Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

The model for end-stage liver disease

A review of the studies on the Model for End-Stage Liver Disease (MELD) found that it is an accurate predictor of survival of patients with a variety of liver diseases, is particularly useful in allocating organs for liver transplants, and can also be used to help determine the course of treatment in certain cases. However, it is possible to improve the accuracy of the model and efforts at refining will continue.

5 Mar 2007

New drug delivery method incorporates drug molecules in fat

Devastating blood-borne fungal infections that can be lethal for HIV/AIDS, cancer, and organ transplant patients may be treated more successfully, thanks to a new drug delivery method developed by researchers at the University of British Columbia in Vancouver.

5 Mar 2007

FDA investigating norovirus linked to San Antonio Bay oysters

The U.S. Food and Drug Administration (FDA) is investigating an outbreak of norovirus-associated illness linked to eating raw oysters harvested from San Antonio Bay, TX.

4 Mar 2007

Surgery, shock waves both effective for removing kidney stones

Two common methods for removing kidney stones - surgery and shock wave treatments - are effective and safe, and neither is clearly superior to the other, researchers report in a new systematic review of studies. But these conclusions aren't based on particularly strong data, the researchers say.

1 Mar 2007

Sunitinib halts progress of metastatic kidney cancer

Research has shown the efficacy of a pharmaceutical drug known as sunitinib which halts progress of metastatic kidney cancer.

1 Mar 2007

Common painkillers raise mens' risk of hypertension

Researchers in the United States believe that regular use of common painkillers such as Acetaminophen (paracetomol), ibuprofen and aspirin, increases the risk of high blood pressure and consequently heart disease in men.

28 Feb 2007

Women in the UK to trade eggs for IVF treatment

According to the fertility regulator in the UK women there will soon be able to donate their eggs for medical research.

21 Feb 2007

Regulator of cholesterol production identified

By first probing the way primitive yeast make cholesterol, a team of scientists has discovered a long-sought protein whose human counterpart controls cholesterol production and potentially drug metabolism.

20 Feb 2007

Procalcitonin helps predict prognosis among those with peritonitis

Monitoring blood levels of a compound known as procalcitonin in patients with peritonitis (a serious intra-abdominal infection) could help identify patients at increased risk of organ failure and death, according to a report in the February issue of Archives of Surgery.

20 Feb 2007

Maraviroc to receive accelerated review in U.S. and Europe

Pfizer announced today that marketing authorization applications for maraviroc will receive accelerated review in both the United States and Europe. Accelerated reviews are granted to potential medicines that, if approved, would represent significant improvements over current therapies.

13 Feb 2007

Women who donate eggs for stem cell research face few health risks

Women who donate their eggs for stem cell research or in vitro fertilization are not at increased risk of health complications, and most of the risks are a result of the hormones used to stimulate their bodies to release more than one egg, according to a report commissioned by the California Institute of Regenerative Medicine and released by the Institute of Medicine, Bloomberg reports.

13 Feb 2007

Researchers discover how to fight iron disorders with a drug against hypertension

We all know that iron deficiencies are dangerous, but also too much iron is bad for our health. Our body stores excess iron in various tissues, where it can lead to organ failure and even death if not treated before irreversible damage has occurred.

12 Feb 2007

GenoMed discovers African gene

GenoMed has announced that it has found the "African gene," responsible for the much higher incidence of diabetes, high blood pressure, and kidney failure among people of African ancestry than whites.

12 Feb 2007

Cancer breakthrough - first treatment to directly target tumor supply

For the first time, physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City have demonstrated in patients the ability of an antibody to directly target the blood supply of a wide variety of tumors, leaving healthy tissues unharmed.

12 Feb 2007

New microscopy technology

Research is finding evidence that may solve one of the great puzzles of 21st Century medicine using a new microscopy technology known as CytoViva.

11 Feb 2007

Aprotinin use associated with an increased risk of death following CABG surgery

Aprotinin, a drug used for limiting blood loss in patients undergoing cardiac surgery, is associated with an increased risk of death during five years following the surgery, according to a new study in the February 7 issue of JAMA: The Journal of the American Medical Association.

7 Feb 2007

Gastric surgery the latest idea in the U.S. to resolve obesity in children

The popularity of stomach surgery in the United States to resolve obesity has greatly increased in the last few years but operating on obese children has rarely been done because of the considerable risks involved.

5 Feb 2007

New drug to treat kidney failure during septic shock

Research from Melbourne's Howard Florey Institute and the Austin Hospital has resulted in a drug to treat kidney failure during septic shock, which will be trialled at the Austin Hospital from mid-2007.

29 Jan 2007

Link between MRI contrast agent and nephrogenic systemic fibrosis

New research has shown a possible association between a popular magnetic resonance imaging (MRI) contrast agent and the incidence of a rare disease called nephrogenic systemic fibrosis (NSF) in patients with kidney disease, according to an editorial appearing in the March issue of Radiology.

28 Jan 2007

Possible reason for severe side-effects of Northwick Park clinical trial

A possible reason why the Northwick Park clinical trial of the drug TGN1412 caused multiple organ failure in human volunteers is revealed in research presented at a conference near Paris.

25 Jan 2007