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Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination amongst healthcare workers

The heterologous ChAd/BNT combination confers better protection against SARS-CoV-2 infection than the homologous BNT/BNT combination in a real-world observational study of healthcare workers.

27 Oct 2021

bit.bio expands Board of Directors with appointment of entrepreneurs and Nobel Laureate

Today bit.bio welcomed three new members to its Board of Directors, who bring their respective experience of turning world-class science into new industries.

From bit.bio 27 Oct 2021

Enzymes with diverse functions can be rationally harnessed to offer traceless protein synthesis

A multi-enzyme platform is developed for sequence-unconstrained traceless protein synthesis and modification with either synthetic peptides or recombinant proteins, according to a new study out of Chinese Academy of Sciences and Fresenius Kabi.

22 Oct 2021

Researchers discover how Staphylococcus aureus protects itself against important antibiotic

The skin bacterium Staphylococcus aureus often develops antibiotic resistance. It can then cause infections that are difficult to treat.

21 Oct 2021

Cat bacteria likely to form the basis for novel therapeutics against severe skin infections

Researchers at University of California San Diego School of Medicine used bacteria found on healthy cats to successfully treat a skin infection on mice. These bacteria may serve as the basis for new therapeutics against severe skin infections in humans, dogs and cats.

20 Oct 2021

Many people's T-cells recognize the same components of SARS-CoV-2

A new study published on the bioRxiv* preprint aimed to identify highly immunoprevalent CD8 T-cell epitopes specific to SARS-CoV-2 that are confirmed to be endogenously processed and presented on frequently expressed HLA alleles.

18 Oct 2021

UC Davis researchers publish the first atlas of metabolites in the mouse brain

The first atlas of metabolites in the mouse brain has been published by a team led by UC Davis researchers.

18 Oct 2021

Research indicates that mRNA vaccine-induced T cells respond robustly to new SARS-CoV-2 variants

To address the gaps in the knowledge, a team of researchers from the University of California and the Gladstone Institute of Virology conducted 39-parameter phenotyping by cytometry by time of flight (CyTOF) on 33 longitudinal specimens from 11 mRNA-vaccinated individuals, of which six had previously been infected and recovered from COVID-19.

18 Oct 2021

Fibrin immunotherapy may resolve blood clotting induced by SARS-CoV-2

A group of researchers from the United States discovered that the spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can induce the formation of highly inflammatory blood clots amenable to neutralization by a fibrin-targeting monoclonal antibody – opening the door for a completely new strategy to reduce thrombotic inflammation in coronavirus disease 2019 (COVID-19).

17 Oct 2021

Sleep-enhancing peptides in cow’s milk could help develop new, natural sleep remedies

According to time-honored advice, drinking a glass of warm milk at bedtime will encourage a good night's rest.

13 Oct 2021

COVID-19 vaccination induces transient increase in cellular and antibody responses to S1 antigenic sequence

Scientists have characterized T-cell, B-cell, and IgG responses to S antigenic sequences to evaluate vaccine effectiveness.

13 Oct 2021

Rapid measurement of SARS-CoV-2 spike T-cells

Researchers measure SARS-CoV-2 T-cell responses in individuals vaccinated or in those who developed immunity from a prior natural infection.

12 Oct 2021

COVID-19 vaccination elicits broader antibody response to SARS-CoV-2 spike than infection

A recent study demonstrates that antibodies generated in response to mRNA-based COVID-19 vaccination target more epitopes across the spike protein.

11 Oct 2021

Antibody validation and rapid peptide mapping technology

In this interview, News-Medical speaks to Bin Ma, President of Rapid Novor, about antibody validation and rapid peptide mapping technology.

From Rapid Novor Inc 11 Oct 2021

TTUHSC investigator evaluates the potential of neurolysin as a therapeutic target for stroke

Ischemic stroke, the second leading cause of death worldwide, occurs when a vessel to the brain is blocked, reducing blood flow to the brain and depriving it of critical supplies of oxygen and nutrients.

8 Oct 2021

Novel peptide-drug conjugate enhances the efficacy of immunotherapy in preclinical cancer models

A peptide-drug conjugate that targets the acidic environment of cancer cells enhanced the efficacy of immune checkpoint inhibitors in preclinical cancer models, according to results presented at the AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics, held October 7-10, 2021.

7 Oct 2021

Autoimmune disease drug helps prevent lung damage, death in mice with SARS-CoV-2 infection

In a new paper, researchers at the University of Illinois Chicago report that a drug approved for treating patients with autoimmune disease helped to prevent lung damage and death in mice infected with the SARS-CoV-2 virus, which causes COVID-19 in humans.

6 Oct 2021

Scientists analyze if T-cell tests can be used to determine whether people had COVID-19

Can T-cell tests be used to determine whether people have had COVID-19? Scientists at Uppsala University and Karolinska Institutet have jointly analysed this issue under the aegis of the COMMUNITY study at Danderyd Hospital. Their study is published in the scientific journal PLOS ONE.

4 Oct 2021

New system synthetically reconnects neural circuits using neuropeptides from Hydra

For two people to communicate in a loud, crowded room, they need to be standing side by side. The same is often true for neurons in the brain. But the same way a cell phone allows two people to communicate clearly across the room, new research at the Marine Biological Laboratory (MBL) opened up a new channel of communication in the worm C. elegans brain.

30 Sep 2021

New analysis reveals distinct differences between molecular profiles of 3D and 2D cultured cells

Oncotarget published "Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells" which reported that to ascertain phenotypical differences between these two distinct culture conditions, these authors carried out a comparative proteomic analysis of a membrane fraction obtained from 3D- and 2D-cultured NSCLC model cell line NCI-H23.

29 Sep 2021

Peptides News and Research

Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination amongst healthcare workers

bit.bio expands Board of Directors with appointment of entrepreneurs and Nobel Laureate

Enzymes with diverse functions can be rationally harnessed to offer traceless protein synthesis

Researchers discover how Staphylococcus aureus protects itself against important antibiotic

Cat bacteria likely to form the basis for novel therapeutics against severe skin infections

Many people's T-cells recognize the same components of SARS-CoV-2

UC Davis researchers publish the first atlas of metabolites in the mouse brain

Research indicates that mRNA vaccine-induced T cells respond robustly to new SARS-CoV-2 variants

Fibrin immunotherapy may resolve blood clotting induced by SARS-CoV-2

Sleep-enhancing peptides in cow’s milk could help develop new, natural sleep remedies

COVID-19 vaccination induces transient increase in cellular and antibody responses to S1 antigenic sequence

Rapid measurement of SARS-CoV-2 spike T-cells

COVID-19 vaccination elicits broader antibody response to SARS-CoV-2 spike than infection

Antibody validation and rapid peptide mapping technology

TTUHSC investigator evaluates the potential of neurolysin as a therapeutic target for stroke

Novel peptide-drug conjugate enhances the efficacy of immunotherapy in preclinical cancer models

Autoimmune disease drug helps prevent lung damage, death in mice with SARS-CoV-2 infection

Scientists analyze if T-cell tests can be used to determine whether people had COVID-19

New system synthetically reconnects neural circuits using neuropeptides from Hydra

New analysis reveals distinct differences between molecular profiles of 3D and 2D cultured cells

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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