Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Scientists uncover cerebrospinal fluid markers for Alzheimer's detection and treatment

Researchers map the unique genetic regulation of proteins in human cerebrospinal fluid, identifying potential targets for Alzheimer’s treatments.

12 Nov 2024

TYK2 inhibition may offer new strategy to reduce tau toxicity in Alzheimer's

Researchers at Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital and collaborating institutions discovered that the enzyme TYK2 transforms the normal protein tau into one that accumulates in the brain and contributes to the development of Alzheimer's disease in animal models.

12 Nov 2024

Study links asthma to memory deficits in children

Asthma is associated with memory difficulties in children, and early onset of asthma may exacerbate memory deficits, according to a new study from the University of California, Davis.

11 Nov 2024

Study reveals high prevalence of unrecognized cognitive impairment in vulnerable older adults

One of the first studies to investigate the prevalence of unrecognized cognitive impairment among patients seen at Federally Qualified Health Centers, has found that it is ubiquitous, especially among minoritized older adults.

8 Nov 2024

AI-READI consortium launches groundbreaking diabetes data study

Researchers today (Nov. 8, 2024) are releasing the flagship dataset from an ambitious study of biomarkers and environmental factors that might influence the development of type 2 diabetes.

8 Nov 2024

New study links genetic mosaicism to lower Alzheimer’s risk in adults with Down syndrome

Study finds mosaicism in Down syndrome reduces Alzheimer's risk, providing new insights into genetic influences on cognitive decline and dementia progression.

8 Nov 2024

Traditional Chinese herb shows promise against Alzheimer’s and Parkinson’s

Zizyphi spinosi semen demonstrates neuroprotective effects, improving cognitive function and reducing amyloid and tau pathology in models of aging and dementia.

8 Nov 2024

C-Path announces important leadership appointments in neurology and Alzheimer's research

Critical Path Institute (C-Path) today announced key leadership appointments: Diane Stephenson, Ph.D., has been promoted to Vice President of Neurology, and Nadine Tatton, Ph.D., has been welcomed as the new Executive Director of C-Path's Critical Path for Alzheimer's Disease (CPAD) Consortium.

7 Nov 2024

Anti-inflammatory cytokine linked to capillary obstruction and cognitive decline in diabetes

Elevated IL-10 in diabetes causes capillary obstruction, linked to cognitive deficits. Blocking IL-10 receptors shows promise for improving brain function.

7 Nov 2024

Polyphenol-rich Mediterranean diets could help keep the brain younger

A study reveals that Mediterranean and green-MED diets rich in polyphenols may slow brain aging and reduce neurodegeneration through improved glycemic control.

6 Nov 2024

Ancient herb shows promise in fighting dementia

Attempts to discover a breakthrough dementia drug might be drawing attention these days, but traditional medicinal products can offer hints for preventive medicine.

6 Nov 2024

AI model predicts Alzheimer’s progression with new insights into racial and sex-based disparities

Researchers developed a deep learning model that predicts Alzheimer’s progression with high accuracy, highlighting differences in disease progression across race and sex.

5 Nov 2024

Revised diagnostic criteria seek to avoid over-diagnosis of Alzheimer’s disease

Diagnosis of Alzheimer's Disease (AD) is currently largely based on the presence of biomarkers. This may lead to a problematic over-diagnosis if this is incorrectly interpreted.

5 Nov 2024

New Alzheimer's guidelines focus on risk, not diagnosis, in healthy adults

Researchers from the International Working Group recommend categorizing biomarker-positive, cognitively normal individuals as "at risk" for Alzheimer's to avoid unnecessary diagnoses and emphasize preventive care.

4 Nov 2024

UT Dallas researchers awarded $3.7 million NIH grant for brain aging study

Two researchers from The University of Texas at Dallas' Center for Vital Longevity (CVL) have received a five-year grant from the National Institutes of Health (NIH) to expand their study of brain structure, function and cognition across time through the use of powerful high-resolution imaging.

4 Nov 2024

New model sheds light on APOE4's role in Alzheimer's pathology

In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein - the most important genetic risk factor for Alzheimer's disease - the same cells cause harmful inflammation and clumps of misfolded proteins, according to a new study by scientists at Gladstone Institutes.

4 Nov 2024

Grant awarded to build a portable PET scanner for early Alzheimer's detection

Weill Cornell Medicine researchers have received a five-year $6.2 million grant from the National Institute on Aging, part of the National Institutes of Health, to build a portable, high-resolution Positron Emission Tomography (PET) scanner that can detect the earliest stages of Alzheimer's disease.

4 Nov 2024

SpaceX CRS-31 supports heart health, neurodegeneration, and student science

More than 25 payloads sponsored by the International Space Station (ISSInternational Space Station) National Laboratory, including technology demonstrations, in-space manufacturing, student experiments, and multiple projects funded by the U.S. National Science Foundation (NSF), are bound for the orbiting outpost.

4 Nov 2024

Researchers achieve accurate EV analysis to detect brain disease

Brain disorders like Parkinson's (PD) or Alzheimer's Disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or even stop their disease, but there is currently no way to diagnose brain disorders at those pre-symptomatic stages.

3 Nov 2024

International experts propose revised Alzheimer's disease definitions

Today, Prof. Howard Feldman presented revised diagnostic criteria for Alzheimer's disease at the Clinical Trials on Alzheimer's Disease (CTAD) Conference in Madrid on behalf of the International Working Group (IWG).

1 Nov 2024

Alzheimer's Disease News and Research

Further Reading

Scientists uncover cerebrospinal fluid markers for Alzheimer's detection and treatment

TYK2 inhibition may offer new strategy to reduce tau toxicity in Alzheimer's

Study links asthma to memory deficits in children

Study reveals high prevalence of unrecognized cognitive impairment in vulnerable older adults

AI-READI consortium launches groundbreaking diabetes data study

New study links genetic mosaicism to lower Alzheimer’s risk in adults with Down syndrome

Traditional Chinese herb shows promise against Alzheimer’s and Parkinson’s

C-Path announces important leadership appointments in neurology and Alzheimer's research

Anti-inflammatory cytokine linked to capillary obstruction and cognitive decline in diabetes

Polyphenol-rich Mediterranean diets could help keep the brain younger

Ancient herb shows promise in fighting dementia

AI model predicts Alzheimer’s progression with new insights into racial and sex-based disparities

Revised diagnostic criteria seek to avoid over-diagnosis of Alzheimer’s disease

New Alzheimer's guidelines focus on risk, not diagnosis, in healthy adults

UT Dallas researchers awarded $3.7 million NIH grant for brain aging study

New model sheds light on APOE4's role in Alzheimer's pathology

Grant awarded to build a portable PET scanner for early Alzheimer's detection

SpaceX CRS-31 supports heart health, neurodegeneration, and student science

Researchers achieve accurate EV analysis to detect brain disease

International experts propose revised Alzheimer's disease definitions

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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