research, has received a five-year, $3.2 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to help answer how type 1 diabetes manifests and develop potential therapeutics to reverse or prevent the disease.

29 Oct 2025

Rapamycin shows promise in treating cold tumors with specific gene mutation

Immune checkpoint inhibitors (ICIs) emerged in the US about 15 years ago as an exciting class of cancer treatments that have achieved complete and durable remissions for thousands of people with end-stage metastatic cancers.

29 Oct 2025

Understanding age-related changes in T cells and vaccine response

As flu season approaches and public health officials roll out their annual push for vaccination, Allen Institute scientists are learning why vaccines can trigger a weaker response in older adults, around age 65, and what can be done to improve them.

29 Oct 2025

Experimental compound reduces cell death, inflammation, and organ damage in diabetes

An experimental compound reduced the cell death, inflammation, and organ damage seen with diabetes.

29 Oct 2025

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Peripheral afferent neurons - nerves that send signals from all areas of the body to the central nervous system (brain and spinal cord) - are known to infiltrate and grow within malignant bone tumors called osteosarcomas, often accompanied by severe pain.

29 Oct 2025

Some acute and chronic viral infections linked to increased risk of cardiovascular disease

In the weeks following a bout of influenza or COVID, the risk of heart attack or stroke may rise dramatically, and chronic infections such as HIV may increase the long-term risk of serious cardiovascular disease events, according to new, independent research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

29 Oct 2025

Exploring the gut-brain-immune axis in neurodegeneration

Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS), represent a growing global health burden, particularly in aging populations.

28 Oct 2025

Hypoxia weakens the body's infection defense by changing genetic material of neutrophils

Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body's ability to fight infection, new research shows.

28 Oct 2025

$Reducing femoral fractures in total hip replacement with safer implant designs$

Reducing femoral fractures in total hip replacement with safer implant designs

As populations continue to age, total hip replacement (THR) is becoming an increasingly common surgical procedure.

28 Oct 2025

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Immune System News and Research

Northwestern team develops antibody to expose hidden pancreatic cancer cells

New research reveals how human astroviruses enter the body

Even low PFAS in drinking water raise blood levels, California study shows

Mutated RIG-I receptor causes kidney inflammation through Y-RNA activation

Scripps Research scientists receive NIH grant to unlock long-term HIV protection

How nerve cells in the gut adapt to microbial and immune challenges

Evidence of previously unrecognized hub in the brain's lymphatic drainage system revealed

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Pharmacists can help control blood sugar in cancer patients with diabetes

Fundamental challenges and cutting-edge strategies in developing new GBM CAR-T therapies

Research identifies biomarkers in blood to fine-tune breast cancer interventions

Scripps Research professor wins $3.2 million grant to unravel the mysteries of type 1 diabetes

Rapamycin shows promise in treating cold tumors with specific gene mutation

Understanding age-related changes in T cells and vaccine response

Experimental compound reduces cell death, inflammation, and organ damage in diabetes

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Some acute and chronic viral infections linked to increased risk of cardiovascular disease

Exploring the gut-brain-immune axis in neurodegeneration

Hypoxia weakens the body's infection defense by changing genetic material of neutrophils

Reducing femoral fractures in total hip replacement with safer implant designs

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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